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Recent Advances in Applications of Name Reactions in Multicomponent Reactions

Recent Advances in Applications of Name Reactions in Multicomponent Reactions
A Book

by Majid M. Heravi,Vahideh Zadsirjan

  • Publisher : Elsevier
  • Release : 2020-05-29
  • Pages : 438
  • ISBN : 0128196955
  • Language : En, Es, Fr & De
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Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs. These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described. Includes the synthesis of many heterocycles, which is ideal for synthetic organic chemists engaged in the synthesis of heterocyclic systems Covers the recent advances of asymmetric synthesis of a wide range of heterocycles in satisfactory enantioselectivities (ees) or distereoselectivities (des) Reviews the synthesis of a wide variety of interesting heterocycles by using a combination of different and versatile name reactions via MCRs

Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids

Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids
A Book

by Majid M. Heravi,Vahideh Zadsirjan

  • Publisher : Elsevier
  • Release : 2021-06-15
  • Pages : 350
  • ISBN : 9780128240212
  • Language : En, Es, Fr & De
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Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids includes comprehensive coverage of name reactions in the synthesis of alkaloids. This book highlights the synthesis of various alkaloids using special name reactions including the Diels-Alder, Friedel-Crafts, Heck, Mannich, Pauson-Khand, Pictet-Spengler, Sonogashira and Suzuki reactions. In this book, some selected name reactions in the total synthesis of alkaloids are covered, as they can be used as the key step/steps in the synthesis of different alkaloids exhibiting various biological activities. All chapters include an introduction, history and mechanism of the name reaction, and present the origin of the natural product and its known biological activities. The pathway to total synthesis is visually illustrated, and the focus is on the step in which a name reaction is applied. Chemists working in the area of synthetic organic chemistry will find this reference useful, as well as those working to develop novel methodologies for the synthesis of natural products in both academia and industry. This book is also beneficial to biologists, pharmacists and botanists. Includes an introduction of alkaloids, their origins and biological properties Features the applications of special name reactions as the key step in the total synthesis of featured alkaloids Covers the pathway for the synthesis of alkaloids from commercially available or easily accessible starting materials by using at least one name reaction to achieve the desired target products

Strategic Applications of Named Reactions in Organic Synthesis

Strategic Applications of Named Reactions in Organic Synthesis
A Book

by Laszlo Kurti,Barbara Czako

  • Publisher : Elsevier
  • Release : 2005-04-29
  • Pages : 864
  • ISBN : 0080575412
  • Language : En, Es, Fr & De
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Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings

Applied Organic Chemistry

Applied Organic Chemistry
Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry

by Surya K. De

  • Publisher : John Wiley & Sons
  • Release : 2021-01-26
  • Pages : 856
  • ISBN : 3527347852
  • Language : En, Es, Fr & De
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An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

I. The Design, Development and Application of New Reactions: Total Synthesis of (+)-aphanamol I and Transition Metal-catalyzed Multicomponent Reactions II. Synthesis of (-)-laulimalide and Analogues

I. The Design, Development and Application of New Reactions: Total Synthesis of (+)-aphanamol I and Transition Metal-catalyzed Multicomponent Reactions II. Synthesis of (-)-laulimalide and Analogues
A Book

by Lei Zhang

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 746
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pot, Atom, and Step Economy (PASE) Synthesis

Pot, Atom, and Step Economy (PASE) Synthesis
A Book

by Wei Zhang,Wen-Bin Yi

  • Publisher : Springer
  • Release : 2019-08-01
  • Pages : 49
  • ISBN : 3030225968
  • Language : En, Es, Fr & De
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This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the “twelve principles of green chemistry”, atom economy addresses ‘synthetic efficiency’. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis
A Book

by Jean Rodriguez,Damien Bonne

  • Publisher : John Wiley & Sons
  • Release : 2015-04-08
  • Pages : 480
  • ISBN : 1119006422
  • Language : En, Es, Fr & De
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Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions

Journal

Journal
A Book

by American Chemical Society

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Journal of Current Laser Abstracts

Journal of Current Laser Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1974
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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General Catalog

General Catalog
A Book

by Kansas State University

  • Publisher : Unknown Publisher
  • Release : 1970
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Energy Research Abstracts

Energy Research Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Scientific, Medical, and Technical Books Published in the United States of America

Scientific, Medical, and Technical Books Published in the United States of America
A Selected List of Titles in Print with Annotations : Second Supplement, Books Published 1949-1952

by Reginald Robert Hawkins

  • Publisher : Unknown Publisher
  • Release : 1953
  • Pages : 579
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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New Scientist

New Scientist
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Indian Science Abstracts

Indian Science Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009-05
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Physics Briefs

Physics Briefs
Physikalische Berichte

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Clay Minerals

Clay Minerals
Their Structure, Behaviour, and Use : Proceedings of a Royal Society Discussion Meeting Held on 9 and 10 November 1983

by Royal Society (Great Britain). Discussion Meeting,Royal Society (Great Britain)

  • Publisher : American Society of Civil Engineers
  • Release : 1984
  • Pages : 212
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Philosophical Transactions of the Royal Society of London

Philosophical Transactions of the Royal Society of London
Mathematical and physical sciences

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1984
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Generic Control for Batch Manufacturing

Generic Control for Batch Manufacturing
Advanced Control Techniques in Integrated Batch Control : Proceedings of the Sixteenth Annual Advanced Control Conference, West Lafayette, Indiana, September 24-26, 1990

by E. J. Kompass,Sharon K. Whitlock,Theodore Joseph Williams

  • Publisher : Purdue Univ
  • Release : 1990
  • Pages : 170
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Chemical Engineering Progress

Chemical Engineering Progress
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Microwaves in Organic Synthesis (Two Volume Set)

Microwaves in Organic Synthesis (Two Volume Set)
A Book

by André Loupy

  • Publisher : Wiley-VCH
  • Release : 2006-11-29
  • Pages : 1007
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The long awaited new edition of this comprehensive two-volume reference has been completely updated and expanded by 30% to include chapters on ionic liquids, carbohydrate chemistry, multicomponent reactions, solid phase peptide synthesis, carbon nanotubes and fullerenes. Written by the most eminent scientists in their respective fields, the chapters, which complement one another, now also include eight new fields of application, such as heterocyclic chemistry, cycloadditions and carbohydrate chemistry. In addition, very promising techniques under development are treated, resulting from the application of microwave irradiation to combinatorial chemistry, radiochemistry and photochemistry. The standard reference in this booming field. Andre Loupy received his PhD in 1975 from Paris-South University under Dr. Jacqueline Seyden-Penne at the Centre National de la Recherche Scientifique (CNRS) in Thiais, France. He joined the Laboratory of Selective Reactions on Supports in Paris-South University, Center of Orsay, before becoming the first class director of research at CNRS, where he led this lab until the end of 2005. He has some 280 publications and 10 chapters in several books to his name, and is a recipient of the M.J. Collins Award. Together with Georges Bram, Dr. Loupy has been concerned with microwave activation since 1987, especially when coupled to solvent-free conditions ("green chemistry") and the non-alimentary valorization of products from agriculture. His current research interests focus on medium effects in organic synthesis including solvent and salt effects, solvent-free conditions with a special interest in supported reactions and phase transfer catalysis.