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New Techniques for Management of ‘Inoperable’ Gliomas

New Techniques for Management of ‘Inoperable’ Gliomas
A Book

by Michael E. Sughrue,Isaac Yang

  • Publisher : Academic Press
  • Release : 2019-08-03
  • Pages : 256
  • ISBN : 0128136340
  • Language : En, Es, Fr & De
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New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

The Glioma Book

The Glioma Book
A Book

by Michael E. Sughrue

  • Publisher : Thieme
  • Release : 2019-10-25
  • Pages : 350
  • ISBN : 1626234450
  • Language : En, Es, Fr & De
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A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.

Glioma

Glioma
Contemporary Diagnostic and Therapeutic Approaches

by Ibrahim Omerhodzic,Kenan Arnautovic

  • Publisher : BoD – Books on Demand
  • Release : 2019-01-16
  • Pages : 258
  • ISBN : 1789849535
  • Language : En, Es, Fr & De
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The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors
A Book

by Kaisorn Chaichana,Alfredo Quinones-Hinojosa

  • Publisher : Academic Press
  • Release : 2019-02-28
  • Pages : 506
  • ISBN : 0128117842
  • Language : En, Es, Fr & De
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Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them. Provides a comprehensive review of different approaches, explaining them step-by- step Includes diagrams that show surgical approaches Presents the advantages and disadvantages of each approach to aid in decision-making

Diffuse Low-Grade Gliomas in Adults

Diffuse Low-Grade Gliomas in Adults
Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies

by Hugues Duffau

  • Publisher : Springer Science & Business Media
  • Release : 2013-03-19
  • Pages : 502
  • ISBN : 1447122135
  • Language : En, Es, Fr & De
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This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Management of Adult Glioma in Nursing Practice

Management of Adult Glioma in Nursing Practice
A Book

by Ingela Oberg

  • Publisher : Springer
  • Release : 2019-01-04
  • Pages : 314
  • ISBN : 331976747X
  • Language : En, Es, Fr & De
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This contributed book focuses on the nursing care and considerations for the most common type of malignant brain tumours – gliomas, out of the 150 different types of brain tumours . The reader will gain specialist knowledge in understanding the disease trajectory of malignant gliomas and gain a deeper understanding of the presenting symptoms and varying treatment options of this highly malignant tumour. High grade malignant gliomas impact significantly on prognosis, with an average life expectancy of 18-24 months from diagnosis, given maximum treatment options including surgery, chemotherapy and radiotherapy. This book takes you through all current treatment options with their associated risks and intended benefits. Brain tumours affect not just the patient, but their family and carers too and this important aspect of holistic nursing care is not to be overlooked. This book encompasses first hand experiences of both a brain tumour patient living with a glioma and aspects from a carer. The structure of this book follows a typical patient pathway from presenting signs / symptoms through to MDT (multidisciplinary team) discussions to surgical techniques and radiological investigations, right through to chemotherapy, radiotherapy and palliative care including end of life care. It provides a distinct overview of the holistic needs spectrum encompassing the entire patient journey and equips the reader with learning objectives set at every chapter. Although this book is primarily aimed at Nurses working at ward level within neuro-oncology, this book is also intended to benefit professionals new to the field of specialist nursing – in particular those working with adult brain tumours and neuro-oncology.

New Approaches to the Management of Primary and Secondary CNS Tumors

New Approaches to the Management of Primary and Secondary CNS Tumors
A Book

by Lee Roy Morgan

  • Publisher : BoD – Books on Demand
  • Release : 2017-03-23
  • Pages : 214
  • ISBN : 953513051X
  • Language : En, Es, Fr & De
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Several new concepts are reviewed and discussed in this book and allude to the transport of drugs bound to red blood cells into the vascular blood-brain barrier and into cancer cells. Such a transport system is novel and of potential therapeutic potential. It is the goal of this book to provide information and data that will be useful for others to develop new approaches for the management of CNS malignancies.

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy
A Book

by Herbert B. Newton

  • Publisher : Academic Press
  • Release : 2018-03-28
  • Pages : 848
  • ISBN : 0128121017
  • Language : En, Es, Fr & De
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Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Intracranial Gliomas Part II - Adjuvant Therapy

Intracranial Gliomas Part II - Adjuvant Therapy
A Book

by M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2018-01-25
  • Pages : 252
  • ISBN : 3318060593
  • Language : En, Es, Fr & De
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Treatment of patients with intracranial gliomas, especially high-grade neoplasms, usually requires postoperative adjuvant therapy. Significant progress in the understanding of tumor biology, technological advances in irradiation delivery, and development of novel antitumor drugs have led to an expansion of the therapeutic arsenal in neuro-oncology. This publication provides a unique review of the various options for adjuvant therapy. Special emphasis is on current evidence-based treatment standards and guidelines, and on perspectives of further improvement in long-term outcomes. Chapters review the histopathological and molecular features of gliomas and describe basic principles and clinical results of fractionated radiotherapy, stereotactic radiosurgery, brachytherapy, use of radiosensitizers, systemic chemotherapy and antiangiogenic therapy. Particular attention is paid to treatment of pediatric patients and to physical and psychological rehabilitation and supportive care at the end of life. This book and its accompanying volumes are mainly directed at neuro-oncologists, radiation oncologists, and other clinicians treating patients with brain tumors.

Handbook of Clinical Neurology

Handbook of Clinical Neurology
A Book

by P. J. Vinken,G. W. Bruyn

  • Publisher : Unknown Publisher
  • Release : 1974
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cumulated Index Medicus

Cumulated Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Tumours of the Brain and Skull

Tumours of the Brain and Skull
Part III.

by P. J. Vinken,G. W. Bruyn

  • Publisher : Unknown Publisher
  • Release : 1975
  • Pages : 582
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Fast Facts: Brain Tumors

Fast Facts: Brain Tumors
A Book

by Lauren E. Abrey,Warren P. Mason

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2011-01-01
  • Pages : 144
  • ISBN : 1905832877
  • Language : En, Es, Fr & De
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Despite the availability of many effective treatments, there remains a therapeutic nihilism associated with brain tumors. This highly readable second edition of 'Fast Facts: Brain Tumors' challenges this view, starting from the premise that patients with brain tumors can truly benefit from a thoughtful multidisciplinary approach. This comprehensive handbook covers all the salient features of the various brain tumors and treatment modalities in a way that will be useful to the practicing clinician. • Advances in radiology and pathology that have led to more precise and detailed diagnoses • Developments in molecular biology and imaging techniques that have improved available diagnostic modalities • New neurosurgical techniques that have enabled operations on tumors that were previously considered inoperable • Novel delivery systems that allow various treatments to reach tumors that are otherwise protected by the blood-brain barrier. This fully updated edition of 'Fast Facts: Brain Tumors' bridges the gap between primary care providers - whose role is pivotal in tumor detection and subsequent patient care - and first-level specialists such as general neurologists and neurosurgeons. Its key message is that selection of the best initial approach for an individual patient will result in the best overall outcome, both in terms of survival and quality of life. 'Fast Facts: Brain Tumors' is specifically for the primary care physician whose role is pivotal in tumor detection and subsequent patient care. Contents: • Classification and epidemiology • Diagnosis • Treatment • Brain metastases • Gliomas • Meningiomas • Neuronal tumors • Pineal region tumors • Skull base tumors • Primary central nervous system lymphoma • Brain tumor syndromes and tumor-like cysts • Geriatric neuro-oncology • Useful resources

Abstracts and Descriptions of Contributions to the Scientific Program

Abstracts and Descriptions of Contributions to the Scientific Program
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1961
  • Pages : 181
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Brain Tumors

Brain Tumors
An Update

by Amit Agrawal,Luis Rafael Moscote-Salazar

  • Publisher : BoD – Books on Demand
  • Release : 2018-08-22
  • Pages : 248
  • ISBN : 1789235561
  • Language : En, Es, Fr & De
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We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book "Brain Tumor - An Update" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book.

Radiation Injury to the Nervous System

Radiation Injury to the Nervous System
A Book

by Philip H. Gutin,Steven A. Leibel,Glenn E. Sheline

  • Publisher : Lippincott Williams & Wilkins
  • Release : 1991
  • Pages : 482
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The experimental results & clinical experiences of tolerance of nervous system to ionizing radiation/normal tissue/etc.

Handbook of Brain Tumor Chemotherapy

Handbook of Brain Tumor Chemotherapy
A Book

by Herbert B. Newton

  • Publisher : Elsevier
  • Release : 2005-12-19
  • Pages : 586
  • ISBN : 9780080455938
  • Language : En, Es, Fr & De
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Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors

Intracranial Gliomas Part III - Innovative Treatment Modalities

Intracranial Gliomas Part III - Innovative Treatment Modalities
A Book

by M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2018-07-10
  • Pages : 222
  • ISBN : 3318060631
  • Language : En, Es, Fr & De
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At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.

Carbon-Ion Radiotherapy

Carbon-Ion Radiotherapy
Principles, Practices, and Treatment Planning

by Hirohiko Tsujii,Tadashi Kamada,Toshiyuki Shirai,Koji Noda,Hiroshi Tsuji,Kumiko Karasawa

  • Publisher : Springer Science & Business Media
  • Release : 2013-12-25
  • Pages : 312
  • ISBN : 4431544577
  • Language : En, Es, Fr & De
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This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.

Neurooncology

Neurooncology
Newer Developments

by Amit Agrawal

  • Publisher : BoD – Books on Demand
  • Release : 2016-07-13
  • Pages : 488
  • ISBN : 9535124250
  • Language : En, Es, Fr & De
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The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management.