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Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

Neuroprotection in Autism, Schizophrenia and Alzheimer's disease
A Book

by Illana Gozes,Joseph Levine

  • Publisher : Academic Press
  • Release : 2019-10-16
  • Pages : 322
  • ISBN : 0128140380
  • Language : En, Es, Fr & De
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Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders. Offers an up-to-date overview of basic and clinical studies concerning similarities in the most prevalent brain disorders Helps the reader become familiar with novel neuroprotective mechanisms and experimental treatment modalities in these difficult to treat disorders Written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry

Neuroprotection in Alzheimer's Disease

Neuroprotection in Alzheimer's Disease
A Book

by Illana Gozes

  • Publisher : Academic Press
  • Release : 2016-12-30
  • Pages : 342
  • ISBN : 0128037121
  • Language : En, Es, Fr & De
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Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Estrogens and Memory

Estrogens and Memory
Basic Research and Clinical Implications

by Karyn M. Frick

  • Publisher : Oxford University Press, USA
  • Release : 2020
  • Pages : 516
  • ISBN : 0190645903
  • Language : En, Es, Fr & De
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"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estradiol plus testosterone prevented this decline (Sherwin, 1988). As a search for the terms "estrogen" and "memory" in PubMed illustrates, well over 2000 papers have been published on the subject of estrogens and memory in the ensuing decades. The vast majority of these studies have focused on the hippocampus, a bilateral medial temporal lobe structure essential for the formation of episodic memories, particularly those with spatial, contextual, relational, temporal, and recognition components (Olton et al., 1979; Morris et al., 1982; Kim and Fanselow, 1992; Squire, 1992; Cohen and Stackman, 2015; Tonegawa et al., 2015; Eichenbaum, 2017). Although various forms of learning and memory are mediated by numerous brain regions, including the prefrontal cortex, medial temporal lobe cortices, amygdala, striatum, and cerebellum, the hippocampus has received the lion's share of attention due to its central importance for episodic memory formation. Hippocampal damage produces profound retrograde amnesia for facts and events, as well as anterograde amnesia for new information and impairments in spatial navigation (Winocur, 1990; Anagnostaras et al., 2001; Clark et al., 2002; Gilboa et al., 2006). Hippocampal dysfunction in middle-aged and aged subjects is a primary contributor to age-related memory decline (Golumb et al., 1996; Grady et al., 2003; Apostolova et al., 2010; Burke and Barnes, 2010; Small et al., 2011; Yassa et al., 2011), and has also been implicated in the cognitive impairments observed in diseases such as schizophrenia and depression (Small et al., 2011; Nakahara et al., 2018; Santos et al., 2018; Ott et al., 2019). Moreover, the hippocampi of patients with Alzheimer's disease are substantially atrophied and burdened with copious amounts of amyloid plaques and neurofibrillary tangles, the hallmark pathologies of this insidious disease (Hyman et al., 1984; Walsh and Selkoe, 2004; Selkoe and Hardy, 2016). As such, understanding how estrogens influence hippocampal functioning may provide important insights not only about the fundamental neurobiology of memory processes, but also into the etiology of neuropsychiatric and neurodegenerative diseases"--

Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Receptors in the Evolution and Development of the Brain

Receptors in the Evolution and Development of the Brain
Matter into Mind

by Richard E. Fine, MD

  • Publisher : Academic Press
  • Release : 2019-04-15
  • Pages : 300
  • ISBN : 0128110120
  • Language : En, Es, Fr & De
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Receptors in the Evolution and Development of the Brain: Matter into Mind presents the key role of receptors and their cognate ligands in wiring the mammalian brain from an evolutionary developmental biology perspective. It examines receptor function in the evolution and development of the nervous system in the large vertebrate brain, and discusses rapid eye movement sleep and apoptosis as mechanisms to destroy miswired neurons. Possible links between trophic deficits and connectional diseases including Alzheimer's, Parkinson's, and ALS are also discussed. This book is extremely useful to those with an interest in the molecular and cellular neurosciences, including those in cognitive and clinical branches of this subject, and anyone interested in how the incredibly complex human brain can build itself. Provides an understanding of the key role receptors play in brain development and the selection process necessary to construct a large brain Traces the evolution of receptors from the most primitive organisms to humans Emphasizes the roles that REM sleep and apoptosis play in this selection via trophic factors and receptors Describes the role that trophic factor-receptor interactions play throughout life and how trophic deficits can lead to connectional diseases, including Alzheimer's, Parkinson's and ALS Provides a potential mechanism whereby neuronal stem cells can cure these diseases

Human Hypothalamus: Basic and Clinical Aspects, Part I

Human Hypothalamus: Basic and Clinical Aspects, Part I
A Book

by Dick F. Swaab

  • Publisher : Elsevier
  • Release : 2003-12-29
  • Pages : 508
  • ISBN : 9780444513571
  • Language : En, Es, Fr & De
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As the human hypothalamus has traditionally been considered part of the neuroendocrine system, it has been of little interest to neurologists. This volume creates renewed interest in the subject, highlighting groundbreaking research that links this complex part of the human brain to a variety of neurological and psychological disorders. Clinicians, researchers, and practitioners from a variety of medical fields will find this to be a comprehensive presentation of new research that applies to a variety of disorders, including their origin, diagnosis, and treatment. From groundbreaking discussions that link the human hypothalamus to attention deficits in the dementias, to its role in disorders such as narcolepsy and certain epilepsies, users will find this volume to be an invaluable resource for research and patient care. Specific information on topics including depression, eating disorders, aggression, and mental retardation are included, giving those in the field of neurology, psychiatry, endocrinology, and pediatrics a comprehensive understanding on how the human hypothalamus is related to patient disorders in these fields. * A comprehensive accounting of groundbreaking new research regarding the human hypothalamus * New insights on the hypothalamus and its role in disorders, including dementias, epilepsies, and associated psychiatric diseases * A greater understanding of how the human hypothalamus impacts research and treatment protocols in a variety of fields, including neurology, endocrinology, and psychology

CSA Neurosciences Abstracts

CSA Neurosciences Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Biology Annual Report

Biology Annual Report
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Imaging of the Nervous System

Imaging of the Nervous System
Diagnostic and Therapeutic Applications

by Richard E. Latchaw,John Kucharczyk,Michael Eugene Moseley

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 1776
  • ISBN : 9789997629890
  • Language : En, Es, Fr & De
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A comprehensive account of the latest imaging techniques for both diagnosis and image-guided therapy for the many diseases of the nervous system. The book provides summary boxes and tables covering the classification of pathology, key features of the disorder, and differential diagnosis, as well as, essential color images. An accompanying CD-ROM features additional illustrations, descriptions for a particular diagnosis or therapy, and video clips of specific procedures.

Dogs & Human Health

Dogs & Human Health
The New Science of Dog Therapy & Therapy Dogs

by Milena Penkowa

  • Publisher : Balboa Press
  • Release : 2015-06-08
  • Pages : 318
  • ISBN : 1452529035
  • Language : En, Es, Fr & De
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What if you could significantly improve your physical and mental health by taking a simple step thats easy, rewarding, and fun? Dr. Milena Penkowa says you can do that and more by owning a dog and yet people continue to invest time and money in costly treatments before even considering a furry friend. Dogs can stave off diseases and certain cancers, erase pain, and ease anxiety, depression, allergies, diabetes, and cardiovascular disorders. Over the long term, they can also reduce the burden of dementia, epilepsy, stroke, Parkinsons disease, schizophrenia and autism. This guidebook explains the scientifically proven benefits of dogs, and youll learn how dogs: change the human brain so it reacts and thinks differently; improve the immune system to make you more resilient than dog deprived individuals; boost and invigorate the human spirit and secure happiness; promote a life of longevity and healthiness. Stop looking for fancy remedies to physical and mental problems, and start looking for a dog wagging its tail. Tap into a natural method to survive and thrive by learning about the fascinating connections between Dogs & Human Health.

Goldfrank's Toxicologic Emergencies, Eleventh Edition

Goldfrank's Toxicologic Emergencies, Eleventh Edition
A Book

by Lewis S. Nelson,Robert S. Hoffman,Mary Ann Howland,Neal A. Lewin,Lewis R. Goldfrank

  • Publisher : McGraw Hill Professional
  • Release : 2018-08-22
  • Pages : 329
  • ISBN : 1259859592
  • Language : En, Es, Fr & De
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Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Goldfrank’s is the premier toxicology textbook that should be in every emergency department or poison center library. Whether you are a student, resident, or faculty, there is something here for you. If you are a toxicology fellow or poison specialist studying for your boards, this is your go-to book. I highly recommend this work... —The Journal of Emergency Medicine The best edition yet of the landmark text in medical toxicology A Doody’s Core Title for 2020! Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins. Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations. The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis. New to this Edition: • Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes • New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies • New content on toxicogenomics explores its increasingly important role in predictive toxicology • Chapter-ending bulleted summaries of key points • Updated coverage of synthetics such as “K2” • Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools

Biology Digest

Biology Digest
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Dissertation Abstracts International

Dissertation Abstracts International
The sciences and engineering. B

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Psychiatric Drugs Explained

Psychiatric Drugs Explained
A Book

by David Healy

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 345
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This book provides a comprehensive and clear guide to the uses, benefits and impact of psychotropic drugs. It conveys the lived experience of the problems that can be caused by side-effects and the nature of the trade-off that patients may need to make between the benefits brought about with the drugs and the problems they cause.

Goldfrank's Toxicologic Emergencies, Tenth Edition (ebook)

Goldfrank's Toxicologic Emergencies, Tenth Edition (ebook)
A Book

by Robert Hoffman,Mary Ann Howland,Neal Lewin,Lewis Nelson,Lewis Goldfrank

  • Publisher : McGraw Hill Professional
  • Release : 2014-09-22
  • Pages : 1904
  • ISBN : 0071801855
  • Language : En, Es, Fr & De
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The standard-setting reference in medical toxicology—trusted as the leading evidencebased resource for poison emergencies A Doody's Core Title for 2017! For decades, one name has been synonymous with the most respected, rigorous perspectives on medical toxicology and the treatment of poisoned and overdosed patients: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank’s delivers essential, patientcenteredcoverage of every aspect of poison management. The editors and authors are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to cutting-edge treatment strategies. Goldfrank's Toxicologic Emergencies, Tenth Edition begins with an examination of medical toxicology principles and techniques. It then reviews the biochemical, molecular, and pathophysiologic basis of toxicology, followed by an intense focus on toxicologic principles related to special patient populations. Features Case studies enhance your understanding of the clinical application of the text material Practical focus on the pathophysiologic basis of medical toxicology The Antidotes in Depth sections delivers the expertise of toxicologists across the world as they present treatments for critically ill poisoned and overdosed patients and allow you to easily identify key issues relating to the use of complex and often unfamiliar therapies The principles of risk management, medicolegal decision making, patient safety, post mortem toxicology and the assessment of ethanol induced impairment described in chapters and Special Considerations emphasize the interface between medical toxicology, the law, and quality care

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders
Biological Basis of Neurological and Psychiatric Disorders

by Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland

  • Publisher : Elsevier
  • Release : 2014-12-03
  • Pages : 824
  • ISBN : 0123982804
  • Language : En, Es, Fr & De
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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Clinical Evidence Concise

Clinical Evidence Concise
The International Resource of the Best Available Evidence for Effective Health Care

by William McGuire

  • Publisher : Bmj Publishing Group
  • Release : 2005
  • Pages : 652
  • ISBN : 9781905545001
  • Language : En, Es, Fr & De
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A source of the available evidence for effective health care.

Proceedings

Proceedings
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1991
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Chemical Abstracts

Chemical Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Brain Disabling Treatments in Psychiatry

Brain Disabling Treatments in Psychiatry
Drugs, Electroshock, and the Psychopharmaceutical Complex

by Peter R. Breggin

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 546
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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