Download Plotkin’s Vaccines Ebook PDF

Vaccines

Vaccines
A Book

by Stanley A. Plotkin,Walter A. Orenstein,Paul A. Offit

  • Publisher : Unknown Publisher
  • Release : 2017-09-01
  • Pages : 329
  • ISBN : 9780323357616
  • Language : En, Es, Fr & De
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Vaccines

Vaccines
A Book

by Stanley A. Plotkin,Walter Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2008-02-11
  • Pages : 1748
  • ISBN : 1437721583
  • Language : En, Es, Fr & De
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Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.

History of Vaccine Development

History of Vaccine Development
A Book

by Stanley A. Plotkin

  • Publisher : Springer Science & Business Media
  • Release : 2011-05-11
  • Pages : 349
  • ISBN : 9781441913395
  • Language : En, Es, Fr & De
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Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

Vaccines

Vaccines
A Book

by Stanley A. Plotkin,Walter A. Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2008
  • Pages : 1725
  • ISBN : 1416036113
  • Language : En, Es, Fr & De
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Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination--from development to use in reducing disease. It also includes access to a companion Web site for more coverage.

Plotkin's Vaccines

Plotkin's Vaccines
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Vaccines E-Book

Vaccines E-Book
A Book

by Stanley A. Plotkin,Walter Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2012-09-22
  • Pages : 1570
  • ISBN : 1455737984
  • Language : En, Es, Fr & De
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Apply the latest vaccination knowledge with a reference that Bill Gates calls "an indispensable guide to the enhancement of the well-being of our world." Inside Vaccines, you’ll find comprehensive and current coverage of every aspect of vaccination, from the development of each vaccine to its use in reducing disease. This medical reference book offers the expert information you need to apply the very latest techniques and information in your practice! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Gain a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Update your knowledge of both existing vaccines and vaccines currently in the research and development stage. Get complete answers on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyze the cost-benefit and cost-effectiveness of different vaccine options. Clearly visualize concepts and objective data through an abundance of tables and figures. Make optimal use of the latest vaccines for pneumococcal disease, rotavirus, human papillomavirus, herpes zoster, meningococcal disease, and much more. Stay at the forefront of new developments with completely updated chapters on malaria and HIV vaccines, a new chapter on vaccine regulations across the world, and many other revisions throughout.

Plotkin on Vaccines

Plotkin on Vaccines
A Book

by Stanley A Plotkin

  • Publisher : Independently Published
  • Release : 2019-05-28
  • Pages : 200
  • ISBN : 9781070693354
  • Language : En, Es, Fr & De
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Known as the "Godfather of Vaccines", Stanley A Plotkin is the world-renowned American physician who works as a consultant to vaccine manufacturers, such as Sanofi Pasteur, as well as biotechnology firms, non-profits and governments. In the 1960s, he played a pivotal role in discovery of a vaccine against rubella virus while working at Wistar Institute in Philadelphia. Plotkin was a member of Wistar's active research faculty from 1960 to 1991. Today, in addition to his emeritus appointment at Wistar, he is emeritus professor of Pediatrics at the University of Pennsylvania. His book, "Vaccines", is the standard reference on the subject. He is an editor with Clinical and Vaccine Immunology, which is published by the American Society for Microbiology in Washington, D.C.He is known to be the foremost expert on vaccines and immunology and offered his wealth of knowledge as an expert witness for a court case in Michigan. This is an unprecedented look into the mind of perhaps the most knowledgeable authority in the field in an honest and thorough interview.

The Vaccine Race

The Vaccine Race
Science, Politics, and the Human Costs of Defeating Disease

by Meredith Wadman

  • Publisher : Penguin
  • Release : 2017-02-07
  • Pages : 464
  • ISBN : 0698177789
  • Language : En, Es, Fr & De
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“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature “This is a story about the war against disease—a war without end—and the development of enormously important vaccines, but in telling that story, in showing how science works, Meredith Wadman reveals much more. I loved this book.” —John M. Barry, New York Times bestselling author of The Great Influenza The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

Mass Vaccination: Global Aspects - Progress and Obstacles

Mass Vaccination: Global Aspects - Progress and Obstacles
A Book

by Stanley A. Plotkin

  • Publisher : Springer Science & Business Media
  • Release : 2006-09-21
  • Pages : 274
  • ISBN : 3540365834
  • Language : En, Es, Fr & De
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Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.

Adverse Effects of Vaccines

Adverse Effects of Vaccines
Evidence and Causality

by Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines

  • Publisher : National Academies Press
  • Release : 2012-04-26
  • Pages : 894
  • ISBN : 0309214351
  • Language : En, Es, Fr & De
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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Vaccines Did Not Cause Rachel's Autism

Vaccines Did Not Cause Rachel's Autism
My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad

by Peter J. Hotez

  • Publisher : Johns Hopkins University Press
  • Release : 2021-01-05
  • Pages : 240
  • ISBN : 1421439808
  • Language : En, Es, Fr & De
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"—from the foreword by Arthur L. Caplan, NYU School of Medicine

Vaccine

Vaccine
The Controversial Story of Medicine's Greatest Lifesaver

by Arthur Allen

  • Publisher : W W Norton & Company Incorporated
  • Release : 2008
  • Pages : 523
  • ISBN : 9780393331561
  • Language : En, Es, Fr & De
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A definitive history of vaccination ranges from Edward Jenner's 1796 creation of the world's first smallpox inoculation to the present day, looking at both the benefits of vaccination as well as the current controversy over their potential neurological side effects and the pharmaceutical companies' emphasis on treatment rather than prevention. Reprint.

Vaccinia, Vaccination, Vaccinology

Vaccinia, Vaccination, Vaccinology
Jenner, Pasteur and Their Successors

by Stanley A. Plotkin,Bernardino Fantini

  • Publisher : Elsevier Science Limited
  • Release : 1996
  • Pages : 379
  • ISBN : 9782906077836
  • Language : En, Es, Fr & De
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Preclinical and Clinical Development of New Vaccines

Preclinical and Clinical Development of New Vaccines
Institut Pasteur, Paris, France 27-28 May 1997

by Stanley A. Plotkin,Fred Brown,Florian Horaud

  • Publisher : S Karger Ag
  • Release : 1998
  • Pages : 280
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This publication covers all aspects of new vaccine development from the preclinical stage to licensing. It contains discussions about the preclinical testing which is necessary to obtain permission to test a new vaccine in clinical trials and to organize a clinical plan that will demonstrate the safety and efficacy of a new vaccine. In addition, some aspects of newer strategies, such as DNA immunization, are presented as well as a number of theoretical issues relating to vaccination, such as immunological correlates of protection, interference with immune responses, combination of vaccines, and the natural history of disease. Much attention is devoted to the proof of efficacy, a process which is both expensive and complicated. This volume is important reading for all scientists interested in vaccine development, especially those working in industry, government and public health authorities.

The Vaccine Book

The Vaccine Book
A Book

by Barry R. Bloom,Paul-Henri Lambert

  • Publisher : Academic Press
  • Release : 2016-06-23
  • Pages : 664
  • ISBN : 012805400X
  • Language : En, Es, Fr & De
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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy

Vaccinology

Vaccinology
Principles and Practice

by W. John W. Morrow,Nadeem A. Sheikh,Clint S. Schmidt,D. Huw Davies

  • Publisher : John Wiley & Sons
  • Release : 2012-06-12
  • Pages : 552
  • ISBN : 1118345347
  • Language : En, Es, Fr & De
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Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.

Peptide and Protein Vaccines

Peptide and Protein Vaccines
A Book

by Rossen Donev

  • Publisher : Academic Press
  • Release : 2015-06-08
  • Pages : 192
  • ISBN : 0128028696
  • Language : En, Es, Fr & De
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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Vaccination Ethics and Policy

Vaccination Ethics and Policy
An Introduction with Readings

by Jason Lee Schwartz,Arthur L. Caplan

  • Publisher : Mit Press
  • Release : 2016-04-12
  • Pages : 432
  • ISBN : 9780262035330
  • Language : En, Es, Fr & De
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"Vaccination has long been a familiar, highly effective form of medicine and a triumph of public health. Because vaccination is both an individual medical intervention and a central component of public health efforts, it raises a distinct set of legal and ethical issues--from debates over their risks and benefits to the use of government vaccination requirements--and makes vaccine policymaking uniquely challenging. This volume examines the full range of ethical and policy issues related to the development and use of vaccines in the United States and around the world. Forty essays, articles, and reports by experts in the field look at all aspects of the vaccine life cycle. After an overview of vaccine history, they consider research and development, regulation and safety, vaccination promotion and requirements, pandemics and bioterrorism, and the frontier of vaccination. The texts cover such topics as vaccine safety controversies; the ethics of vaccine trials; vaccine injury compensation; vaccine refusal and the risks of vaccine-preventable diseases; equitable access to vaccines in emergencies; lessons from the eradication of smallpox; and possible future vaccines against cancer, malaria, and Ebola. The volume intentionally includes texts that take opposing viewpoints, offering readers a range of arguments. The book will be an essential reference for professionals, scholars, and students."--

Adverse Effects of Pertussis and Rubella Vaccines

Adverse Effects of Pertussis and Rubella Vaccines
A Book

by Institute of Medicine,Committee to Review the Adverse Consequences of Pertussis and RubellaVaccines

  • Publisher : National Academies Press
  • Release : 1991-01-01
  • Pages : 382
  • ISBN : 0309044995
  • Language : En, Es, Fr & De
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Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.

Disease Control Priorities, Third Edition (Volume 2)

Disease Control Priorities, Third Edition (Volume 2)
Reproductive, Maternal, Newborn, and Child Health

by Robert Black,Ramanan Laxminarayan,Marleen Temmerman,Neff Walker

  • Publisher : World Bank Publications
  • Release : 2016-04-11
  • Pages : 416
  • ISBN : 1464803684
  • Language : En, Es, Fr & De
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The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.