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Nanomedicine for Ischemic Cardiomyopathy

Nanomedicine for Ischemic Cardiomyopathy
Progress, Opportunities, and Challenges

by Morteza Mahmoudi

  • Publisher : Academic Press
  • Release : 2020-06
  • Pages : 258
  • ISBN : 012817434X
  • Language : En, Es, Fr & De
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Nanomedicine for Ischemic Cardiomyopathy: Progress, Opportunities, and Challenges provides an overview on the recent advances in diagnostic and treatment of ischemic cardiomyopathy diseases including myocardial infarction. Shortcomings of the current methods and how nanomedicine can address those obstacles in the field are discussed including the limitations of newly developed cell therapy approaches to clinical translation and how nanomedicine may overcome crucial issues and facilitate the successful and efficient clinical translation of cell therapy. Biomolecular therapy is also explored as another powerful approach for regeneration of heart tissue including available methods and systematic delivery of biomolecules using nanocarriers to the injured part of myocardium through active targeting. Finally, coverage of major tissue engineering advances for myocardial regeneration, including use of epicardial nanostructured patches for regeneration of injured epicardium and the highly conductive patches for enhancing cross talks between the cardiomyocytes, is explored. This concise, yet rigorous coverage, of the field of cardiac nanotechnology outlines the innovative and necessary role of nanomedicine in regenerative medicine for cardiac repair allowing researchers, clinicians, and nanotechnologists to examine the strengths and limitations of current findings and predict future trends to advance the applications of nanotechnology in cardiovascular biomedical research.

Nanocolloids for Nanomedicine and Drug Delivery

Nanocolloids for Nanomedicine and Drug Delivery
A Book

by Stefano Leporatti

  • Publisher : MDPI
  • Release : 2019-01-17
  • Pages : 272
  • ISBN : 3038974277
  • Language : En, Es, Fr & De
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This book is a printed edition of the Special Issue "Nanocolloids for Nanomedicine and Drug Delivery" that was published in Nanomaterials

The Handbook of Nanomedicine

The Handbook of Nanomedicine
A Book

by Kewal K. Jain

  • Publisher : Humana Press
  • Release : 2017-03-20
  • Pages : 659
  • ISBN : 1493969668
  • Language : En, Es, Fr & De
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Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.

Heart Failure in the Child and Young Adult

Heart Failure in the Child and Young Adult
From Bench to Bedside

by John L Jefferies,Anthony C Chang,Joseph W Rossano,Robert E Shaddy,Jeffrey A Towbin

  • Publisher : Academic Press
  • Release : 2017-12-05
  • Pages : 824
  • ISBN : 0128026138
  • Language : En, Es, Fr & De
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Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation Combines cutting-edge research with current guidelines from the field

Heart and Toxins

Heart and Toxins
A Book

by Dr. Meenakshisundaram Sundaram Ramachandran

  • Publisher : Elsevier
  • Release : 2014-08-12
  • Pages : 668
  • ISBN : 0124165990
  • Language : En, Es, Fr & De
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The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins” Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging Enables you to manage multiple clinical cases of cardiovascular toxicity Outlined conclusions at the end of each chapter providing “key learning points” to help you organize the chapter’s details without losing insight

Cardiac Regeneration

Cardiac Regeneration
A Book

by Masaki Ieda,Wolfram-Hubertus Zimmermann

  • Publisher : Springer
  • Release : 2017-10-27
  • Pages : 274
  • ISBN : 3319561065
  • Language : En, Es, Fr & De
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This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Medical Nanotechnology and Nanomedicine

Medical Nanotechnology and Nanomedicine
A Book

by Harry F. Tibbals

  • Publisher : CRC Press
  • Release : 2010-09-29
  • Pages : 527
  • ISBN : 1439808767
  • Language : En, Es, Fr & De
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Considering the fluid nature of nano breakthroughs—and the delicate balance between benefits and consequences as they apply to medicine—readers at all levels require a practical, understandable base of information about these developments to take greatest advantage of them. Medical Nanotechnology and Nanomedicine meets that need by introducing non-experts to nanomedicine and its evolving organizational infrastructure. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects—an ideal foundation upon which to plan and make decisions. Covers the use of nanotechnology in medical applications including imaging, diagnosis and monitoring, drug delivery systems, surgery, tissue regeneration, and prosthetics Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Organized by historical perspective, current status, and future prospects, this powerful book: Explores background, definitions and terms, and recent trends and forces in nanomedicine Surveys the landscape of nanomedicine in government, academia, and the private sector Reviews projected future directions, capabilities, sustainability, and equity of nanomedicine, and choices to be made regarding its use Includes graphical illustrations, references, and keywords to reinforce concepts and aid further research In its assessment of alternative and sometimes conflicting concepts proposed for the application of nanotechnology to medicine, this book surveys major initiatives and the work of leading labs and innovators. It uses informative examples and case summaries to illustrate proven accomplishments and imagined possibilities in research and development.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
A Book

by Bharat B. Aggarwal,Young-Joon Surh,S. Shishodia

  • Publisher : Springer Science & Business Media
  • Release : 2007-08-06
  • Pages : 490
  • ISBN : 0387464018
  • Language : En, Es, Fr & De
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The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy

Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy
A Book

by Challa S.S.R. Kumar

  • Publisher : Springer Nature
  • Release : 2019-11-22
  • Pages : 464
  • ISBN : 3662595966
  • Language : En, Es, Fr & De
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Ninth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Mesenchymal Stem Cell Derived Exosomes

Mesenchymal Stem Cell Derived Exosomes
The Potential for Translational Nanomedicine

by Yaoliang Tang,Buddhadeb Dawn

  • Publisher : Academic Press
  • Release : 2015-09-02
  • Pages : 288
  • ISBN : 0128004975
  • Language : En, Es, Fr & De
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Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Applications of Biotechnology in Cardiovascular Therapeutics

Applications of Biotechnology in Cardiovascular Therapeutics
A Book

by Kewal K. Jain

  • Publisher : Springer Science & Business Media
  • Release : 2011-07-25
  • Pages : 350
  • ISBN : 9781617792403
  • Language : En, Es, Fr & De
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For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.

Tissue Regeneration

Tissue Regeneration
A Book

by Hussein Abdelhay Essayed Kaoud

  • Publisher : BoD – Books on Demand
  • Release : 2018-06-06
  • Pages : 206
  • ISBN : 1789232600
  • Language : En, Es, Fr & De
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Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnology
Innovation and Production, 2 Volumes

by Jean Cornier

  • Publisher : John Wiley & Sons
  • Release : 2017-02-06
  • Pages : 775
  • ISBN : 3527340548
  • Language : En, Es, Fr & De
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With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

New Trends in Vascular Inflammation Research: From Biology to Therapy

New Trends in Vascular Inflammation Research: From Biology to Therapy
A Book

by Masanori Aikawa,Ichiro Manabe,Nikolaus Marx

  • Publisher : Frontiers Media SA
  • Release : 2019-10-17
  • Pages : 329
  • ISBN : 2889456374
  • Language : En, Es, Fr & De
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Exposure to Engineered Nanomaterials in the Environment

Exposure to Engineered Nanomaterials in the Environment
A Book

by Nelson Marmiroli,Jason C. White,Jing Song

  • Publisher : Elsevier
  • Release : 2019-05-28
  • Pages : 362
  • ISBN : 0128148365
  • Language : En, Es, Fr & De
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Exposure to Engineered Nanomaterials in the Environment provide a new, holistic framework for testing and evaluating the potential benefits and risks of engineered nanomaterials (ENMs), including their potential socioeconomic impacts, ethical issues and consumers’ expectations and fears. The book covers nanomaterial presence in various environments, agroecosystems and other areas within the human sphere of actions. The book includes sections on (i) Chemical, physical and biological properties, (ii) Presence and diffusion of ENMs in human environments, agriculture, food and drug products, (iii) ENMs as a pillar in biological and medical research, and (iv) Social and regulatory issues emerging from years of application. The book is designed to increase awareness to key end-users and stakeholders, including food producers and processors, industry, representatives of society and consumers, and those looking to implement an accurate and effective risk analysis procedure that promotes the sustainable use of nanotechnology. Assesses both the positive and negative impacts of engineered nanomaterials in the environment Shows how engineered nanomaterials are used in agricultural environments, food products, drugs and cosmetics Discusses the unique properties of a range of engineered nanomaterials that lead to their environmental effects

Biomedical Applications of Nanotechnology

Biomedical Applications of Nanotechnology
A Book

by Vinod Labhasetwar,Diandra L. Leslie-Pelecky

  • Publisher : John Wiley & Sons
  • Release : 2007-09-28
  • Pages : 272
  • ISBN : 9780470152911
  • Language : En, Es, Fr & De
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An overview of nanotechnology and its potential The field of nanotechnology is undergoing rapid developments on many fronts. This reference provides a comprehensive review of various nanotechnologies with a view to their biomedical applications. With chapters contributed by distinguished scientists from diverse disciplines, Biomedical Applications of Nanotechnology : Reviews recent advances in the designing of various nanotechnologies based on nucleic acids, polymers, biomaterials, and metals Discusses biomedical nanotechnology in areas such as drug and gene delivery Covers advanced aspects of imaging and diagnostics Includes a chapter on the issue of nanotoxicology Complete with figures and tables, this is a practical, hands-on reference book for researchers in pharmaceutical and biotech industries, biomedical engineers, pharmaceutical scientists, pharmacologists, and materials scientists as well as for the policymakers who need to understand the potential of nanotechnology. It is also an excellent resource book for graduate-level students in pharmaceutical sciences, biomedical engineering, and other fields in which nanotechnology is playing an increasingly important role.

4th European Conference of the International Federation for Medical and Biological Engineering 23 - 27 November 2008, Antwerp, Belgium

4th European Conference of the International Federation for Medical and Biological Engineering 23 - 27 November 2008, Antwerp, Belgium
A Book

by Jos van der Sloten,Pascal Verdonck,Marc Nyssen,Jens Haueisen

  • Publisher : Springer
  • Release : 2008-12-08
  • Pages : 2808
  • ISBN : 9783540892076
  • Language : En, Es, Fr & De
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The 4th European Congress of the International Federation for Medical and Biological Federation was held in Antwerp, November 2008. The scientific discussion on the conference and in this conference proceedings include the following issues: Signal & Image Processing ICT Clinical Engineering and Applications Biomechanics and Fluid Biomechanics Biomaterials and Tissue Repair Innovations and Nanotechnology Modeling and Simulation Education and Professional

Nanotechnology

Nanotechnology
The Future is Tiny

by Michael Berger

  • Publisher : Royal Society of Chemistry
  • Release : 2016-08-18
  • Pages : 350
  • ISBN : 1782625267
  • Language : En, Es, Fr & De
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Nanotechnology: The Future is Tiny introduces 176 different research projects from around the world that are exploring the different areas of nanotechnologies. Using interviews and descriptions of the projects, the collection of essays provides a unique commentary on the current status of the field. From flexible electronics that you can wear to nanomaterials used for cancer diagnostics and therapeutics, the book gives a new perspective on the current work into developing new nanotechnologies. Each chapter delves into a specific area of nanotechnology research including graphene, energy storage, electronics, 3D printing, nanomedicine, nanorobotics as well as environmental implications. Through the scientists' own words, the book gives a personal perspective on how nanotechnologies are created and developed, and an exclusive look at how today's research will create tomorrow's products and applications. This book will appeal to anyone who has an interest in the research and future of nanotechnology.

Handbook of Low-Level Laser Therapy

Handbook of Low-Level Laser Therapy
A Book

by Michael R. Hamblin,Tanupriya Agrawal,Marcelo de Sousa

  • Publisher : CRC Press
  • Release : 2016-10-14
  • Pages : 1170
  • ISBN : 1315341174
  • Language : En, Es, Fr & De
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Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world’s leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.

Protein-Nanoparticle Interactions

Protein-Nanoparticle Interactions
The Bio-Nano Interface

by Masoud Rahman,Sophie Laurent,Nancy Tawil,L'Hocine Yahia,Morteza Mahmoudi

  • Publisher : Springer Science & Business Media
  • Release : 2013-06-24
  • Pages : 86
  • ISBN : 3642375553
  • Language : En, Es, Fr & De
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In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.