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Oncology Informatics

Oncology Informatics
Using Health Information Technology to Improve Processes and Outcomes in Cancer

by Bradford W. Hesse,David Ahern,Ellen Beckjord

  • Publisher : Academic Press
  • Release : 2016-03-17
  • Pages : 448
  • ISBN : 0128022000
  • Language : En, Es, Fr & De
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Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health." Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice

Oncology Informatics

Oncology Informatics
Using Health Information Technology to Improve Processes and Outcomes in Cancer Care

by Bradford W. Hesse,David Ahern,Ellen Beckjord

  • Publisher : Academic Press
  • Release : 2016-03-01
  • Pages : 400
  • ISBN : 9780128021156
  • Language : En, Es, Fr & De
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Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates NCI-collected evidence into a format that is optimally useful for hospital planners, physicians, researchers, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. It is a translational guide for moving evidence into practice, and meets recommendations from the national Academies of Science to reorient the research portfolio toward providing greater cognitive support for physicians, patients, and their caregivers to improve patient outcomes. Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission that can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of smart and connected health and acts as a formational guide for turning clinical systems into engines of discovery. Following recommendations from the IOM's Roundtable on Evidence-Based Medicine, the authors encapsulate best practice for creating a Learning Healthcare System in oncology. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice

Informatics in Radiation Oncology

Informatics in Radiation Oncology
A Book

by George Starkschall,R. Alfredo C. Siochi

  • Publisher : CRC Press
  • Release : 2013-09-05
  • Pages : 329
  • ISBN : 1439825823
  • Language : En, Es, Fr & De
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Reflecting the increased importance of the collaborations between radiation oncology and informatics professionals, Informatics in Radiation Oncology discusses the benefits of applying informatics principles to the processes within radiotherapy. It explores how treatment and imaging information is represented, stored, and retrieved as well as how this information relates to other patient data. The book deepens your knowledge of current and emerging information technology and informatics principles applied to radiation oncology so that all the data gathered—from laboratory results to medical images—can be fully exploited to make treatments more effective and processes more efficient. After introducing the basics of informatics and its connection to radiation oncology, the book examines the process of healthcare delivery in radiation oncology, the challenges of managing images in radiotherapy, and the burgeoning field of radiogenomics. It then presents teaching, clinical trials, and research tools and describes open access clinical imaging archives in radiotherapy, techniques for maximizing information from multimodality imaging, and the roles of images in treatment planning. It also looks at how informatics can improve treatment planning, the safety and efficiency of delivery systems, image-guided patient positioning, and patient assessment. The book concludes with discussions on how outcomes modeling evaluates the effectiveness of treatments, how quality control informatics improves the reliability of processes, and how to perform quality assurance on the informatics tools. With contributions from a host of top international experts in radiation oncology, medical physics, and informatics, this book leads the way in moving the field forward. It encourages you to find new ways of applying informatics to radiation oncology and help your patients in their fight against cancer.

Consumer Informatics and Digital Health

Consumer Informatics and Digital Health
Solutions for Health and Health Care

by Margo Edmunds,Christopher Hass,Erin Holve

  • Publisher : Springer
  • Release : 2019-01-17
  • Pages : 408
  • ISBN : 3319969064
  • Language : En, Es, Fr & De
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This unique collection synthesizes insights and evidence from innovators in consumer informatics and highlights the technical, behavioral, social, and policy issues driving digital health today and in the foreseeable future. Consumer Informatics and Digital Health presents the fundamentals of mobile health, reviews the evidence for consumer technology as a driver of health behavior change, and examines user experience and real-world technology design challenges and successes. Additionally, it identifies key considerations for successfully engaging consumers in their own care, considers the ethics of using personal health information in research, and outlines implications for health system redesign. The editors’ integrative systems approach heralds a future of technological advances tempered by best practices drawn from today’s critical policy goals of patient engagement, community health promotion, and health equity. Here’s the inside view of consumer health informatics and key digital fields that students and professionals will find inspiring, informative, and thought-provoking. Included among the topics: • Healthcare social media for consumer informatics • Understanding usability, accessibility, and human-centered design principles • Understanding the fundamentals of design for motivation and behavior change • Digital tools for parents: innovations in pediatric urgent care • Behavioral medicine and informatics in the cancer community • Content strategy: writing for health consumers on the web • Open science and the future of data analytics • Digital approaches to engage consumers in value-based purchasing Consumer Informatics and Digital Health takes an expansive view of the fields influencing consumer informatics and offers practical case-based guidance for a broad range of audiences, including students, educators, researchers, journalists, and policymakers interested in biomedical informatics, mobile health, information science, and population health. It has as much to offer readers in clinical fields such as medicine, nursing, and psychology as it does to those engaged in digital pursuits.

Oncology and Informatics

Oncology and Informatics
Special Topic Issue: Oncology 2020, Vol. 98, No. 6

by Paul Martin Putora

  • Publisher : Unknown Publisher
  • Release : 2020-06-26
  • Pages : 124
  • ISBN : 9783318067446
  • Language : En, Es, Fr & De
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Oncology practice and research have been permeated and transformed by informatics - while some changes have been very apparent and welcome, others have occurred in the background without us noticing and, in some cases, we find ourselves depending on informatics without ever having asked for it. The new "Informatics and Oncology" section will provide a forum within the journal to address the intersection between oncology and informatics. This evolving field extends beyond the scope and expertise of any single individual; oncology informatics is multi-professional by nature. The diverse editorship aims to provide balanced insights into this new and exciting area.

Machine Learning in Radiation Oncology

Machine Learning in Radiation Oncology
Theory and Applications

by Issam El Naqa,Ruijiang Li,Martin J. Murphy

  • Publisher : Springer
  • Release : 2015-06-19
  • Pages : 336
  • ISBN : 3319183052
  • Language : En, Es, Fr & De
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​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

Hendee's Radiation Therapy Physics

Hendee's Radiation Therapy Physics
A Book

by Todd Pawlicki,Daniel J. Scanderbeg,George Starkschall

  • Publisher : John Wiley & Sons
  • Release : 2016-04-18
  • Pages : 352
  • ISBN : 0470376511
  • Language : En, Es, Fr & De
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This completely updated and revised new edition of Radiation Therapy Physics contains comprehensive, balanced coverage of the fundamental radiation physics principles and its clinical applications. Since publication of the ground-breaking first edition in the 1970s, high-energy x-ray and electron beams have increasingly become the preferred approach to the radiation treatment of many cancers. Obviously, too, the use of computers has become pervasive in radiation therapy. Imaging techniques and computers are now used routinely in treatment planning, and sophisticated methods are available for overlaying anatomical images with computer generated multidimensional treatment plans. Treatment procedures such as conformal and intensity-modulated radiation therapy, high dose-rate brachytherapy, and image-guided and image-guided and adaptive radiation therapy have become standard operating procedures in radiation therapy clinics around the world. Calibration protocols have been extensively revised, and quality assurance in radiation therapy has become a subject in itself. These procedures, and others that represent state-of-the-art radiation therapy including quality engineering, are discussed at length in this new edition. The 4th edition has an increased number of chapters (20 compared to 16) and includes new topics of interest to the practicing radiation oncologist and medical physicist:- The chapter on diagnostic imaging has been expanded to include molecular imaging.- A new chapter has been added on proton radiotherapy.- A new chapter has been added on radiation oncology informatics.- A new chapter has been added on quality and safety engineering. - A new chapter on dynamic delivery techniques, explaining the standard (e.g., IMRT) and new treatment techniques (e.g., VMAT). - The treatment planning and brachytherapy chapters omit a detailed explanation of historical techniques that no one uses clinically any longer, in favor of including a new focus on modern computer-based techniques in wide-spread clinical use. - The Problem sections in each chapter have been expanded to include designated ?easy? question designed to give a broad understanding of a topic, and ?hard? questions that would be designed to help the student understand the details of a topic.

Cancer Informatics

Cancer Informatics
Essential Technologies for Clinical Trials

by John S. Silva,Marion J. Ball,Christopher G. Chute,Judith V. Douglas,Curtis P. Langlotz,Joyce C. Niland,William L. Scherlis

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 377
  • ISBN : 1461300630
  • Language : En, Es, Fr & De
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Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.

Cancer Informatics

Cancer Informatics
Essential Technologies for Clinical Trials

by John S. Silva,Marion J. Ball,Christopher G. Chute,Judith V. Douglas,Curtis Langlotz,Joyce C. Niland,William L. Scherlis

  • Publisher : Springer Science & Business Media
  • Release : 2002-01-08
  • Pages : 377
  • ISBN : 9780387953281
  • Language : En, Es, Fr & De
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Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.

UICC Manual of Clinical Oncology

UICC Manual of Clinical Oncology
A Book

by Anonim

  • Publisher : John Wiley & Sons
  • Release : 2015-07-13
  • Pages : 856
  • ISBN : 1119013135
  • Language : En, Es, Fr & De
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The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world. Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours. The ninth edition includes: Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments, Representation of multidisciplinary care for site specific management, Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines, State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy. Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

Cancer Nursing

Cancer Nursing
Principles and Practice

by Connie Henke Yarbro,Michelle Goodman,Margaret Hansen Frogge

  • Publisher : Jones & Bartlett Learning
  • Release : 2005
  • Pages : 1879
  • ISBN : 9780763747206
  • Language : En, Es, Fr & De
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Rapid changes in oncology necessitate a comprehensive, up-to-date reference for oncology nurses. For seventeen years, best-selling Cancer Nursing: Principles and Practice has filled this need, supplying oncology nurses with cutting-edge, current information. Now, in its Sixth Edition, Cancer Nursing reflects the constantly shifting progress in the science of oncology, as well as emerging new therapies, new treatment modalities, the latest results from clinical trials, updates on new chemotherapeutic agents and targeted therapies, and new perspectives on supportive care.

Essentials of Clinical Informatics

Essentials of Clinical Informatics
A Book

by Mark E. Frisse MD, MS, MBA,Karl E. Misulis MD, PhD

  • Publisher : Oxford University Press
  • Release : 2019-04-15
  • Pages : 304
  • ISBN : 0190855592
  • Language : En, Es, Fr & De
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Essentials of Clinical Informatics provides a concise and user-friendly overview on important topics such as technical infrastructure, team members and their roles, informatics methods, policies and laws, implementation, and operations. With increased interest in training and expertise in order to participate in all aspects of medical technology from basic function of electronic health record to data analytics and quality improvement to population health, this work serves as a foundational guide to better understand and analyze medical data. The book is separated into six parts: Part 1, "Areas of Focus", is an introduction to the healthcare system and healthcare information systems; Part 2, "The Framework", discusses the theoretical and procedural infrastructure of informatics, including data, knowledge, people, policies, procedures, and regulations; Part 3, "The Foundation", covers the fundamentals of clinical informatics in detail, including data representation, computer science, logic and programming, decision-making and decision support, analytics, user experience, and project management; Part 4, "Application of Informatics in Healthcare", looks at the roles of informatics in the spectrum of healthcare environments from home to hospital to population health; Part 5, "Future Trends', presents a view of future trends and methods to stay current; and Part 6, "Appendix", has reference data, glossary, case discussions, citations, recommendations for further reading, and self-assessment questions which may be of interest to professionals who are preparing for certification examinations.

Quality and Safety in Radiation Oncology

Quality and Safety in Radiation Oncology
Implementing Tools and Best Practices for Patients, Providers, and Payers

by Adam P. Dicker, MD, PhD,Eric C. Ford, PhD,Tim R. Williams, MD

  • Publisher : Springer Publishing Company
  • Release : 2016-08-17
  • Pages : 352
  • ISBN : 1617052469
  • Language : En, Es, Fr & De
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Quality and Safety in Radiation Oncology is the first book to provide an authoritative and evidence-based guide to the understanding and implementation of quality and safety procedures in radiation oncology practice. Alongside the rapid growth of technology and radiotherapy treatment options for cancer in recent years, quality and safety standards are not only of the utmost importance but best practices ensuring quality and safety are crucial aspect of modern radiation oncology training. A detailed exploration and review of these standards is a necessary part of radiation oncologist’s professional competency, both in the clinical setting and at the study table while preparing for board review and MOC exams. Chapter topics range from fundamental concepts of value and quality to commissioning technology and the use of metrics. They include perspectives on quality and safety from the patient, third-party payers, as well as from the federal government. Other chapters cover prospective testing of quality, training and education, error identification and analysis, incidence reporting, as well as special technology and procedures, including MRI-guided radiation therapy, proton therapy and stereotactic body radiation therapy (SBRT), quality and safety procedures in resource-limited environments, and more. State-of-the-art quality assurance procedures and safety guidelines are the backbone of this unique and essential volume. Physicians, medical physicists, dosimetrists, radiotherapists, hospital administrators, and other healthcare professionals will find this resource an invaluable compendium of best practices in radiation oncology. Key Features: Case examples illustrate best practices and pitfalls Several dozen graphs, tables and figures help quantify the discussion of quality and safety throughout the text Section II covers all aspects of quality assurance procedures for the physicist

Holland-Frei Cancer Medicine 8

Holland-Frei Cancer Medicine 8
A Book

by Robert C. Bast Jr,James F. Holland

  • Publisher : PMPH-USA
  • Release : 2010
  • Pages : 2021
  • ISBN : 9781607950141
  • Language : En, Es, Fr & De
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Holland Frei Cancer Medicine serves as a quick reference to current information on an extensive list of cancers, including breast, lung, thyroid, colorectal, ovarian, prostate, and gastric cancer, to name but a few. Presented as an accessible pocket-sized handbook, the chapters are organized in an outline format, offering only the most essential information on the etiology, staging (including TNM staging) and treatment for each cancer type. Individual chapters are devoted to the molecular biology of cancer, cancer prevention, cancer screening, the mechanisms of chemotherapy, and diagnostic imaging in cancer. Additionally, each chapter lists all the major phase III clinical trials, and therefore, serves as an excellent reference of the major randomized controlled trials for each cancer reported to date. Specific chapters are also dedicated to the discussion of oncologic emergencies, pain and palliation, and prescription complications. At the conclusion of the book, a glossary of oncologic terms and chemotherapeutic drug programs, a table of common cancer incidences, and an overview of the mechanisms, common uses, and related toxicities of various anti-cancer agents are featured. In addition, performance status tables, mathematical formulas and a listing of common biomedical / cancer web sites are highlighted.

IMRT, IGRT, SBRT

IMRT, IGRT, SBRT
A Book

by J.L. Meyer

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2011-05-27
  • Pages : 506
  • ISBN : 3805596812
  • Language : En, Es, Fr & De
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Over the last 4 years, IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy has become a standard reference in the field. During this time, however, significant progress in high-precision technologies for the planning and delivery of radiotherapy in cancer treatment has called for a second edition to include these new developments. Thoroughly updated and extended, this new edition offers a comprehensive guide and overview of these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity-modulated radiotherapy (IMRT), and 4D and adaptive treatment planning are clearly presented. Target localization and image-guided radiotherapy (IGRT) systems are comprehensively reviewed as well. Clinical tutorials illustrate target definitions for the major cancer sites, and useful techniques for organ motion management are described and compared. There are also several chapters that explore the technical basis and latest clinical experience with stereotactic body radiotherapy (SBRT) and summarize practical treatment recommendations. Furthermore, the significant and increasing contributions of proton therapy to cancer care are also highlighted, alongside the practical allocation of all these new technologies from an economic perspective. As a highlight of this volume, a number of images can be viewed online in time-elapse videos for greater clarity and more dynamic visualizationWritten by leading authorities in the field, this comprehensive volume brings clinical and technical practitioners of radiotherapy fully up to date with the key developments in equipment, technologies and treatment guidelines.

Cognitive Informatics in Health and Biomedicine

Cognitive Informatics in Health and Biomedicine
Understanding and Modeling Health Behaviors

by Vimla L. Patel,Jose F. Arocha,Jessica S. Ancker

  • Publisher : Springer
  • Release : 2017-05-31
  • Pages : 383
  • ISBN : 3319517325
  • Language : En, Es, Fr & De
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As health care is moving toward a team effort with patients as partners, this book provides guidance on the optimized use of health information and supporting technologies, and how people think and make decisions that affect their health and wellbeing. It focuses on investigations of how general public understand health information, assess risky behaviors, make healthcare decisions, and how they use health information technologies. e-health technologies have opened up new horizons for promoting increased self-reliance in patients. Although information technologies are now in widespread use, there is often a disparity between the scientific and technological knowledge underlying health care practices and the cultural beliefs, mental models, and cognitive representations of illness and disease. Misconceptions based on inaccurate perceptions and mental models, and flawed prior beliefs could lead to miscommunication as well as to erroneous decisions about individuals’ own health or the health of their family members. Cognitive Informatics in Health and Biomedicine: Understanding and Modeling Health Behaviors presents state of the art research in cognitive informatics for assessing the impact of patient behaviour. It is designed to assist all involved at the intersection of the health care institution and the patient and covers contributions from recognized researchers and leaders in the field.

Biomedical Informatics

Biomedical Informatics
A Book

by Andreas Holzinger

  • Publisher : BoD – Books on Demand
  • Release : 2012
  • Pages : 368
  • ISBN : 3848222191
  • Language : En, Es, Fr & De
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Medical Informatics is defined as the interdisciplinary field that studies and pursues the effective use of biomedical data, information and knowledge for scientific inquiry, problem solving, and decision making, motivated by efforts to improve human health. To emphasize the broad character it is called Biomedical Informatics. The aim of this course is to provide a student with a broad overview with focus on data, information and knowledge. The course consists of the following 12 lectures: 1. Introduction: Computer Science meets Life Sciences, challenges and future directions; 2. Back to the future: Fundamentals of Data, Information and Knowledge; 3. Structured Data: Coding, Classification (ICD, SNOMED, MeSH, UMLS); 4. Biomedical Databases: Acquisition, Storage, Information Retrieval and Use; 5. Semi structured and weakly structured data (structural homologies); 6. Multimedia Data Mining and Knowledge Discovery; 7. Knowledge and Decision: Cognitive Science and Human-Computer Interaction; 8. Biomedical Decision Making: Reasoning and Decision Support; 9. Intelligent Information Visualization and Visual Analytics; 10. Biomedical Information Systems and Medical Knowledge Management; 11. Biomedical Data: Privacy, Safety and Security 12. Methodology for Information Systems: System Design, Usability and Evaluation

Issues in Information Science: Informatics: 2011 Edition

Issues in Information Science: Informatics: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 520
  • ISBN : 1464966206
  • Language : En, Es, Fr & De
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Issues in Information Science: Informatics / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Information Science—Informatics. The editors have built Issues in Information Science: Informatics: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Information Science—Informatics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Information Science: Informatics / 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biomedical Informatics for Cancer Research

Biomedical Informatics for Cancer Research
A Book

by Michael F. Ochs,John T. Casagrande,Ramana V. Davuluri

  • Publisher : Springer Science & Business Media
  • Release : 2010-04-06
  • Pages : 354
  • ISBN : 1441957146
  • Language : En, Es, Fr & De
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view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant proteins, since any tre- ment must aim to improve health to justify its potential side effects. Treatment for cancer must become highly individualized, focusing on the specific aberrant driver proteins in an individual. This drives a need for informatics in cancer far beyond the need in other diseases. For instance, routine treatment with statins has become widespread for minimizing heart disease, with most patients responding to standard doses (Wilt et al. 2004). In contrast, standard treatment for cancer must become tailored to the molecular phenotype of an individual tumor, with each patient receiving a different combination of therapeutics aimed at the specific aberrant proteins driving the cancer. Tracking the aberrations that drive cancers, identifying biomarkers unique to each individual for molecular-level di- nosis and treatment response, monitoring adverse events and complex dosing schedules, and providing annotated molecular data for ongoing research to improve treatments comprise a major biomedical informatics need.

IMRT, IGRT, SBRT

IMRT, IGRT, SBRT
Advances in the Treatment Planning and Delivery of Radiotherapy

by John Meyer

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2007-01-01
  • Pages : 437
  • ISBN : 3805581998
  • Language : En, Es, Fr & De
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New high-precision technologies for the planning and delivery of radiotherapy are major advances in cancer treatment. This volume is a comprehensive guidebook to these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity modulated radiation therapy (IMRT), 4D and adaptive treatment planning are clearly explained, and the new target localization and image-guided radiotherapy (IGRT) systems are comprehensively reviewed. Clinical tutorials fully illustrate the target definitions for the major cancer sites, and techniques for organ motion management are shown. In addition, chapters explore the technical basis for stereotactic body radiotherapy (SBRT) and the latest clinical experience with it for most organ sites.