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Nanomedicines for Breast Cancer Theranostics

Nanomedicines for Breast Cancer Theranostics
A Book

by Nanasaheb D. Thorat,Joanna Bauer

  • Publisher : Elsevier
  • Release : 2020-03-08
  • Pages : 438
  • ISBN : 0128200170
  • Language : En, Es, Fr & De
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Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

Targeted Nanomedicine for Breast Cancer Therapy

Targeted Nanomedicine for Breast Cancer Therapy
A Book

by Shivani Rai Paliwal,Rishi Paliwal

  • Publisher : Academic Press
  • Release : 2021-11-29
  • Pages : 590
  • ISBN : 9780128244760
  • Language : En, Es, Fr & De
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Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of different and diverse aspects of treatment approaches for breast cancer such as conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. Worldwide, breast cancer is the most common cancer in women; however, breast cancer therapy is always challenging. Reports and new studies are released from different corners of the world and it is interdisciplinary research. This book compiles the most important information on the state-of-the-art breast cancer therapeutics. It contains detailed information on breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, the first part describes basic and receptor mediated targeting approaches and the second part examines tumor microenvironment mediated approaches. Targeted Nanomedicine for Breast Cancer Therapy is a useful book for pharmaceutical scientists, basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry. Highlights promising breast cancer targets to help design nanomedicines and stimuli-triggered methods for cancer imaging and treatment Provides in-depth exploration of targeted breast cancer therapy as well as highlights to understand the most important points quickly Explores cutting edge research in the area of targeted nanomedicine and drug delivery including nanotheranostics for breast cancer therapy

Advanced Theranostic Nanomedicine in Oncology

Advanced Theranostic Nanomedicine in Oncology
A Book

by Gianni Ciofani,Attilio Marino,Christos Tapeinos

  • Publisher : Frontiers Media SA
  • Release : 2020-03-18
  • Pages : 329
  • ISBN : 2889636216
  • Language : En, Es, Fr & De
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Nanomedicine for Cancer Therapy

Nanomedicine for Cancer Therapy
From Chemotherapeutic to Hyperthermia-Based Therapy

by Piyush Kumar,Rohit Srivastava

  • Publisher : Springer
  • Release : 2016-11-21
  • Pages : 68
  • ISBN : 3319458264
  • Language : En, Es, Fr & De
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This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.

Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer
A Book

by Malay K. Das

  • Publisher : Academic Press
  • Release : 2021-03-26
  • Pages : 426
  • ISBN : 0128217006
  • Language : En, Es, Fr & De
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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications
A Book

by Prakash Rai,Stephanie A. Morris

  • Publisher : Springer
  • Release : 2018-11-12
  • Pages : 480
  • ISBN : 3030017753
  • Language : En, Es, Fr & De
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This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Cancer Nanotheranostics: What Have We Learned So Far?

Cancer Nanotheranostics: What Have We Learned So Far?

by João Conde,Pedro Viana Baptista,Jesús M De La Fuente,Furong Tian

  • Publisher : Frontiers Media SA
  • Release : 2016-03-17
  • Pages : 329
  • ISBN : 288919776X
  • Language : En, Es, Fr & De
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After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.

Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine

Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine
A Book

by Yusuf Tutar

  • Publisher : Bentham Science Publishers
  • Release : 2020-06-08
  • Pages : 198
  • ISBN : 9811456895
  • Language : En, Es, Fr & De
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Nanotheranostics is a recent medical field which integrates diagnostic imaging protocols and therapeutic functions to monitor real time drug release in the body and distribution to the target site. The combined processes allow technicians to observe the effectiveness of a specifically designed drug candidate and predict its possible side effects. All these features help clinicians in optimizing treatment options for cancer and other diseases for the individual patient. Current research is tailored to individual therapy because each drug may display a variety of responses depending on variations in an individual’s genetics and subsequently, their clinical biochemistry. Many tumors are still challenging for therapists in terms of available treatment and nanotheranostic strategies may help them to combat cancer more efficiently. Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine presents information about current theranostic technologies in use at clinics and recent research on nanotheranostic applications, with a focus on cancer treatment. Information is presented in seven organized chapters that cover the basics of cancer nanotheranostics, tumor microenvironmental factors, gene therapy and gene delivery concepts, and the combined application of diagnostic imaging with cancer chemotherapy. A chapter focusing on the role of non-coding MRNAs in breast cancer carcinogenesis is also included, giving readers a glimpse of the complexities in the molecular biology of cancer which drive the need for new theranostic technologies. The book is of interest to medical professionals (including oncologists and specialists in internal medicine), diagnostic imaging technicians, and researchers in the fields of pharmacology, molecular biology and nuclear medicine.

Nanomedicines

Nanomedicines
Design, Delivery and Detection

by Martin Braddock

  • Publisher : Royal Society of Chemistry
  • Release : 2016-04-28
  • Pages : 370
  • ISBN : 1849739471
  • Language : En, Es, Fr & De
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This book will provide an overview of the chemistry of nanocarrier design and the considerations that need to be made when developing a nanomedicine.

Intracellular Delivery III

Intracellular Delivery III
Market Entry Barriers of Nanomedicines

by Aleš Prokop,Volkmar Weissig

  • Publisher : Springer
  • Release : 2016-10-31
  • Pages : 453
  • ISBN : 3319435256
  • Language : En, Es, Fr & De
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A critical review is attempted to assess the status of nanomedicine entry onto the market. The emergence of new potential therapeutic entities such as DNA and RNA fragments requires that these new “drugs” will need to be delivered in a cell-and organelle-specific manner. Although efforts have been made over the last 50 years or so to develop such delivery technology, no effective and above all clinically approved protocol for cell-specific drug delivery in humans exists as yet. Various particles, macromolecules, liposomes and most recently “nanomaterials” have been said to “show promise” but none of these promises have so far been “reduced” to human clinical practice. The focus of this volume is on cancer indication since the majority of published research relates to this application; within that, we focus on solid tumors (solid malignancies). Our aim is critically to evaluate whether nanomaterials, both non-targeted and targeted to specific cells, could be of therapeutic benefit in clinical practice. The emphasis of this volume will be on pharmacokinetics (PK) and pharmacodynamics (PD) in animal and human studies. Apart from the case of exquisitely specific antibody-based drugs, the development of target-specific drug–carrier delivery systems has not yet been broadly successful at the clinical level. It can be argued that drugs generated using the conventional means of drug development (i.e., relying on facile biodistribution and activity after (preferably) oral administration) are not suitable for a target-specific delivery and would not benefit from such delivery even when a seemingly perfect delivery system is available. Therefore, successful development of site-selective drug delivery systems will need to include not only the development of suitable carriers, but also the development of drug entities that meet the required PK/PD profile.

Post-genomic Approaches in Cancer and Nano Medicine

Post-genomic Approaches in Cancer and Nano Medicine

by Kishore R. Sakharkar,Meena K. Sakharkar, Ramesh Chandra

  • Publisher : River Publishers
  • Release : 2015-04-11
  • Pages : 384
  • ISBN : 8793102860
  • Language : En, Es, Fr & De
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Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers. This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: Alternative splicing and cancerCancer imagingNanomaterials in infectious diseasesNanomedicine in oxidative stress and cancerNanoparticle based drug delivery systems

Multifunctional Nanocarriers for Contemporary Healthcare Applications

Multifunctional Nanocarriers for Contemporary Healthcare Applications
A Book

by Barkat, Md. Abul,A.B., Harshita,Beg, Sarwar,Ahmad, Farhan J.

  • Publisher : IGI Global
  • Release : 2018-01-12
  • Pages : 602
  • ISBN : 1522547827
  • Language : En, Es, Fr & De
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Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

Journal of Nano Research

Journal of Nano Research
A Book

by Efstathios I. Meletis

  • Publisher : Trans Tech Publications Ltd
  • Release : 2019-08-27
  • Pages : 188
  • ISBN : 3035731780
  • Language : En, Es, Fr & De
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The 59th volume of the "Journal of Nano Research" contains peer-reviewed papers by the results of the research from the field of synthesis and properties of various nanomaterials and nanostructures for the biomedical and industrial application. We hope that this volume of the journal will be useful and interesting for a wide range of engineers, scientists, and students whose activity is related with the creation and using of nanomaterials and nanotechnologies in different branches of human activity.

Cancer: New Insights for the Healthcare Professional: 2011 Edition

Cancer: New Insights for the Healthcare Professional: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 3937
  • ISBN : 1464900027
  • Language : En, Es, Fr & De
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Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Handbook of Personalized Medicine

Handbook of Personalized Medicine
Advances in Nanotechnology, Drug Delivery, and Therapy

by Ioannis S. Vizirianakis

  • Publisher : CRC Press
  • Release : 2014-02-12
  • Pages : 1560
  • ISBN : 9814411191
  • Language : En, Es, Fr & De
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This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Korea

Korea
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2014
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Applications of Biophotonics and Nanobiomaterials in Biomedical Engineering

Applications of Biophotonics and Nanobiomaterials in Biomedical Engineering
A Book

by Mohammad E. Khosroshahi

  • Publisher : CRC Press
  • Release : 2017-10-30
  • Pages : 500
  • ISBN : 149874849X
  • Language : En, Es, Fr & De
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This book provides a link between different disciplines of nanophysics, biophotonics, nanobiomaterials & applications of nanobiophotonics in biomedical research and engineering. The fundamentals of light, matter, nanobiomaterials & nanophysics are discussed together, and relevant applications in biomedical engineering as well as other related factors influencing the interaction process are explicated. Theoretical and experimental research is combined, emphasizing the influence of crucial common factors on applications.

Molecular Imaging in Oncology

Molecular Imaging in Oncology
A Book

by Otmar Schober,Fabian Kiessling,Jürgen Debus

  • Publisher : Springer Nature
  • Release : 2020-06-27
  • Pages : 918
  • ISBN : 3030426181
  • Language : En, Es, Fr & De
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This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit all readers who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.

Anthracyclines—Advances in Research and Application: 2013 Edition

Anthracyclines—Advances in Research and Application: 2013 Edition
ScholarlyPaper

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2013-06-21
  • Pages : 36
  • ISBN : 1481672789
  • Language : En, Es, Fr & De
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Anthracyclines—Advances in Research and Application: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Anthracyclines—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Anthracyclines—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

World Congress on Medical Physics and Biomedical Engineering 2018

World Congress on Medical Physics and Biomedical Engineering 2018
June 3-8, 2018, Prague, Czech Republic

by Lenka Lhotska,Lucie Sukupova,Igor Lacković,Geoffrey S. Ibbott

  • Publisher : Springer
  • Release : 2018-07-26
  • Pages : 888
  • ISBN : 9811090238
  • Language : En, Es, Fr & De
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This book (vol. 3) presents the proceedings of the IUPESM World Congress on Biomedical Engineering and Medical Physics, a triennially organized joint meeting of medical physicists, biomedical engineers and adjoining health care professionals. Besides the purely scientific and technological topics, the 2018 Congress will also focus on other aspects of professional involvement in health care, such as education and training, accreditation and certification, health technology assessment and patient safety. The IUPESM meeting is an important forum for medical physicists and biomedical engineers in medicine and healthcare learn and share knowledge, and discuss the latest research outcomes and technological advancements as well as new ideas in both medical physics and biomedical engineering field.