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Neurodevelopmental Disorders

Neurodevelopmental Disorders
Comprehensive Developmental Neuroscience

by Bin Chen,Kenneth Y. Kwan

  • Publisher : Academic Press
  • Release : 2020-05-24
  • Pages : 426
  • ISBN : 0128144106
  • Language : En, Es, Fr & De
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Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development

Neurodevelopmental Disorders

Neurodevelopmental Disorders
Employing iPSC Technologies to Define and Treat Childhood Brain Diseases

by Emanuel DiCicco-Bloom,James H. Millonig

  • Publisher : Springer Nature
  • Release : 2020-06-24
  • Pages : 305
  • ISBN : 3030454932
  • Language : En, Es, Fr & De
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This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.

Neurodevelopmental Disorders: A Definitive Guide for Educators

Neurodevelopmental Disorders: A Definitive Guide for Educators
A Book

by Frank E. Vargo

  • Publisher : W. W. Norton & Company
  • Release : 2015-04-20
  • Pages : 384
  • ISBN : 0393709442
  • Language : En, Es, Fr & De
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From autism to ADHD to learning disabilities, a guide for all teachers to this constellation of disorders. Developmental deficits in learning and communication in young children are defined as neurodevelopmental disorders. This constellation, newly defined in the DSM-5, represents a range of issues that educators must address. Neurodevelopmental Disorders: A Definitive Guide for Educators provides extensive and practical information to a range of professionals, and to all others who are interested in the complex and often misunderstood disabilities that fall within the general medical and psychological diagnostic categories of neurodevelopmental disability. Noted psychologist and educator Dr. Frank E. Vargo provides a comprehensive overview of neurodevelopmental deficits and disabilities, as well as of their related learning and cognitive processes, with a strong focus on educational considerations, applications, and relevance across academic areas and with a mind to global educational models. Well researched and accessibly written, this book is an up-to-date and authoritative reference to all of the educational and clinical topics in the diagnostic categories of neurodevelopmental disorder. This informative book will provide a primary reference source for all educators, school and clinical psychologists, clinical mental health counselors and therapists, special education and medical professionals, and parents of children with special needs.

Neurodevelopmental Disorders

Neurodevelopmental Disorders
A Book

by Helen Tager-Flusberg

  • Publisher : MIT Press
  • Release : 1999
  • Pages : 614
  • ISBN : 9780262201162
  • Language : En, Es, Fr & De
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Content Description #"A Bradford Book."#Includes bibliographical references and index.

Neurodevelopmental Disorders in Children and Adolescents

Neurodevelopmental Disorders in Children and Adolescents
A Guide to Evaluation and Treatment

by Christopher J. Nicholls

  • Publisher : Routledge
  • Release : 2018-03-20
  • Pages : 210
  • ISBN : 1315408643
  • Language : En, Es, Fr & De
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Neurodevelopmental Disorders in Children and Adolescents provides an innovative perspective on developmental disorders in youth, one focused on embracing and working with the "messiness" and many variables at play in child and adolescent development. The volume’s approach is aligned with the NIMH Research Domain Criteria project, which hopes to move away from categorical diagnosis toward multidimensional analysis. Each chapter focuses on a particular aspect of development, cluster of diagnoses, or clinical concern. The book also emphasizes humility, an awareness of diversity and difference without stigma, and support for collaborative and integrative healthcare. This is an essential volume for practitioners hoping to improve how they evaluate and treat developmental disorders in children.

Neurodevelopmental Disorders

Neurodevelopmental Disorders
A Book

by W. Wolfgang Fleischhacker,David J. Brooks

  • Publisher : Springer Science & Business Media
  • Release : 2006-05-31
  • Pages : 141
  • ISBN : 3211312226
  • Language : En, Es, Fr & De
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We have great pleasure to present the latest extension of the European Institute of Health Care book series. This volume is devoted to neurodevelopmental d- orders. Again, we had the privilege to be able to work with reknowned experts who have agreed to contribute to this endeavour. The book comprises a number of topics related to psychosocial and motor development and is exemplary with regard to its comprehensiveness, as reviews of the topics presented are generally not available in a single publication. It starts with a timely and critical discussion of the genetics of attention deficit hyperactivity disorder by Dr. Buitelaar in which prospects and challenges of this approach are outlined. The next chapter by Drs. Nicolson and Fawcett deals with dyslexia and its relationship to cerebellar function providing a framework that can explain motor, speed, and phonological deficits in a unified approach. Diagnostic and treatment aspects of speech development disorders are the focus of Dr. Zorowka’s contribution in which, among other issues, the necessity of mul- professional cooperation is stressed. Dr. Sigmundsson then focuses on disorders of motor development. 6-10 % of children have motor competence well below the norm, which often persist. The clumsy child syndrome must be seen and treated as a neurological dysfunction. The relationship between tic disorders and obsessive compulsive disorder, two disturbances generally treated by different medical specialists, namely neurologists or psychiatrists, is then reviewed by Drs.

Neurodevelopmental Disorders

Neurodevelopmental Disorders
Research challenges and solutions

by Jo Van Herwegen,Deborah Riby

  • Publisher : Psychology Press
  • Release : 2014-12-05
  • Pages : 298
  • ISBN : 1317563603
  • Language : En, Es, Fr & De
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Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.

The Genetics of Neurodevelopmental Disorders

The Genetics of Neurodevelopmental Disorders
A Book

by Kevin J. Mitchell

  • Publisher : John Wiley & Sons
  • Release : 2015-09-28
  • Pages : 368
  • ISBN : 1118524888
  • Language : En, Es, Fr & De
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Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Neurodevelopmental Disorders

Neurodevelopmental Disorders
Research challenges and solutions

by Jo Van Herwegen,Deborah Riby

  • Publisher : Psychology Press
  • Release : 2014-12-05
  • Pages : 298
  • ISBN : 1317563603
  • Language : En, Es, Fr & De
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Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.

Neurodevelopmental Disorders

Neurodevelopmental Disorders
Diagnosis and Treatment

by Randi Jenssen Hagerman

  • Publisher : Oxford University Press
  • Release : 1999-09-16
  • Pages : 224
  • ISBN : 0198028695
  • Language : En, Es, Fr & De
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Neurodevelopmental Disorders: Diagnosis and Treatment summarizes a vast body of literature concerning diagnosis and treatment for a variety of neurodevelopmental disorders, including both common and rare conditions. Throughout the book, Dr. Hagerman synthesizes treatment information for many disciplines that work together to provide multi-modality intervention. Psychopharmacological information and recommendations as well as the latest knowledge regarding genetic and diagnostic aspects of each disorder are explained in detail. And all chapters have one or more case studies to model the treatment recommendations, which are enhanced by extensive appendices reviewing educational programs, computer software, and supplementary reading. In addition, a detailed resource list of organizations, educational materials, and internet connections accompanies each chapter. This book not only integrates but also advances our knowledge of treatment, which is of prime importance for clinicians, therapists, educators, and parents.

The Genetics of Neurodevelopmental Disorders

The Genetics of Neurodevelopmental Disorders
A Book

by Kevin J. Mitchell

  • Publisher : John Wiley & Sons
  • Release : 2015-08-04
  • Pages : 368
  • ISBN : 1118524977
  • Language : En, Es, Fr & De
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Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Treatment of Neurodevelopmental Disorders

Treatment of Neurodevelopmental Disorders
Targeting Neurobiological Mechanisms

by Randi Hagerman,Robert Hendren

  • Publisher : Oxford University Press
  • Release : 2014-04-25
  • Pages : 352
  • ISBN : 0199378886
  • Language : En, Es, Fr & De
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This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.

Neurodevelopmental Disorders: A Definitive Guide for Educators

Neurodevelopmental Disorders: A Definitive Guide for Educators
A Book

by Frank E. Vargo

  • Publisher : W. W. Norton & Company
  • Release : 2015-04-20
  • Pages : 384
  • ISBN : 0393709442
  • Language : En, Es, Fr & De
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From autism to ADHD to learning disabilities, a guide for all teachers to this constellation of disorders. Developmental deficits in learning and communication in young children are defined as neurodevelopmental disorders. This constellation, newly defined in the DSM-5, represents a range of issues that educators must address. Neurodevelopmental Disorders: A Definitive Guide for Educators provides extensive and practical information to a range of professionals, and to all others who are interested in the complex and often misunderstood disabilities that fall within the general medical and psychological diagnostic categories of neurodevelopmental disability. Noted psychologist and educator Dr. Frank E. Vargo provides a comprehensive overview of neurodevelopmental deficits and disabilities, as well as of their related learning and cognitive processes, with a strong focus on educational considerations, applications, and relevance across academic areas and with a mind to global educational models. Well researched and accessibly written, this book is an up-to-date and authoritative reference to all of the educational and clinical topics in the diagnostic categories of neurodevelopmental disorder. This informative book will provide a primary reference source for all educators, school and clinical psychologists, clinical mental health counselors and therapists, special education and medical professionals, and parents of children with special needs.

Neurodevelopmental Disorders Across the Lifespan

Neurodevelopmental Disorders Across the Lifespan
A Neuroconstructivist Approach

by Emily K. Farran,Annette Karmiloff-Smith

  • Publisher : Oxford University Press
  • Release : 2012
  • Pages : 394
  • ISBN : 0199594813
  • Language : En, Es, Fr & De
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Williams syndrome is a rare neurodevelopmental disorder caused by a genetic abnormality. It has played an important role in helping us understand the nature and course of cognitive development, and in particular, the relationship between genes, the brain, and the environment during development (providing evidence for the idea that the interaction between all three is important). For this reason, the editors of Neurodevelopmental Disorders Across theLifespan use this syndrome as a model disorder to consider cognitive development. The book brings together leading scientists from the fields of psychology, neuroscience, and genetics to present the latest evidenceon development across the lifespan across multiple levels of description (genetic, brain, cognitive, environmental) within a cognitive neuroscience perspective.

Neurodevelopmental Disorders: Cognitive Behavioural Phenotypes

Neurodevelopmental Disorders: Cognitive Behavioural Phenotypes

by Daria Riva,U. Bellugi,M.B. Denckla

  • Publisher : John Libbey Eurotext
  • Release : 2005-06-01
  • Pages : 329
  • ISBN : 2742013415
  • Language : En, Es, Fr & De
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In recent years our approach to neurodevelopmental disorders has undergone extraordinary change. This has resulted from tremendous progress in various different disciplines including developmental neuroscience, behavioural and molecular genetics, and developmental neurobiology, and from the very high quality now achievable in neuroimaging and neurophysiological techniques. This publication aims to provide a concise and interdisciplinary approach to the study of the different cognitive/behavioural phenotypes encountered in a wide range of neurodevelopmental disorders. Starting from methodological, nosographic, and assessment premises, the book deals with selected disorders of a defined but still complex genetic aetiology, and concludes with a description of the neuropsychiatric disorders that are most commonly encountered during development.

New mechanisms and therapeutics in neurodevelopmental disorders

New mechanisms and therapeutics in neurodevelopmental disorders
A Book

by Daniela Tropea

  • Publisher : Frontiers E-books
  • Release : 2021
  • Pages : 329
  • ISBN : 2889190676
  • Language : En, Es, Fr & De
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Neurodevelopmental disorders (NDDs) are severe, heritable conditions characterized by impaired brain development and disability in cognition, social interaction and behavior. Genetic predisposition appears to interact with environmental factors to produce the onset of the disease. In the last decade genomic analysis on NDDs advanced the knowledge of the genetic causes of these disorders: most of the genes identified were not predicted from known biology, and almost all of them engage in neurodevelopmental processes. However, the same studies revealed an unexpected outcome regarding the molecular etiology: many of the same susceptibility genes as well as molecular pathways are emerging across hitherto unrelated disorders- such as autism and schizophrenia- challenging how we conceptualize these conditions. These new discoveries call for the establishment of additional criteria for the classification of the genes and related phenotypes. Beyond the classical distinction according to diagnostic criteria, new parameters should be taken into account: the genetics, the neurobiology of the gene products and the molecular mechanisms that they control. Our broad understanding of NDDs, requires a combination of approaches, including human studies, animal models and theoretical computation. Indeed, progress in technology and the generation of accurate models are advancing the field, and the research is rapidly growing. This Research Topic presents recent advances in neurodevelopmental disorders from genes to systems, in single conditions and across different phenotypes, and report the newest treatments in use. Recognized experts in the field discuss recent findings in molecular studies, in vivo imaging, neuropsychology, neuropharmacology and computational neuroscience. This multidisciplinary approach enriches our understanding of the mechanisms involved in the onset and progression of NDDs with the perspective of revealing the biological signs of the disorders and identifying new therapeutics.

Autism and Other Neurodevelopmental Disorders

Autism and Other Neurodevelopmental Disorders
A Book

by Robin L. Hansen,Sally J. Rogers

  • Publisher : American Psychiatric Pub
  • Release : 2013
  • Pages : 306
  • ISBN : 158562425X
  • Language : En, Es, Fr & De
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Autism and Other Neurodevelopmental Disorders gathers and organizes the most recent information in this important and rapidly expanding field into a clinically useful volume that will enable clinicians, patients, and families to understand these disorders and make sound treatment decisions in light of recent research. The editors, as well as most of the chapter authors, are faculty or former trainees at the prestigious Medical Investigation of Neurodevelopmental Disorders (MIND) Institute at UC-Davis, a collaborative international research center committed to the awareness, understanding, prevention, care, and cure of neurodevelopmental disorders, including autism spectrum disorders, ADHD, learning disorders, and more. Each chapter presents signs and symptoms; epidemiology and etiology; diagnostic approaches; evidence based interventions; and reviews of promising research. By focusing on the range of neurodevelopmental disorders commonly seen and managed by both primary and subspecialist health care professionals. Autism and Other Neurodevelopmental Disorders explains cutting-edge research and advances in clinical care, and assembles them into a single, indispensable volume.

Working Memory and Neurodevelopmental Disorders

Working Memory and Neurodevelopmental Disorders
A Book

by Tracy Packiam Alloway,Susan E. Gathercole

  • Publisher : Psychology Press
  • Release : 2012-08-06
  • Pages : 320
  • ISBN : 1135421358
  • Language : En, Es, Fr & De
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Short-term or working memory - the capacity to hold and manipulate information mentally over brief periods of time - plays an important role in supporting a wide range of everyday activities, particularly in childhood. Children with weak working memory skills often struggle in key areas of learning and, given its impact on cognitive abilities, the identification of working memory impairments is a priority for those who work with children with learning disabilities. Working Memory and Neurodevelopmental Disorders supports clinical assessment and management of working memory deficits by summarising the current theoretical understanding and methods of assessment of working memory. It outlines the working memory profiles of individuals with a range of neurodevelopmental disorders (including Down's syndrome, Williams syndrome, Specific Language Impairment, and ADHD), and identifies useful means of alleviating the anticipated learning difficulties of children with deficits of working memory. This comprehensive and informative text will appeal to academics and researchers in cognitive psychology, neuropsychology and developmental psychology, and will be useful reading for students in these areas. Educational psychologists will also find this a useful text, as it covers the role of working memory in learning difficulties specific to the classroom.

Animal Models of Neurodevelopmental Disorders

Animal Models of Neurodevelopmental Disorders
A Book

by Jerome Y. Yager

  • Publisher : Humana Press
  • Release : 2015-09-20
  • Pages : 267
  • ISBN : 9781493927081
  • Language : En, Es, Fr & De
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Providing a spectrum of models that is reflective of the various species that can be utilized in experimentation on disorders across a broad range of developmental disabilities, this volume collects expert contributions involved in investigation of the causes, outcomes, treatment, and prevention. Animal Models of Neurodevelopmental Disorders explores models of perinatal hypoxia-ischemia/cerebral palsy and stroke, autism spectrum disorder, fetal alcohol syndrome, as well as mental retardation. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Practical and authoritative, Animal Models of Neurodevelopmental Disorders serves to introduce and entice those interested in better understanding and treating these disorders to the vital animal model world of investigation.

Sleep and its Disorders in Children and Adolescents with a Neurodevelopmental Disorder

Sleep and its Disorders in Children and Adolescents with a Neurodevelopmental Disorder
A Book

by Gregory Stores

  • Publisher : Cambridge University Press
  • Release : 2014-10-27
  • Pages : 176
  • ISBN : 1107402204
  • Language : En, Es, Fr & De
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"The first English textbook of paediatrics, The Boke of Chyldren, was published in the mid-16th century. The author was Thomas Phaire, a lawyer and physician, who wished to draw attention (in fanciful terms by modern standards) to the clinical features, supposed causes, and recommended treatments of various "infirmities of children": "Although (as affirmeth Plinie) there are innumerable passions & diseases, where unto the bodye of man is subiecte, and as well maye chaunce in the young as in the olde: Yetfor moste commonly the tender age of children is chefely vexed and greuved with these diseases folowyng" (Phaire, 1545INT-017)"--Provided by publisher.