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Neurobiology of Alcohol and the Brain

Neurobiology of Alcohol and the Brain
A Book

by Ashok K. Singh

  • Publisher : Academic Press
  • Release : 2020-10-01
  • Pages : 364
  • ISBN : 0128198915
  • Language : En, Es, Fr & De
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Neurobiology of Alcohol and the Brain addresses addiction related problems, reviewing both mechanisms and withdrawal systems surrounding alcohol addiction. Chapters discuss mechanisms of rewarding, aversive effects, alcohol’s interaction with other drugs (and ensuing adverse consequences), and current and novel treatments. Lastly, the reader is provided with examples of an experimental study that describes the possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Behavioral Neurobiology of Alcohol Addiction

Behavioral Neurobiology of Alcohol Addiction
A Book

by Wolfgang Sommer,Rainer Spanagel

  • Publisher : Springer Science & Business Media
  • Release : 2012-07-28
  • Pages : 727
  • ISBN : 3642287204
  • Language : En, Es, Fr & De
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The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.

Neuroscience: Pathways to Alcohol Dependence: Part I -- Overview of the Neurobiology of Dependence

Neuroscience: Pathways to Alcohol Dependence: Part I -- Overview of the Neurobiology of Dependence
A Reprint from the Journal, "Alcohol Research and Health"

by Edith V. Sullivan

  • Publisher : Unknown Publisher
  • Release : 2009-05
  • Pages : 283
  • ISBN : 9781437913620
  • Language : En, Es, Fr & De
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Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models; Laser-Assisted Microdissection; Proteomic Solutions for Analytical Challenges Associated with Alcohol Research; On the Use of Short-Interfering RNA to Study Alcohol-Related Genes; Viral Delivery of Small-Hairpin RNAs for Reducing Gene Expression in the Rodent Brain; Quantitative Trait Locus Analysis: Multiple Cross and Heterogeneous Stock Mapping; Interval-Specific Congenic Animals for High-Resolution Quantitative Trait Loci Mapping; Single-Nucleotide Polymorphism Masking; Expression Quantitative Trait Loci and the PhenoGen Database; Integrative Genetic Analysis of Alcohol Dependence; Using the GeneNetwork Web Resources; Conclusions; Glossary. Illus.

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence
A Book

by Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe

  • Publisher : Elsevier
  • Release : 2014-05-02
  • Pages : 566
  • ISBN : 0124071554
  • Language : En, Es, Fr & De
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Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available

Neurobiology of Alcohol Abuse

Neurobiology of Alcohol Abuse
A Book

by William J. Haugen Light

  • Publisher : Charles C Thomas Pub Limited
  • Release : 1986
  • Pages : 169
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Alcohol and the Nervous System

Alcohol and the Nervous System
A Book

by Edith V. Sullivan,Adolf Pfefferbaum

  • Publisher : Elsevier
  • Release : 2014-10-08
  • Pages : 704
  • ISBN : 0444626220
  • Language : En, Es, Fr & De
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Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Alcohol and Alcoholism

Alcohol and Alcoholism
Effects on Brain and Development

by John H. Hannigan,Linda P. Spear,Norman E. Spear,Charles R. Goodlett

  • Publisher : Psychology Press
  • Release : 1999-02-01
  • Pages : 304
  • ISBN : 1135683980
  • Language : En, Es, Fr & De
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This is the first volume that focuses on the lifespan neurobehavioral factors likely to determine susceptibility to alcohol abuse and its consequences. The chapters offer careful analysis of the effects of ethanol on the fetus, the infant, the adolescent, and the adult. The authors include behavioral neuroscientists and clinical neuropsychologists. Their topics range from the neurochemical and neuroanatomical consequences of prenatal alcohol to the cognitive consequences of prenatal alcohol on preschool and school-age children. The impact of genetics on sensitivity to alcohol is considered in terms of analytic tests using techniques of behavioral genetics and molecular biology. The consequences of exposure to alcohol during breastfeeding are described in experiments with human infants. The alcoholism that develops in adulthood is analyzed through the experimental study of relapse from alcohol deprivation and assessment of neuropsychological impairments and treatment for alcoholics. Drawing on extensive research that has applied techniques from molecular neurobiology and tests of learning and memory to the clinical assessment and treatment of alcoholics. The volume answers recent questions raised by the National Institute of Alcohol Abuse and Alcoholism and the National Institute of Drug Abuse about the role of early experience in susceptibility to later abuse of alcohol and other drugs. Although epidemiological studies can describe the problem, solutions in terms of mechanisms that mediate these effects will be found only with the kinds of experimentally oriented approaches the chapter authors describe.

Neuroscience of Alcohol

Neuroscience of Alcohol
Mechanisms and Treatment

by Victor R. Preedy

  • Publisher : Academic Press
  • Release : 2019-03-19
  • Pages : 736
  • ISBN : 0128131268
  • Language : En, Es, Fr & De
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Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Neurobiology of Addiction

Neurobiology of Addiction
A Book

by George F. Koob,Michel Le Moal

  • Publisher : Elsevier
  • Release : 2005-11-11
  • Pages : 504
  • ISBN : 0080497373
  • Language : En, Es, Fr & De
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Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain
A Book

by George F. Koob,Michael A. Arends,Michel Le Moal

  • Publisher : Academic Press
  • Release : 2014-07-12
  • Pages : 350
  • ISBN : 0123869595
  • Language : En, Es, Fr & De
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Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

The Pharmacology of Alcohol and Alcohol Dependence

The Pharmacology of Alcohol and Alcohol Dependence
A Book

by Henri Begleiter,Benjamin Kissin

  • Publisher : Oxford University Press on Demand
  • Release : 1996
  • Pages : 525
  • ISBN : 9780195100945
  • Language : En, Es, Fr & De
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This reference work covers the general pharmacology and neuropharmacology of alcohol as well as the pharmacological mechanisms underlying alcoholism.

The Science of Addiction: From Neurobiology to Treatment

The Science of Addiction: From Neurobiology to Treatment
A Book

by Carlton K. Erickson

  • Publisher : W. W. Norton & Company
  • Release : 2007-02-17
  • Pages : 312
  • ISBN : 9780393076226
  • Language : En, Es, Fr & De
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Runner-up winner of the Hamilton Book Author Award, this book is a comprehensive overview of the neurobiology behind addictions. Neuroscience is clarifying the causes of compulsive alcohol and drug use––while also shedding light on what addiction is, what it is not, and how it can best be treated––in exciting and innovative ways. Current neurobiological research complements and enhances the approaches to addiction traditionally taken in social work and psychology. However, this important research is generally not presented in a forthright, jargon-free way that clearly illustrates its relevance to addiction professionals. The Science of Addiction presents a comprehensive overview of the roles that brain function and genetics play in addiction. It explains in an easy-to-understand way changes in the terminology and characterization of addiction that are emerging based upon new neurobiological research. The author goes on to describe the neuroanatomy and function of brain reward sites, and the genetics of alcohol and other drug dependence. Chapters on the basic pharmacology of stimulants and depressants, alcohol, and other drugs illustrate the specific and unique ways in which the brain and the central nervous system interact with, and are affected by, each of these substances Erickson discusses current and emerging treatments for chemical dependence, and how neuroscience helps us understand the way they work. The intent is to encourage an understanding of the body-mind connection. The busy clinical practitioner will find the chapter on how to read and interpret new research findings on the neurobiological basis of addiction useful and illuminating. This book will help the almost 21.6 million Americans, and millions more worldwide, who abuse or are dependent on drugs by teaching their caregivers (or them) about the latest addiction science research. It is also intended to help addiction professionals understand the foundations and applications of neuroscience, so that they will be able to better empathize with their patients and apply the science to principles of treatment.

The Neurobiology of Drug and Alcohol Addiction

The Neurobiology of Drug and Alcohol Addiction
A Book

by Peter W. Kalivas,Herman H. Samson

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 545
  • ISBN : 9780897667111
  • Language : En, Es, Fr & De
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This text presents the proceedings of a New York Academy of Sciences conference, held in July 1991. Latest advances in chronic drug and alcohol use at molecular, cellular, systems and cognitive levels are comprehensively described including the state of knowledge, directions for future research and clinical applications.

Neurobiological Correlates of Brain Stimulation Reward and Ethanol Withdrawal in the Rat

Neurobiological Correlates of Brain Stimulation Reward and Ethanol Withdrawal in the Rat
A Book

by Darrel John Macey

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 264
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Critical Reviews in Neurobiology

Critical Reviews in Neurobiology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2000
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Drug Addiction

Drug Addiction
A Book

by Jasbir M. Singh,Lyle H. Miller,Harbans Lal

  • Publisher : Unknown Publisher
  • Release : 1972
  • Pages : 329
  • ISBN : 9780883720240
  • Language : En, Es, Fr & De
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Neurobiology of Aging

Neurobiology of Aging
An Interdisciplinary Life-Span Approach

by J. Ordy

  • Publisher : Springer
  • Release : 1975-09-01
  • Pages : 603
  • ISBN : 9780306379161
  • Language : En, Es, Fr & De
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Aging is one of the most universal and inevitable social and sci entific challenges confronting man. The lives of all multicellular organisms begin with conception, extend through phases of development, maturity, senescence and finally end in death. Man is no exception, but has the unique feature of a complex brain. It plays an integra tive role in adaptation to the physical and social environments through reflexes, conditioning and more complex forms of learning. The brain is a repository for both inherited and acquired information. With the development of speech and the formation of symbolic language, the human brain has made it possible to transmit information cultur ally (horizontal) to other members of society, in addition to genetic (vertical) transmission to progeny. This horizontal transmission, which has reached its highest form in man, is a powerful extension of genetic transmission. The brain may provide man all that is of im portance in life. It has played a key role in the evolution of life by maintaining and extending the life span. Many mental or intellectual capacities of man reach a peak in early adulthood, remain relatively constant throughout maturity and then appear to decline during senescence. Behaviorally, there appears to be a decrease in sensory, learning and motor functions with aging in all mammalian species. As integrated adaptive control systems, the brain and neuroendocrines have been closely associated with the homeostatic adaptation to environmental challenges throughout .the life span.

Neurobiology of Mental Illness

Neurobiology of Mental Illness
A Book

by Dennis S. Charney,Eric J. Nestler,Benjamin S. Bunney

  • Publisher : Oxford University Press, USA
  • Release : 2001
  • Pages : 958
  • ISBN : 9780195147803
  • Language : En, Es, Fr & De
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Advances in molecular and cellular biology and in the basic neurosciences are now bringing the revolution in molecular medicine to the field of psychiatry. This is the first comprehensive text to chart that progress. In 70 concise chapters it describes the current state of knowledge aboutthe neurobiological mechanisms underlying psychiatric disorders and shows how this information has the potential to dramatically improve treatment and ultimately lead to prevention. The text has been written by world-renowned experts in basic neuroscience and the pathophysiology and treatment ofpsychiatric disorders. It begins with a concise overview of the basic neurosciences followed by an evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistenetly organized sections on affective disorders, anxiety disorders,psychotic disorders, substance abuse disorders, psychiatric disorders in children, and miscellaneous diagnostic entities. Chatpers are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics. The book iswell-illustrated and contains selected references that willprove valuable to readers. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a unique and valuable resource for students of medicine, neuroscience and psychology; psychiatric residents and other trainees inthe mental health professions; practicing psychiatrists and psychologists; and other healthcare professionals.

Neurobiology of Brain Tumors

Neurobiology of Brain Tumors
A Book

by Michael Salcman

  • Publisher : Unknown Publisher
  • Release : 1991
  • Pages : 386
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Epidemiology & classification/oncogenesis & growth/therapeu- tic rationale & modes of trmt/cell biology of brain tumors.

Hijacking the Brain

Hijacking the Brain
How Drug and Alcohol Addiction Hijacks Our Brains the Science Behind Twelve-Step Recovery

by Louis Teresi

  • Publisher : AuthorHouse
  • Release : 2011-10
  • Pages : 308
  • ISBN : 1463444834
  • Language : En, Es, Fr & De
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Hijacking the Brain provides the first-ever scientific explanation for the success of Twelve-Step programs. Hijacking the Brain examines data provided by recent rapid growth in the fields of neuroscience, neuroimaging, psychology, sociobiology and interpersonal neurobiology that have given us new, dramatic insights into the neural and hormonal correlates of stress and addiction, cognitive decline with addiction, as well as for the relative success of Twelve-Step Programs of recovery. Addiction is recognized by experts as an organic brain disease, and most experts promote Twelve-Step programs (AA, NA, CA, etc.) which invoke a 'spiritual solution' for recovery. To date, no one has described why these programs work. 'Hijack' tells us why. In 'Hijack, ' the role of 'working The Steps' for reducing stress and becoming emotionally centered is discussed in depth. A full chapter is devoted to the rewarding and comforting physiology of meditation and the spiritual experience. The author uses examples from animal sociobiology, as well as sophisticated human brain-imaging studies, to demonstrate that empathic socialization and altruism are instinctive and 'naturally rewarding' and, along with Step Work, act as a substitute for the 'synthetic rewards' of drugs of abuse. 'Hijack' does not challenge the Steps or the Traditions of Twelve-Step programs. The sole intention of Hijacking the Brain is to 'connect the dots' between an 'organic brain disease' and a 'spiritual solution' with sound physical, scientific evidence. Avoiding strict scientific language as much as possible, 'Hijack' is written for the layperson and abundantly illustrated.