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Nanotechnology Based Approaches for Tuberculosis Treatment

Nanotechnology Based Approaches for Tuberculosis Treatment
A Book

by Prashant Kesharwani

  • Publisher : Academic Press
  • Release : 2020-06-10
  • Pages : 284
  • ISBN : 0128226110
  • Language : En, Es, Fr & De
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Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy
A Book

by Rajan Mariappan

  • Publisher : Academic Press
  • Release : 2021-03-29
  • Pages : 326
  • ISBN : 0128244844
  • Language : En, Es, Fr & De
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A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine. Features the most notable uses of drug for tuberculosis treatment, including novel advances in materials Assesses new agents and chemical compounds against tuberculosis Examines the interaction of new technologies to discover ways to treat tuberculosis more effectively and efficiently

Macro, Micro, and Nano-Biosensors

Macro, Micro, and Nano-Biosensors
Potential Applications and Possible Limitations

by Mahendra Rai,Anatoly Reshetilov,Yulia Plekhanova,Avinash P Ingle

  • Publisher : Springer Nature
  • Release : 2021-01-04
  • Pages : 415
  • ISBN : 3030554902
  • Language : En, Es, Fr & De
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This book includes an international group of researchers who present the latest achievements in the field of enzyme, immune system, and microbial and nano-biosensors. It highlights the experimental evidence for formation of biological fuel cells (BFCs)-which has a dual purpose – as a device that produces electricity and the systems which produce it simultaneously cleaning up the environment from polluting organic compounds. Considering the work in the field of macro, micro and nano-biosensors, considerable attention is paid to the use of nanomaterials for the modification of working electrodes. Nanomaterials in some cases can significantly improve the parameters of analytical systems. Readers will be interested in the projection of the presented theoretical and experimental materials in the field of practical application of modern analytical developments. The presented results in many cases imply the possibility of using the created models of macro, micro and nano-biosensors, and biofuel elements in the field of health, and protection/restoration of the environment. It includes information about all existing types of transducers of signals in biosensors – electrochemical, optical and quantum-optics, thermoelectric, data of atomic force microscopy, piezoelectric, and more. On the basis of these principles, descriptions are given about the functioning of macro, micro and nano- biosensors for the detection of compounds used in medicine, detection of compounds that clog the environment, and thus affect human health, for compounds that are potentially the basis for the production of drugs, for the selection of compounds that have medicinal activity, for immunodetection, and to assess the quality of food. These questions form the basis of research carried out in the field of biosensors in the world. Since the described models of biosensors have high sensitivity, high measurement speed and selectivity, the described results attract the attention of both the ordinary reader and business class specialists who create and implement analytical technologies. This book is very useful for researchers in life sciences, chemical sciences, physics, and engineering. In addition, it will be useful for the persons working in industry. Advanced technologies specialists will be attracted by the novelty of the proposed solutions and their relevance and ease of implementation. Since the studies contain sections describing the parameters of different biosensors, BFCs, they are easily navigated into assessing the effectiveness of the practical use of the proposed device. The relevant sections indicate such characteristics as detection ranges, life span, type of biological material used, the method of formation of the bio-receptor part. These parameters are of interest to both developers of new models of biosensors and BFC, and their manufacturers.

Nano Medicine and Nano Safety

Nano Medicine and Nano Safety
Recent Trends and Clinical Evidences

by Malay K. Das,Yashwant V. Pathak

  • Publisher : Springer Nature
  • Release : 2020-12-09
  • Pages : 635
  • ISBN : 9811562555
  • Language : En, Es, Fr & De
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This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.

Nanotechnology for Infectious Diseases

Nanotechnology for Infectious Diseases
A Book

by Saif Hameed

  • Publisher : Springer Nature
  • Release : 2022
  • Pages : 129
  • ISBN : 9811691908
  • Language : En, Es, Fr & De
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Handbook of Lung Targeted Drug Delivery Systems

Handbook of Lung Targeted Drug Delivery Systems
Recent Trends and Clinical Evidences

by Yashwant Pathak,Nazrul Islam

  • Publisher : CRC Press
  • Release : 2021-10-17
  • Pages : 692
  • ISBN : 1000450767
  • Language : En, Es, Fr & De
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Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems

Green Synthesis in Nanomedicine and Human Health

Green Synthesis in Nanomedicine and Human Health
A Book

by Richard L. K. Glover,Daniel Nyanganyura,Rofhiwa Bridget Mulaudzi,Maluta Steven Mufamadi

  • Publisher : CRC Press
  • Release : 2021-03-10
  • Pages : 322
  • ISBN : 100035119X
  • Language : En, Es, Fr & De
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Green synthesis is an emerging method for deriving nanoparticles present in natural plants for use in nanomedicine. Written by experts in the field, Green Synthesis in Nanomedicine and Human Health showcases the exciting developments of this specialty and its potential for promoting human health and well-being. This book gives practical information on novel preparation methods for identifying nanoparticles present in natural plants. It discusses applications of nanoparticles in combating communicable, non-communicable and vector-borne diseases. It also explores the potential for nanoparticles to combat antimicrobial resistance through improvements in treatment methods, diagnostics and drug delivery systems. Features scientific evidence of opportunities for integrating indigenous flora into nanomedicine to develop cost-effective therapeutic and diagnostic solutions for diseases, including cancer, tuberculosis, malaria and diabetes. Places green synthesis and nanomedicine in the African orthodox and traditional healthcare context. Provides policymakers with scientific evidence to inform policies for controlling or mitigating dangerous diseases. This book is essential reading for students, scientists, policymakers and practitioners of nanotechnology, and will appeal to anyone with an interest in integrating traditional African healthcare and Western medicine.

Bio-Nano Interface

Bio-Nano Interface
Applications in Food, Healthcare and Sustainability

by Manoranjan Arakha,Arun Kumar Pradhan,Suman Jha

  • Publisher : Springer Nature
  • Release : 2021-11-27
  • Pages : 355
  • ISBN : 9811625166
  • Language : En, Es, Fr & De
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This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions. It describes the consequences of these interactions on other biological aspects like flora and fauna of the niche, cell proliferation, etc. The book provides information about the novel and eco-friendly nanoparticle synthesis methods, such as continuous synthesis of nanoparticles using microbial cells. Additionally, the book discusses nanoparticles' potential impact in different areas of biological sciences like food, medicine, agriculture, and the environment. Due to their advanced physicochemical properties, nanoparticles have revolutionized biomedical and pharmaceutical sciences. Inside the biological milieu, nanoparticles interact with different moieties to adopt stable shape, size, and surface functionalities and form nano-biomolecular complexes. The interaction pattern at the interface form complexes determines the fate of interacting biomolecules and nanoparticles inside the biological system. Understanding the interaction pattern at the nano-bio interface is crucial for the safe use of nanoparticles in natural sciences. This book rightly addresses all questions about the interaction and the ensuing structure and function of these nano-biomolecular complexes. This book caters to students and researchers in the area of biotechnology, microbiology, and pharmaceutical sciences.

Nanoformulations in Human Health

Nanoformulations in Human Health
Challenges and Approaches

by Sushama Talegaonkar,Mahendra Rai

  • Publisher : Springer Nature
  • Release : 2020-07-31
  • Pages : 548
  • ISBN : 3030418588
  • Language : En, Es, Fr & De
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This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing of novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers etc. The most important aspect of the book covers various types of nanoformulations and their applications in treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, skin cancer, arthritis and tuberculosis.

Medicinal Plants for Lung Diseases

Medicinal Plants for Lung Diseases
A Pharmacological and Immunological Perspective

by Kamal Dua,Srinivas Nammi,Dennis Chang,Dinesh Kumar Chellappan,Gaurav Gupta,Trudi Collet

  • Publisher : Springer Nature
  • Release : 2021-07-30
  • Pages : 622
  • ISBN : 9813368500
  • Language : En, Es, Fr & De
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This book summarizes experimentally-supported research on the therapeutic efficacy of plant extracts and their constituents on a range of respiratory diseases including infections. It discusses the pharmacological, cellular and molecular factors involved in the pathogenies of respiratory diseases and their modulation by plant-derived compounds. Additionally, it underlines the growing relevance of medicinal plant-based advanced drug delivery systems for treating lung diseases providing maximal therapeutic efficacy with better patient compliance. Overall, this comprehensive book is a blend of translational, biological, chemical and drug delivery aspects of medicinal plants employed in targeting respiratory diseases and attracts a range of audiences including physiochemist, translational and clinical researchers working in the field of respiratory diseases.

Nanocarriers for the Delivery of Combination Drugs

Nanocarriers for the Delivery of Combination Drugs
A Book

by Sanjula Baboota,Javed Ali

  • Publisher : Elsevier
  • Release : 2021-05-18
  • Pages : 540
  • ISBN : 0128209402
  • Language : En, Es, Fr & De
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Nanocarriers for the Delivery of Combination Drugs focuses on the role of nanocarriers in the delivery of combination drugs for the management and treatment of various diseases. Nanocarriers belonging to the category of polymeric nanoparticles, dendrimers, lipidic nanocarriers (like nanoemulsions), liposomes, solid lipid nanoparticles, nanostructured lipid carriers are now being used in the drug delivery of combination drugs. This book helps readers assimilate all the information available surrounding the application of various nanocarrier technologies for the delivery of combination drugs of synthetic and natural origin, including small and large molecules. This is an important reference source for pharmaceutical scientists and biomaterials scientists who are looking to gain an increased understanding on how nanotechnology is improving the efficiency of combination drug delivery. Outlines how nanocarriers are used to enhance combination drug delivery systems Assesses the major challenges of delivering combination drugs successfully, and explains how nanocarriers can help meet these challenges Explores the characteristics of a variety of nanocarrier material types

Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions
A Book

by Seyed Ehtesham Hasnain,Nasreen Z. Ehtesham,Sonam Grover

  • Publisher : Springer Nature
  • Release : 2019-11-30
  • Pages : 514
  • ISBN : 9813294132
  • Language : En, Es, Fr & De
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This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.

Nanomedical Drug Delivery for Neurodegenerative Diseases

Nanomedical Drug Delivery for Neurodegenerative Diseases
A Book

by Awesh K. Yadav,Rahul Shukla,S.J.S. Flora

  • Publisher : Academic Press
  • Release : 2022-03-10
  • Pages : 282
  • ISBN : 0323898017
  • Language : En, Es, Fr & De
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Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. Includes design, synthesis and applications of drug delivery systems Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems Details how nanocarrier-based delivery is useful to improve efficacy and cure

Intellectual Property Issues in Nanotechnology

Intellectual Property Issues in Nanotechnology
A Book

by Chetan Keswani

  • Publisher : CRC Press
  • Release : 2020-09-08
  • Pages : 394
  • ISBN : 1000091333
  • Language : En, Es, Fr & De
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Intellectual Property Issues in Nanotechnology focuses on the integrated approach for sustained innovation in various areas of nanotechnology. The theme of this book draws to a great extent on the industrial and socio-legal implications of intellectual property rights for nanotechnology-based advances. The book takes a comprehensive look not only at the role of intellectual property rights in omics-based research but also at the ethical and intellectual standards and how these can be developed for sustained innovation. This book attempts to collate and organize information on current attitudes and policies in several emerging areas of nanotechnology. Adopting a unique approach, this book integrates science and business for an inside view of the industry. Peering behind the scenes, it provides a thorough analysis of the foundations of the present day industry for students and professionals alike.

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes
A Book

by Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer

  • Publisher : Academic Press
  • Release : 2017-05-23
  • Pages : 552
  • ISBN : 0128097183
  • Language : En, Es, Fr & De
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Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

New Approaches Against Drug-Resistant M. tuberculosis

New Approaches Against Drug-Resistant M. tuberculosis
A Book

by Maria Rosalia Pasca,Yossef Av-Gay,Giorgia Mori

  • Publisher : Frontiers Media SA
  • Release : 2021-06-09
  • Pages : 129
  • ISBN : 288966869X
  • Language : En, Es, Fr & De
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Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer

Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer
A Book

by Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik

  • Publisher : IGI Global
  • Release : 2021-02-12
  • Pages : 559
  • ISBN : 1799850501
  • Language : En, Es, Fr & De
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Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Integrating Biologically-Inspired Nanotechnology into Medical Practice

Integrating Biologically-Inspired Nanotechnology into Medical Practice
A Book

by Nayak, B.K.,Nanda, Anima,Bhat, M. Amin

  • Publisher : IGI Global
  • Release : 2016-09-07
  • Pages : 394
  • ISBN : 152250611X
  • Language : En, Es, Fr & De
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Nanotechnology has grown in its use and adoption across sectors. In particular, the medical field has identified the vast opportunities nanotechnology presents, especially for earlier disease detection and diagnosis versus traditional methods. Integrating Biologically-Inspired Nanotechnology into Medical Practice presents the latest research on nanobiotechnology and its application as a real-world healthcare solution. Emphasizing applications of micro-scale technologies in the areas of oncology, food science, and pharmacology, this reference publication is an essential resource for medical professionals, researchers, chemists, and graduate-level students in the medical and pharmaceutical sciences.

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics
A Book

by Alexandru Mihai Grumezescu

  • Publisher : William Andrew
  • Release : 2017-05-03
  • Pages : 372
  • ISBN : 0323527264
  • Language : En, Es, Fr & De
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Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment. Explores the benefits of using a variety of nanomaterials as drug delivery agents Explains how nanocarriers can reduce the side effects of therapeutic agents Provides an analysis of the pros and cons of using specific nanocarriers to solve particular diagnosis and delivery problems

Nanotechnology and Drug Delivery, Volume Two

Nanotechnology and Drug Delivery, Volume Two
Nano-Engineering Strategies and Nanomedicines against Severe Diseases

by Jose L. Arias

  • Publisher : CRC Press
  • Release : 2016-04-21
  • Pages : 487
  • ISBN : 1482262738
  • Language : En, Es, Fr & De
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The recent introduction of nanomedicines in the drug therapy arena is revolutionizing the management of severe diseases. The key advance in the field is the optimization of the biological fate of drug molecules, thus improving the therapeutic effect while keeping to a very minimum the associated toxicity. Volume one of this book series, Nanoplatforms in Drug Delivery, established the basic aspects in the development of drug-loaded nanoplatforms, the so-called nanomedicines or nanodrugs, focusing on representative materials and strategies used in their formulation. Taking advantage of the advanced conceptualizations on nanomedicine engineering that were described in volume one, volume two, Nano-Engineering Strategies and Nanomedicines against Severe Diseases, analyzes in depth special features related to the formulation of nanoplatforms for oral, dental, topical and transdermal, pulmonary and nasal, ocular and otic, vaginal, and brain drug delivery and targeting. Particular aspects of nanomedicine engineering and in vivo fate associated with the routing of drug administration are given special attention. In addition, an up-to-date view is presented on the use of nanomedicines against severe diseases, such as cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, and metabolic diseases. The chapters analyze the key factors that need to be controlled to achieve the optimum therapeutic effect. Attention is further given to gene delivery and the recent concept of nanotheranosis.