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Nanomaterials for Clinical Applications

Nanomaterials for Clinical Applications
Case Studies in Nanomedicines

by Costas Demetzos,Natassa Pippa

  • Publisher : Elsevier
  • Release : 2020-02-14
  • Pages : 322
  • ISBN : 0128168765
  • Language : En, Es, Fr & De
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Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice

Nanomaterials for Medical Applications

Nanomaterials for Medical Applications
A Book

by Zoraida Aguilar

  • Publisher : Newnes
  • Release : 2012
  • Pages : 461
  • ISBN : 0123850894
  • Language : En, Es, Fr & De
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This title covers recent advances in a variety of biomedical applications of nanostructured materials, as the field evolves from prototype device to real-world application. It presents the main types of nanomaterial used in medical application today: semiconductor nanomaterials, Magnetic nanomaterials, metal nanoparticles, Carbon nanomaterials, Hydrogel nanocomposites, Liposomes, Dendrimers, Polymer nanocomposites, and Biodegradable polymers. Structurally the work is demarcated into the six most popular areas of research: (1) biocompatibility of nanomaterials with living organisms in their various manifestations (2) nanobiosensors for clinical diagnostics, detecting biomolecules which are useful in the clinical diagnosis of genetic, metabolically acquired, induced or infectious disease (3) targeted drug delivery for nanomaterials in their various modifications (4) nanomedical devices and structures which are used in the development of implantable medical devices and structures such as nanorobots (5) nanopharmacology, as novel nanoparticles are increasingly engineered to diagnose conditions and recognize pathogens, identify ideal pharmaceutical agents to treat the condition or pathogens,fuel high-yield production of matched pharmaceuticals (potentially in vivo), locate, attach or enter target tissue, structures or pathogens; and dispense the ideal mass of matched biological compound to the target regions (6) nanotoxicology and remediation, which focuses on finished and on-going various toxicity evaluations on various nanomaterials that are used and currently being developed for medical applications Discusses the most important biomedical applications and devices of nanomaterials: drug delivery, medical imaging, gene therapy, nanorobots, biosensors and diagnostics Focuses on current commercialized techniques and applications, ensuring the work is entirely relevant to a rapidly evolving field Reviews the most recent studies on nanomaterial toxicity, thereby responding to the widescale private, policy and public interest in nanoscience

Nanomaterials and Neoplasms

Nanomaterials and Neoplasms
Towards Clinical Applications

by Valerio Voliani

  • Publisher : Unknown Publisher
  • Release : 2019-03-31
  • Pages : 600
  • ISBN : 9789814800396
  • Language : En, Es, Fr & De
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Nanomaterials have attracted increasing interest due to their potential to revolutionize the diagnosis and treatment of many diseases, especially neoplasms. Interestingly, there is a huge imbalance between the number of proposed nanoplatforms and the few ones approved for clinical applications. This disequilibrium affects, in particular, noble metal nanoparticles, which present no approved platforms and few candidates in clinical trials because of the issue of persistence. This book comprises hot papers on (i) the main behaviors of nanomaterials, (ii) key features needed for clinical translation, and (iii) market analysis of nanomaterials on the bedside. The main aim of this book is to offer a more industrial/clinical point of view to students and researchers, together with the knowledge of regulatory agencies. It is a great reference for advanced undergraduate- and graduate-level students of nanotechnology and researchers in materials science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in cancer theranostics.

Clinical Applications of Magnetic Nanoparticles

Clinical Applications of Magnetic Nanoparticles
A Book

by Nguyen TK Thanh

  • Publisher : CRC Press
  • Release : 2018-02-06
  • Pages : 490
  • ISBN : 1351685422
  • Language : En, Es, Fr & De
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Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.

Magnetic Nanoparticles

Magnetic Nanoparticles
From Fabrication to Clinical Applications

by Nguyen TK Thanh

  • Publisher : CRC Press
  • Release : 2012-02-01
  • Pages : 616
  • ISBN : 9781439869321
  • Language : En, Es, Fr & De
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Offering the latest information in magnetic nanoparticle (MNP) research, Magnetic Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. This book, written by some of the most qualified experts in the field, not only fills a hole in the literature, but also bridges the gaps between all the different areas in this field. Translational research on tailored magnetic nanoparticles for biomedical applications spans a variety of disciplines, and putting together the most significant advances into a practical format is a challenging task. Balancing clinical applications with the underlying theory and foundational science behind these new discoveries, Magnetic Nanoparticles: From Fabrication to Clinical Applications supplies a toolbox of solutions and ideas for scientists in the field and for young researchers interested in magnetic nanoparticles.

Nanotechnology in Endodontics

Nanotechnology in Endodontics
Current and Potential Clinical Applications

by Anil Kishen

  • Publisher : Springer
  • Release : 2015-03-18
  • Pages : 199
  • ISBN : 3319135759
  • Language : En, Es, Fr & De
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This book provides detailed information on the emerging applications of nanomaterials and nanoparticles within endodontics, highlighting the exciting potential clinical impact of nanotechnology in the field. The range of applications covered is diverse, encompassing drug and gene delivery, tissue engineering, antibacterial strategies, dentin tissue stabilization, dentin pulp regeneration and use in restorative and endodontic materials. Important scientific background information relating to each application is provided, with clear coverage of basic principles. In addition, potential pitfalls are identified and explained. The cytotoxicity of nanomaterials and nanoparticles is also addressed in a separate chapter. The book will be of value both for endodontic practitioners and for all scientists and graduate students who are interested in the application of nanotechnology in endodontics.

Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy

Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy
A Book

by C. Alexiou

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2011-10-06
  • Pages : 210
  • ISBN : 380559819X
  • Language : En, Es, Fr & De
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Nanomedicine - the application of nanotechnology to human health - is a promising field of research at the interface of physical, chemical, biological, and medical science. Recent advances have made it possible to analyze biological systems at cellular and subcellular levels, offering numerous promising approaches to improve medical diagnosis and therapy. It is expected that nanomedicine will have a great impact especially on drug delivery and imaging. In this context, the development of targeted, highly specific nanoparticles is of pivotal importance. The results of these advances will offer personalized diagnostic tools and treatments in the future. Based on the 2nd Else Kröner-Fresenius-Symposium, this book presents a broad spectrum of topics ranging from nanoscale drug delivery/drug design to nanotoxicity and from diagnostics and imaging to therapeutic applications including antibody therapies. The contributions are authored by leading experts in the field and provide an excellent overview of the current knowledge in nanomedicine. Due to the interdisciplinary nature of the subject area this volume will be of special interest to physicians, biologists, chemists, engineers, and physicists as well as to students in the respective fields.

Nanotechnology for Biomedical Imaging and Diagnostics

Nanotechnology for Biomedical Imaging and Diagnostics
From Nanoparticle Design to Clinical Applications

by Mikhail Y. Berezin

  • Publisher : John Wiley & Sons
  • Release : 2015-02-02
  • Pages : 520
  • ISBN : 1118873149
  • Language : En, Es, Fr & De
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Nanotechnology for Biomedical Imaging and Diagnostics: FromNanoparticle Design to Clinical Applications reflects upon theincreasing role of nanomaterials in biological and medical imaging,presenting a thorough description of current research as wellas future directions. With contributions from experts innanotechnology and imaging from academia, industry, andhealthcare, this book provides a comprehensive coverage of thefield, ranging from the architectural design of nanomaterials totheir broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology andbioimaging Provides comprehensive coverage of the field, ranging from thearchitectural design of nanomaterials to their broad imagingapplications in medicine Written by well-recognized experts in academia, industry, andhealthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research anddiagnostic topics, this book will appeal to students, scientiests,and healthcare professionals alike

Emerging Nanotechnologies in Dentistry

Emerging Nanotechnologies in Dentistry
Materials, Processes, and Applications

by Karthikeyan Subramani,Waqar Ahmed

  • Publisher : William Andrew
  • Release : 2012
  • Pages : 410
  • ISBN : 1455778621
  • Language : En, Es, Fr & De
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Nanotechnology and the future of Dentistry -- Nanoparticles for Dental Materials: Synthesis, analysis and Applications -- Antimicrobial nanoparticles in Restorative Composites -- Nanotechnology in operative dentistry: a perspective approach of history, mechanical behavior and clinical application -- Nanotechnology and dental implants -- Titanium surface modification techniques for dental implants - From microscale to nanoscale -- Titanium nanotubes as carriers of osteogenic growth factors and antibacterial drugs for applications in dental implantology -- Cellular responses to nanoscale surface modifications of titanium implants for dentistry and bone tissue engineering applications -- Corrosion Resistance of Ti6Al4V with Nanostructured TiO2 Coatings -- Multiwalled Carbon Nanotubes/Hydroxyapatite Nanoparticles incorporated GTR membranes -- Fabrication of PEG hydrogel micropatterns by Soft-photolithography and PEG hydrogel as Guided Bone Regeneration membrane in dental implantology -- Na ...

Biomedical Nanomaterials

Biomedical Nanomaterials
A Book

by Yuliang Zhao

  • Publisher : John Wiley & Sons
  • Release : 2016-12-12
  • Pages : 504
  • ISBN : 3527337989
  • Language : En, Es, Fr & De
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The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.

Scientific and Clinical Applications of Magnetic Carriers

Scientific and Clinical Applications of Magnetic Carriers
A Book

by Urs H feli,Wolfgang Schütt,Joachim Teller,Maciej Zborowski

  • Publisher : Springer Science & Business Media
  • Release : 1997-07-31
  • Pages : 628
  • ISBN : 9780306456879
  • Language : En, Es, Fr & De
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Proceedings of an international conference held in Rostock, Germany, September 5-7, 1996

Nanobiomaterials in Clinical Dentistry

Nanobiomaterials in Clinical Dentistry
A Book

by Karthikeyan Subramani,Waqar Ahmed

  • Publisher : Elsevier
  • Release : 2019-04-14
  • Pages : 692
  • ISBN : 0128158875
  • Language : En, Es, Fr & De
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Nanobiomaterials in Clinical Dentistry, Second Edition shows how a variety of nanomaterials are being used to solve problems in clinical dentistry. New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants). The book's chapters discuss the advantages and challenges of using nanomaterials and include case studies to illustrate how a variety of materials are best used in research and practice. Contains information from an interdisciplinary, international group of scientists and practitioners in the fields of nanomaterials, dental implants, medical devices and clinical practice Presents a comprehensive reference on the subject that covers material fabrication and the use of materials for all major diagnostic and therapeutic dental applications--repair, restoration, regeneration, implants and prevention Complements the editors' previous book on nanotechnology applications for dentistry

Nanomaterials in Advanced Medicine

Nanomaterials in Advanced Medicine
A Book

by Hossein Hosseinkhani

  • Publisher : John Wiley & Sons
  • Release : 2019-08-05
  • Pages : 224
  • ISBN : 3527345493
  • Language : En, Es, Fr & De
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A comprehensive and multidisciplinary review of the fundamental concepts and medical applications of nanomaterials development technology Nanomedicine offers a range of multi-interdisciplinary approaches and brings together the field of chemistry, pharmaceutical science, biology, and clinical medicines by focusing on design and preparation of biodegradable or non-biodegradable biomaterials for their biological, medical, and pharmaceutical applications. Nanomaterials in Advanced Medicine reviews the concepts and applications of the combination of the technology of biology and engineering that are emerging as an integral aspect of today?s advanced medicine. Nanomedicine provides the technology for imaging, cancer treatment, medical tools, bone treatment, drug delivery, diagnostic tests, drug development, angiogenesis and aims to exploit the improved and often novel physical, chemical, and biological properties of materials at the nanometer scale. Designed to provide a broad survey of the field, Nanomaterials in Advanced Medicine is divided into three main sections: Nanophysics, Nanochemistry, and Nanomedicine. Each chapter describes in detail the most current and valuable methods available and contains numerous references to the primary literature. This important book: -Offers a field guide for biologists and physicians who want to explore the fascinating world of nanotechnology -Contains a comprehensive review of the topic from a noted expert in the field -Includes an introduction to nanotechnology and explores the synthesis, structure and properties of various types of nanobiomaterials -Bridges the gap between various aspects of nanomaterials? development technology and their applications Written for pharmaceutical chemists, biotechnologists, life scientists, materials scientists, polymer chemists, and biochemists, Nanomaterials in Advanced Medicine provides a must-have guide to the fundamental concepts and current applications of nanomaterials in the medical field.

Behaviors and Persistence of Nanomaterials in Biomedical Applications

Behaviors and Persistence of Nanomaterials in Biomedical Applications
A Book

by Domenico Cassano,Valerio Voliani

  • Publisher : John Wiley & Sons
  • Release : 2018-07-18
  • Pages : 258
  • ISBN : 1119418275
  • Language : En, Es, Fr & De
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In the last two decades, several promising engineered nanomaterials that combine therapeutic features and imaging functionalities have been presented, but very few have arrived on the market. The purpose of this book is to collect and comprehensively discuss the advances in this current and exciting topic in order to promote and enhance its growth. In the first part, a general introduction about the main features of both organic and inorganic nanomaterials is provided. Then, the most promising and innovative applications for cancer treatment and diagnostic are introduced. In the second part, an analysis of the nanomaterials in the market for healthcare applications is presented. The issue of unwanted accumulation of metals in organisms after the designed action is then discussed. Finally, the most recent progresses in the design of nanomaterials that are able to escape from organisms after the selected action are comprehensively described, and the perspectives of this exciting field provided.

Nano Medicine and Nano Safety

Nano Medicine and Nano Safety
Recent Trends and Clinical Evidences

by Malay K. Das

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 9811562555
  • Language : En, Es, Fr & De
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Dental Applications of Nanotechnology

Dental Applications of Nanotechnology
A Book

by Ramesh S. Chaughule

  • Publisher : Springer
  • Release : 2018-08-29
  • Pages : 277
  • ISBN : 3319976346
  • Language : En, Es, Fr & De
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This book discusses current trends and potential areas of nanotechnology applications in dental materials. Dentistry is undergoing yet another change to benefit mankind via the discipline of nanodentistry. A variety of nanostructures such as nanorobots, nanospheres, nanofibers, nanorods, etc., have been studied for various applications in dentistry and medicine. Preventive dentistry has also utilized nanodentistry to develop the nanomaterials for inclusion in a variety of oral health-care products. Methods to prevent and combat dental problems have been devised, discussed, and implemented since ancient times; however, there is a constant need for improved tools and techniques. This book is relevant academically for undergraduate and post-graduate dental students, dental practitioners, researchers, and faculties of dental universities, as this book explores the application of various nanobiomaterials in dentistry, discusses current research in dental nanomaterials and potential future areas of interest, and examines the use of nanotechnology in various fields of dentistry.

Nanomaterials for Magnetic and Optical Hyperthermia Applications

Nanomaterials for Magnetic and Optical Hyperthermia Applications
A Book

by Raluca Maria Fratila,Jesús Martínez De La Fuente

  • Publisher : Elsevier
  • Release : 2018-11-30
  • Pages : 384
  • ISBN : 0128139293
  • Language : En, Es, Fr & De
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Nanomaterials for Magnetic and Optical Hyperthermia Applications focuses on the design, fabrication and characterization of nanomaterials (magnetic, gold and hybrid magnetic-gold nanoparticles) for in vitro and in vivo hyperthermia applications, both as standalone and adjuvant therapy in combination with chemotherapy. The book explores the potential for more effective cancer therapy solutions through the synergistic use of nanostructured materials as magnetic and optical hyperthermia agents and targeted drug delivery vehicles, while also discussing the challenges related to their toxicity, regulatory and translational aspects. In particular, the book focuses on the design, synthesis, biofunctionalization and characterization of nanomaterials employed for magnetic and optical hyperthermia. This book will be an important reference resource for scientists working in the areas of biomaterials and biomedicine seeking to learn about the potential of nanomaterials to provide hyperthermia solutions. Explores the design of efficient nanomaterials for hyperthermia applications, allowing readers to make informed materials selection decisions Discusses the biofunctionalization of a range of nanomaterials and their interaction with living systems Provides an overview of the current clinical applications of nanomaterials in hyperthermia treatment

Advances and Challenges in Nanomedicine

Advances and Challenges in Nanomedicine
A Book

by Susan Hua,Sherry Y. Wu

  • Publisher : Frontiers Media SA
  • Release : 2019-02-28
  • Pages : 155
  • ISBN : 2889457451
  • Language : En, Es, Fr & De
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Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.

Cancer Nanotechnology

Cancer Nanotechnology
Principles and Applications in Radiation Oncology

by Sang Hyun Cho,Sunil Krishnan

  • Publisher : Taylor & Francis
  • Release : 2016-04-19
  • Pages : 284
  • ISBN : 1439878765
  • Language : En, Es, Fr & De
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Rapid advances in nanotechnology have enabled the fabrication of nanoparticles from various materials with different shapes, sizes, and properties, and efforts are ongoing to exploit these materials for practical clinical applications. Nanotechnology is particularly relevant in the field of oncology, as the leaky and chaotic vasculature of tumors—a hallmark of unrestrained growth—results in the passive accumulation of nanoparticles within tumors. Cancer Nanotechnology: Principles and Applications in Radiation Oncology is a compilation of research in the arena of nanoparticles and radiation oncology, which lies at the intersection of disciplines as diverse as clinical radiation oncology, radiation physics and biology, nanotechnology, materials science, and biomedical engineering. The book provides a comprehensive, cross-disciplinary survey of basic principles, research techniques, and outcomes with the goals of eventual clinical translation. Coverage includes A general introduction to fabrication, preferential tumor targeting, and imaging of nanoparticles The specific applications of nanomaterials in the realms of radiation therapy, hyperthermia, thermal therapy, and normal tissue protection from radiation exposure Outlooks for future research and clinical translation including regulatory issues for ultimate use of nanomaterials in humans Reflecting profound advances in the application of nanotechnology to radiation oncology, this comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. Along with various computational and experimental techniques, each chapter highlights the most promising approaches to the use of nanoparticles for radiation response modulation.

The Two Faces of Nanomaterials

The Two Faces of Nanomaterials
Toxicity and Bioactivity

by Dong-Wook Han,Timur Sh. Atabaev

  • Publisher : MDPI
  • Release : 2020-06-23
  • Pages : 146
  • ISBN : 3039289837
  • Language : En, Es, Fr & De
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Due to properties differing from those of larger materials, nanomaterials have been extensively used in different areas including nanomedicine, drug delivery, theragnosis, and bioimaging in recent years. Evaluating the toxicity profile (i.e., biocompatibility) of nanomaterials and their impact on health is essential to support the potential biomedical applications. This book deals with the two faces of nanomaterials, toxicity and bioactivity, hoping to aid with their development for clinical applications, reducing the possible risks associated with their use.