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Digital Personalized Health and Medicine

Digital Personalized Health and Medicine
Proceedings of MIE 2020

by L.B. Pape-Haugaard,C. Lovis,I. Cort Madsen

  • Publisher : IOS Press
  • Release : 2020-06-17
  • Pages : 1496
  • ISBN : 1643680838
  • Language : En, Es, Fr & De
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Digital health and medical informatics have grown in importance in recent years, and have now become central to the provision of effective healthcare around the world. This book presents the proceedings of the 30th Medical Informatics Europe conference (MIE). This edition of the conference, hosted by the European Federation for Medical Informatics (EFMI) since the 1970s, was due to be held in Geneva, Switzerland in April 2020, but as a result of measures to prevent the spread of the Covid19 pandemic, the conference itself had to be cancelled. Nevertheless, because this collection of papers offers a wealth of knowledge and experience across the full spectrum of digital health and medicine, it was decided to publish the submissions accepted in the review process and confirmed by the Scientific Program Committee for publication, and these are published here as planned. The 232 papers are themed under 6 section headings: biomedical data, tools and methods; supporting care delivery; health and prevention; precision medicine and public health; human factors and citizen centered digital health; and ethics, legal and societal aspects. A 7th section deals with the Swiss personalized health network, and section 8 includes the 125 posters accepted for the conference. Offering an overview of current trends and developments in digital health and medical informatics, the book provides a valuable information resource for researchers and health practitioners alike.

Precision Medicine

Precision Medicine
Tools and Quantitative Approaches

by Hans-Peter Deigner,Matthias Kohl

  • Publisher : Academic Press
  • Release : 2018-02-15
  • Pages : 374
  • ISBN : 0128054336
  • Language : En, Es, Fr & De
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Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature

Precision Medicine in Oncology

Precision Medicine in Oncology
A Book

by Bulent Aydogan,James A. Radosevich

  • Publisher : John Wiley & Sons
  • Release : 2020-09-23
  • Pages : 288
  • ISBN : 1119432448
  • Language : En, Es, Fr & De
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A FRESH EXAMINATION OF PRECISION MEDICINE'S INCREASINGLY PROMINENT ROLE IN THE FIELD OF ONCOLOGY Precision medicine takes into account each patient's specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice. Precision Medicine in Oncology draws together the essential research driving the field forward, providing oncology clinicians and trainees alike with an illuminating overview of the technology and thinking behind the breakthroughs currently being made. Topics covered include: Biologically-guided radiation therapy Informatics for precision medicine Molecular imaging Biomarkers for treatment assessment Big data Nanoplatforms Casting a spotlight on this emerging knowledge base and its impact upon the management of tumors, Precision Medicine in Oncology opens up new possibilities and ways of working – not only for oncologists, but also for molecular biologists, radiologists, medical geneticists, and others.

Precision Medicine: A Guide to Genomics in Clinical Practice

Precision Medicine: A Guide to Genomics in Clinical Practice
A Book

by Jeanette J. McCarthy,Bryce A. Mendelsohn

  • Publisher : McGraw Hill Professional
  • Release : 2017-01-05
  • Pages : 304
  • ISBN : 1259644146
  • Language : En, Es, Fr & De
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Incorporate genomics into every applicable area of your clinical practice with this complete how-to guide Precision Medicine: A Guide to Genomics in Clinical Practice is a comprehensive, yet succinct overview of the practice of genomic medicine. It is written for general healthcare practitioners, specialists, and trainees with the goal of providing detailed guidance on how to incorporate genomic medicine into daily practice. Features that make this book valuable to every practice: •Intentionally avoids excessive technical content and consistently emphasizes real-life patient care and decision support •Follows the course of a human life, beginning before conception through pregnancy, childhood, and adulthood, discussing the current and future applications of genomics and precision medicine at each stage •Organization allows healthcare providers to quickly and easily find the information relevant to their practice. •The authors highlight common pitfalls – technical and ethical – that might complicate the delivery of quality genomic healthcare •Enhanced by eleven valuable appendices that cover important topics ranging from the basics of genetics to ethical issues to regulation and reimbursement If you are searching for a clinically relevant, non-technical resource that will teach you how genomic medicine can and should be practiced in your specific field of interest, Precision Medicine: A Guide to Genomics in Clinical Practicebelongs on your desk.

Genomic and Precision Medicine

Genomic and Precision Medicine
Primary Care

by Geoffrey S. Ginsburg,Huntington F Willard,Sean P. David

  • Publisher : Academic Press
  • Release : 2017-03-30
  • Pages : 370
  • ISBN : 0128006544
  • Language : En, Es, Fr & De
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Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners. Presents a comprehensive volume for primary care providers Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine Includes a current overview on major opportunities for genomic and personalized medicine in practice Highlights case studies that illustrate the practical use of genomics in the management in patients

Precision Medicine: A Multidisciplinary Approach , EBK

Precision Medicine: A Multidisciplinary Approach , EBK
Clinics Collections

by Joel J. Heidelbaugh

  • Publisher : Elsevier Health Sciences
  • Release : 2020-12-18
  • Pages : 240
  • ISBN : 032378948X
  • Language : En, Es, Fr & De
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The Clinics Collections titles take a multidisciplinary approach to today’s practice of medicine, selecting the most recent and relevant articles from the Clinics series and combining them into a single source of information on a focused topic. Articles are chosen from multiple Clinics to highlight the range of specialties covering major medical issues, delivering the information needed for successful interdisciplinary teamwork and effective patient care. Written from a variety of medical perspectives, these articles offer deeper insight into how each specialty cares for its patients and provide a unique entry into sharing best concepts for the entire medical team. Clinics Collections: Precision Medicine draws from Elsevier’s Clinics Review Articles database to provide today’s medical teams with practical clinical advice and insights on this timely medical model. It guides readers on how to apply current primary research findings to everyday practice, keep up with new and improved treatment methods, and improve patient outcomes. Areas of focus include breast cancer, lung cancer, melanoma, arthritis, sleep medicine, and pediatric oncology. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format.

Enabling Precision Medicine

Enabling Precision Medicine
The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop

by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Roundtable on Genomics and Precision Health,Forum on Drug Discovery, Development, and Translation

  • Publisher : National Academies Press
  • Release : 2017-11-17
  • Pages : 144
  • ISBN : 0309462630
  • Language : En, Es, Fr & De
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Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop.

Animal Biotechnology

Animal Biotechnology
Models in Discovery and Translation

by Ashish S. Verma,Anchal Singh

  • Publisher : Academic Press
  • Release : 2020-07-03
  • Pages : 798
  • ISBN : 0128117109
  • Language : En, Es, Fr & De
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Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Precision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers
A Book

by Joel Faintuch,Salomao Faintuch

  • Publisher : Academic Press
  • Release : 2019-11-16
  • Pages : 640
  • ISBN : 0128191791
  • Language : En, Es, Fr & De
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Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

The Road from Nanomedicine to Precision Medicine

The Road from Nanomedicine to Precision Medicine
A Book

by Shaker A. Mousa,Raj Bawa,Gerald F. Audette

  • Publisher : CRC Press
  • Release : 2020-01-13
  • Pages : 1208
  • ISBN : 1000021270
  • Language : En, Es, Fr & De
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The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Precision Sleep Medicine, An Issue of Sleep Medicine Clinics - Ebook

Precision Sleep Medicine, An Issue of Sleep Medicine Clinics - Ebook
A Book

by Susheel Patil

  • Publisher : Elsevier Health Sciences
  • Release : 2019-08-07
  • Pages : 329
  • ISBN : 0323682634
  • Language : En, Es, Fr & De
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This issue of Sleep Medicine Clinics, edited by Dr. Susheel Patil in collaboration with Consulting Editor, Teogilo Lee-Chiong, is devoted to Precision Sleep Medicine. Topics covered in this issue include: The Promise of Precision Medicine in Sleep Medicine; Precision Medicine for Obstructive Sleep Apnea; Precision Medicine for Pediatric Obstructive Sleep Apnea; Precision Medicine for Hypersomnia; Precision Medicine for Insomnia; iCBTi: Tailoring CBTi for Chronic Insomnia Patients; Sleep Loss; Precision Medicine for REM Behavior Disorder; NREM Parasomnia: The Promise of Precision Medicine; Sleep Pharmacogenetics: The Promise of Precision Medicine; and Sleep and Memory: The Promise of Precision Medicine.

Progress and Challenges in Precision Medicine

Progress and Challenges in Precision Medicine
A Book

by Mukesh Verma,Debmalya Barh

  • Publisher : Academic Press
  • Release : 2016-12-22
  • Pages : 344
  • ISBN : 0128095024
  • Language : En, Es, Fr & De
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Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine

Machine Learning Advanced Dynamic Omics Data Analysis for Precision Medicine
A Book

by Tao Zeng,Tao Huang,Chuan Lu

  • Publisher : Frontiers Media SA
  • Release : 2020-03-30
  • Pages : 329
  • ISBN : 2889635546
  • Language : En, Es, Fr & De
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Precision Medicine in Stroke

Precision Medicine in Stroke
A Book

by Ana Catarina Fonseca

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 303070761X
  • Language : En, Es, Fr & De
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The Patient Equation

The Patient Equation
The Precision Medicine Revolution in the Age of COVID-19 and Beyond

by Glen de Vries

  • Publisher : John Wiley & Sons
  • Release : 2020-09-16
  • Pages : 288
  • ISBN : 111962214X
  • Language : En, Es, Fr & De
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How the data revolution is transforming biotech and health care, especially in the wake of COVID-19—and why you can’t afford to let it pass you by We are living through a time when the digitization of health and medicine is becoming a reality, with new abilities to improve outcomes for patients as well as the efficiency and success of the organizations that serve them. In The Patient Equation, Glen de Vries presents the history and current state of life sciences and health care as well as crucial insights and strategies to help scientists, physicians, executives, and patients survive and thrive, with an eye toward how COVID-19 has accelerated the need for change. One of the biggest challenges facing biotech, pharma, and medical device companies today is how to integrate new knowledge, new data, and new technologies to get the right treatments to the right patients at precisely the right times—made even more profound in the midst of a pandemic and in the years to come. Drawing on the fascinating stories of businesses and individuals that are already making inroads—from a fertility-tracking bracelet changing the game for couples looking to get pregnant, to an entrepreneur reinventing the treatment of diabetes, to Medidata's own work bringing clinical trials into the 21st century—de Vries shares the breakthroughs, approaches, and practical business techniques that will allow companies to stay ahead of the curve and deliver solutions faster, cheaper, and more successfully—while still upholding the principles of traditional therapeutic medicine and reflecting the current environment. How new approaches to cancer and rare diseases are leading the way toward precision medicine What data and digital technologies enable in the building of robust, effective disease management platforms Why value-based reimbursement is changing the business of life sciences How the right alignment of incentives will improve outcomes at every stage of the patient journey Whether you're a scientist, physician, or executive, you can't afford to let the moment pass: understand the landscape with this must-read roadmap for success—and see how you can change health care for the better.

Bioscience - Lost in Translation?

Bioscience - Lost in Translation?
How Precision Medicine Closes the Innovation Gap

by Richard Barker

  • Publisher : Oxford University Press
  • Release : 2016-09-01
  • Pages : 240
  • ISBN : 0198737785
  • Language : En, Es, Fr & De
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Medical innovation as it stands today is fundamentally unsustainable. There is a widening gap between what biomedical research promises and the impact that it is currently achieving, in terms of patient benefit and health system improvement. This book highlights the global problem of the ineffective translation of bioscience innovation into health system improvements and its consequences, analyses the underlying causative factors and provides powerful prescriptions for change to close the gap. It contrasts the progress in biomedicine with other areas of scientific and technological endeavour, such as information technology, in which there are faster and more reliable returns for society from scientific advance. It asks searching questions about whether society is right to expect so much from biomedicine and why we have become accustomed to such poor returns. Throughout the book, techniques such as stratified medicine, open innovation, adaptive development and personalised adherence are discussed and described in terms accessible to the non-specialist, and their impact on the innovation gap explored. By using examples in which bottlenecks have prevented progress, such as dementia and antibiotic-resistant infections, and in which these barriers have been overcome, such as HIV treatment, Bioscience - Lost in Translation? lays out a strategy for advancing the innovation process, presenting suggestions for how health systems can move from being passive recipients of innovation to being active participants in development.

Toward Precision Medicine

Toward Precision Medicine
Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease

by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease

  • Publisher : National Academies Press
  • Release : 2012-01-16
  • Pages : 142
  • ISBN : 0309222222
  • Language : En, Es, Fr & De
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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Adaptive Health Management Information Systems

Adaptive Health Management Information Systems
A Book

by Joseph Tan

  • Publisher : Jones & Bartlett Learning
  • Release : 2019-09-17
  • Pages : 490
  • ISBN : 1284153894
  • Language : En, Es, Fr & De
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Adaptive Health Management Information Systems, Fourth Edition is a thorough resource for a broad range of healthcare professionals-from informaticians, physicians and nurses, to pharmacists, public health and allied health professionals-who need to keep pace the digital transformation of health care. Wholly revised, updated, and expanded in scope, the fourth edition covers the latest developments in the field of health management information systems (HMIS) including big data analytics and machine learning in health care; precision medicine; digital health commercialization; supply chain management; informatics for pharmacy and public health; digital health leadership; cybersecurity; and social media analytics.

Precision Medicine Oncology

Precision Medicine Oncology
A Primer

by Lorna Rodriguez-Rodriguez

  • Publisher : Rutgers University Press
  • Release : 2019-09-13
  • Pages : 122
  • ISBN : 0813575885
  • Language : En, Es, Fr & De
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Precision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. This is made possible, in part, by the ready availability and reasonable costs of comprehensive DNA and RNA sequencing assays. However, precision medicine is complex and incorporates entirely new types of data and treatment paradigms that are outside of the training of most oncologists in practice today. Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, intended for clinicians, particularly those working in oncology. It provides an accessible introduction to the technological advances in DNA and RNA sequencing, gives a detailed overview of approaches to the interpretation of molecular test results and their point-of-care implementation for individual patients, and describes innovative clinical trial designs in oncology as well as characteristics of the computational infrastructures through which massive quantities of data are collected, stored, and used in precision medicine oncology.

Precision Medicine

Precision Medicine
A Book

by Tao Huang

  • Publisher : Humana
  • Release : 2020-08-25
  • Pages : 226
  • ISBN : 9781071609033
  • Language : En, Es, Fr & De
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This book serves to introduce the technologies and applications of precision medicine. Beginning with a section on emerging experimental and bioinformatics technologies, the collection continues with chapters covering cancer studies, cardiovascular diseases, COPD and systemic lupus erythematosus, as well as the latest engineering and surgical developments in precision medicine. As a volume in the highly successful Methods in Molecular Biology series, this book presents key information from experts in the field. Authoritative and cutting-edge, Precision Medicine covers perspectives of precision medicine from basic research to clinical surgeries, from cancer to cardiovascular disease, from sequencing technology to big data analysis in the hope of broadening the horizons for researchers, engineers, and clinicians and accelerating the interdisciplinary precision medicine research and applications.