Download Oral Delivery of Insulin Ebook PDF

Oral Delivery of Insulin

Oral Delivery of Insulin
A Book

by T.A. Sonia,Chandra P. Sharma

  • Publisher : Elsevier
  • Release : 2014-12-11
  • Pages : 290
  • ISBN : 1908818689
  • Language : En, Es, Fr & De
GET BOOK

Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field

Oral Delivery of Insulin

Oral Delivery of Insulin
A Book

by T. A. Sonia,Chandra P. Sharma

  • Publisher : Woodhead Publishing
  • Release : 2017-11-13
  • Pages : 270
  • ISBN : 9780081016251
  • Language : En, Es, Fr & De
GET BOOK

Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes MellitusIncludes a discussion of various strategies and techniques adopted for oral delivery of insulinPresents an update of research in the field

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
A Book

by Ali Demir Sezer

  • Publisher : BoD – Books on Demand
  • Release : 2014-07-25
  • Pages : 554
  • ISBN : 9535116282
  • Language : En, Es, Fr & De
GET BOOK

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Novel Drug Delivery Systems for the Delivery of Insulin

Novel Drug Delivery Systems for the Delivery of Insulin
A Book

by Radhika Narain

  • Publisher : Unknown Publisher
  • Release : 2016-09-15
  • Pages : 20
  • ISBN : 9783668297074
  • Language : En, Es, Fr & De
GET BOOK

Scientific Study from the year 2014 in the subject Medicine - Pharmacology, grade: A, language: English, abstract: The delivery of proteins is challenging due to their high molecular weight and hydrophilic structures, making them difficult to cross the ubiquitous lipidic membranes. Proteins have a unique structure which makes them suited to a unique function, therefore, maintenance of the structural integrity and stability of these macromolecules is also of a high concern as they can easily be denatured by temperature, pH and other physiochemical changes. The protein and peptide delivery systems have to be designed in a way such that the drug carriers can protect the protein from proteases, increase its permeability through membranes, increase its absorption and bioavailability, sustain its release, with low dosage requirements and, increase its systemic circulation. The study presents the delivery of insulin through various routes: buccal, transdermal, oral and pulmonary, utilizing different novel carriers like polymeric nanoparticles, solid lipid nanoparticles, liposomes, nanoshells, nanospheres and nanoparticles encapsulated in microparticles, along with drug surface modification either by attaching peptide ligands or conjugating with polymers to enhance absorption and targeting capacity of the drug.

Oral Controlled Release Formulation Design and Drug Delivery

Oral Controlled Release Formulation Design and Drug Delivery
Theory to Practice

by Hong Wen,Kinam Park

  • Publisher : John Wiley & Sons
  • Release : 2011-01-14
  • Pages : 376
  • ISBN : 9781118060322
  • Language : En, Es, Fr & De
GET BOOK

This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Oral Colon-Specific Drug Delivery

Oral Colon-Specific Drug Delivery
A Book

by David R. Friend

  • Publisher : CRC Press
  • Release : 1992-07-27
  • Pages : 288
  • ISBN : 9780849366888
  • Language : En, Es, Fr & De
GET BOOK

Oral Colon-Specific Drug Delivery covers approaches used to deliver a variety of drugs to the colon. Anatomy and physiology of the gastrointestinal tract as it affects colonic drug delivery and pharmacokinetics are reviewed, as well as drug absorption from the colon. The book presents valuable information on a variety of topics, including oral peptide/protein delivery, dextran-based delivery systems, glycoside/glycosidase-based delivery, azo-bond prodrugs, hydroxypropyl methacrylamide copolymers for colonic delivery, and matrices for colonic drug delivery. Special emphasis is placed on delivery systems, especially biochemical approaches to delivery, such as the use of degradable polymers and both low and high molecular weight prodrugs. Oral Colon-Specific Drug Delivery will provide a valuable reference resource for gastroenterologists, pharmaceutical scientists, and other researchers working with drug delivery to the colon.

Drug Delivery Systems

Drug Delivery Systems
A Book

by Vasant V. Ranade,Mannfred A. Hollinger,John B. Cannon

  • Publisher : CRC Press
  • Release : 2003-08-26
  • Pages : 464
  • ISBN : 9781420040142
  • Language : En, Es, Fr & De
GET BOOK

Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both

Drug Delivery Nanoparticles Formulation and Characterization

Drug Delivery Nanoparticles Formulation and Characterization
A Book

by Yashwant Pathak,Deepak Thassu

  • Publisher : CRC Press
  • Release : 2016-04-19
  • Pages : 416
  • ISBN : 1420078054
  • Language : En, Es, Fr & De
GET BOOK

Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
A Book

by Ali Demir Sezer

  • Publisher : BoD – Books on Demand
  • Release : 2014-07-25
  • Pages : 554
  • ISBN : 9535116282
  • Language : En, Es, Fr & De
GET BOOK

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Drug Delivery

Drug Delivery
An Integrated Clinical and Engineering Approach

by Yitzhak Rosen,Pablo Gurman,Noel Elman

  • Publisher : CRC Press
  • Release : 2017-09-19
  • Pages : 602
  • ISBN : 1466565950
  • Language : En, Es, Fr & De
GET BOOK

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

Drug Delivery

Drug Delivery
Engineering Principles for Drug Therapy

by W. Mark Saltzman

  • Publisher : Oxford University Press
  • Release : 2001-03-15
  • Pages : 384
  • ISBN : 9780198024699
  • Language : En, Es, Fr & De
GET BOOK

Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

Mucosal Delivery of Biopharmaceuticals

Mucosal Delivery of Biopharmaceuticals
Biology, Challenges and Strategies

by José das Neves,Bruno Sarmento

  • Publisher : Springer Science & Business Media
  • Release : 2014-02-03
  • Pages : 601
  • ISBN : 1461495245
  • Language : En, Es, Fr & De
GET BOOK

Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing biopharmaceuticals for mucosal delivery, with a focus on the most successful case studies of recent years. The last section briefly centers on relevant aspects of the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals.​ Scientists and researchers in the fields of drug delivery, material science, biomedical science and bioengineering as well as professionals, regulators and policy makers in the pharmaceutical, biotechnology and healthcare industries will find in this book an important compendium of fundamental concepts and practical tools for their daily research and activities.

Controlled Drug Delivery Systems

Controlled Drug Delivery Systems
A Book

by Emmanuel C. Opara

  • Publisher : CRC Press
  • Release : 2020-02-28
  • Pages : 351
  • ISBN : 0429584652
  • Language : En, Es, Fr & De
GET BOOK

This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.

Novel Drug Delivery Systems for Phytoconstituents

Novel Drug Delivery Systems for Phytoconstituents
A Book

by Madhu Gupta,Durgesh Nandini Chauhan,Vikas Sharma,Nagendra Singh Chauhan

  • Publisher : CRC Press
  • Release : 2019-07-23
  • Pages : 336
  • ISBN : 1351057618
  • Language : En, Es, Fr & De
GET BOOK

Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment
A Book

by Jorge Coelho

  • Publisher : Springer Science & Business Media
  • Release : 2013-03-15
  • Pages : 421
  • ISBN : 9400760108
  • Language : En, Es, Fr & De
GET BOOK

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Drug Delivery Devices and Therapeutic Systems

Drug Delivery Devices and Therapeutic Systems
A Book

by Eric Chappel

  • Publisher : Academic Press
  • Release : 2020-11-07
  • Pages : 678
  • ISBN : 0128198397
  • Language : En, Es, Fr & De
GET BOOK

Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. Provides essential information on the most recent drug delivery systems available Explains current technology and its applications to drug delivery Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers

Nanoscience in Medicine

Nanoscience in Medicine
A Book

by Hemant Kumar Daima,Navya PN,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse

  • Publisher : Springer Nature
  • Release : 2020-01-10
  • Pages : 494
  • ISBN : 303029207X
  • Language : En, Es, Fr & De
GET BOOK

This book takes a systematic approach to address the gaps relating to nanomedicine and bring together fragmented knowledge on the advances on nanomaterials and their biomedical applicability. In particular, it demonstrates an exclusive compilation of state of the art research with a focus on fundamental concepts, current trends, limitations, and future directions of nanomedicine.

Polymeric Drug Delivery

Polymeric Drug Delivery
A Book

by Sönke Svenson

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Industrial Applications of Microemulsions

Industrial Applications of Microemulsions
A Book

by Conxita Solans,Hironobu Kunieda

  • Publisher : CRC Press
  • Release : 1996-11-27
  • Pages : 424
  • ISBN : 9780824797959
  • Language : En, Es, Fr & De
GET BOOK

"Fills a void in the literature by presenting the basic concepts of microemulsions, essential to understanding their industrial significance, and comprehensive descriptions of the most useful commerical applications. Discusses important issues related to enzymatic reactions and nanoparticle formation. Charts the enormous advances that have occurred in the field over the past decade."

Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery
Proceedings of a Symposium Held at the Royal Danish Academy of Sciences and Letters, August 17-21, 1997

by Sven Frøkjær

  • Publisher : Munksgaard International Publishers
  • Release : 1998
  • Pages : 483
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK