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Recent Advances in Cancer Research and Therapy

Recent Advances in Cancer Research and Therapy
A Book

by Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi

  • Publisher : Elsevier
  • Release : 2012-05-18
  • Pages : 700
  • ISBN : 012397836X
  • Language : En, Es, Fr & De
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Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Recent Advances in Cancer Research and Therapy

Recent Advances in Cancer Research and Therapy
A Book

by Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi

  • Publisher : Elsevier
  • Release : 2012-06
  • Pages : 702
  • ISBN : 9780323282659
  • Language : En, Es, Fr & De
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Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. "Recent Advances in Cancer Research and Therapy" reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies.Formatted for a broad audience including all working in researching cancer treatments and therapies.Discusses special traits and results of Chinese cancer research.

Recent Advances in Cancer Treatment

Recent Advances in Cancer Treatment
A Book

by Henri J. Tagnon,Maurice J. Staquet

  • Publisher : Unknown Publisher
  • Release : 1977
  • Pages : 360
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Diagnostic and Therapeutic Advances in Pediatric Oncology

Diagnostic and Therapeutic Advances in Pediatric Oncology
A Book

by David O. Walterhouse,Susan L. Cohn

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 387
  • ISBN : 1461557674
  • Language : En, Es, Fr & De
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The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.

Recent Advances in Clinical Trial Design and Analysis

Recent Advances in Clinical Trial Design and Analysis
A Book

by Peter F. Thall

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 258
  • ISBN : 1461520096
  • Language : En, Es, Fr & De
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Clinical trials have two purposes -- to treat the patients in the trial, and to obtain information which increases our understanding of the disease and especially how patients respond to treatment. Statistical design provides a means to achieve both these aims, while statistical data analysis provides methods for extracting useful information from the trial data. Recent advances in statistical computing have enabled statisticians to implement very rapidly a broad array of methods which previously were either impractical or impossible. Biostatisticians are now able to provide much greater support to medical researchers working in both clinical and laboratory settings. As our collective toolkit of techniques for analyzing data has grown, it has become increasingly difficult for biostatisticians to keep up with all the developments in our own field. Recent Advances in Clinical Trial Design and Analysis brings together biostatisticians doing cutting-edge research and explains some of the more recent developments in biostatistics to clinicians and scientists who work in clinical trials.

Advances in Cancer Treatment

Advances in Cancer Treatment
From Systemic Chemotherapy to Targeted Therapy

by Iago Dillion Lima Cavalcanti,José Cleberson Santos Soares

  • Publisher : Springer
  • Release : 2021-03-30
  • Pages : 109
  • ISBN : 9783030683337
  • Language : En, Es, Fr & De
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This work covers the pathophysiology of cancer, exploring the difficulty of optimal treatment due to the complexity and diversity of cancer types. The search for distinctive molecular biology characteristics of tumor cells is especially relevant in the identification of overexpressed receptors and proteins that can be used as a target for cancer treatment. We highlight the main therapeutic modalities, particularly conventional systemic chemotherapy, addressing its mechanisms of action, therapeutic classes and even the toxic effects. We also describe the main tumor markers, their importance in the diagnosis and treatment of cancer, and the specificity of tumor cells. The first chapters serve as an introduction to the central topic of this book, targeted therapy. Key aspects of target therapy, such as classes of drugs, immunotherapy, monoclonal antibodies, checkpoint inhibitors, cancer vaccines and tyrosine kinase inhibitors are presented, and, for each one, the benefits, as well as the adverse effects are reported. Chapter 6 compares conventional systemic chemotherapy and targeted therapy, identifies the risks and benefits and also the eligibility criteria for patient care. The possibility of targeted therapy replacing conventional chemotherapy is discussed while reviewing studies that demonstrate the benefits of combining both types of treatment. Finally, the introduction of pharmaceutical nanotechnology to improve antineoplastic agents is addressed in the last chapter and sets the direction for future research in cancer treatment. This is a valuable resource for many health professionals including physicians, pharmacists, nurses, researchers and students interested in the field of oncology.

Proceedings of the First International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer

Proceedings of the First International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer
Cambridge, Massachusetts June 21-23, 2001

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 4443
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Cancer Research

Advances in Cancer Research
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2021-08-03
  • Pages : 426
  • ISBN : 0128241268
  • Language : En, Es, Fr & De
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Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Emerging Cancer Therapy

Emerging Cancer Therapy
Microbial Approaches and Biotechnological Tools

by Arsenio Fialho,Ananda Chakrabarty

  • Publisher : John Wiley & Sons
  • Release : 2010-12-07
  • Pages : 448
  • ISBN : 9781118035184
  • Language : En, Es, Fr & De
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Explores current and emerging applications of microbes as cancer-fighting agents WILEY SERIES IN BIOTECHNOLOGY AND BIOENGINEERING Anurag S. Rathore, Series Editor Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells. This book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancertargeting molecules. In addition, the book highlights the benefits of a multi-target approach to destroy cancer cells. Readers will not only discover the results and significance of basic and clinical research, but also encouraging results from clinical trials. Emerging Cancer Therapy is divided into three sections: Section 1: Live/Attenuated Bacteria and Viruses as Anticancer Agents Section 2: Bacterial Products as Anticancer Agents Section 3: Patents on Bacteria/Bacterial Products as Anticancer Agents With chapters written by leading pioneers in microbial, biotech, and cancer research, Emerging Cancer Therapy is recommended for biotechnologists, microbiologists, clinical oncologists, medicinal chemists, and biochemists. Readers will not only learn the tremendous potential of microbial and biotechnological approaches to cancer therapy, but also discover new directions of research for effective drug discovery and development.

Advances in Cancer Therapy

Advances in Cancer Therapy
A Book

by Hala Gali-Muhtasib

  • Publisher : IntechOpen
  • Release : 2011-11-21
  • Pages : 580
  • ISBN : 9789533077031
  • Language : En, Es, Fr & De
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The book "Advances in Cancer Therapy" is a new addition to the Intech collection of books and aims at providing scientists and clinicians with a comprehensive overview of the state of current knowledge and latest research findings in the area of cancer therapy. For this purpose research articles, clinical investigations and review papers that are thought to improve the readers' understanding of cancer therapy developments and/or to keep them up to date with the most recent advances in this field have been included in this book. With cancer being one of the most serious diseases of our times, I am confident that this book will meet the patients', physicians' and researchers' needs.

Autophagy and Senescence in Cancer Therapy

Autophagy and Senescence in Cancer Therapy
A Book

by Paul B. Fisher,David A. Gewirtz

  • Publisher : Elsevier
  • Release : 2021-04-29
  • Pages : 382
  • ISBN : 0128241586
  • Language : En, Es, Fr & De
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Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more. Addresses the relationship between autophagy and senescence in cancer therapy Covers autophagy and senescence in tumor dormancy Explores autophagy and senescence in disease recurrence

Current Immunotherapeutic Strategies in Cancer

Current Immunotherapeutic Strategies in Cancer
A Book

by Matthias Theobald

  • Publisher : Springer Nature
  • Release : 2019-08-31
  • Pages : 187
  • ISBN : 3030237656
  • Language : En, Es, Fr & De
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This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient’s cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment. Written by leading international experts and providing up-to-date information on emerging strategies, such as oncolytic virus-based therapy, epigenetic therapy, and combination therapy, the book appeals to all those with an interest in immunotherapy as it comes of age.

Preoperative (Neoadjuvant) Chemotherapy

Preoperative (Neoadjuvant) Chemotherapy
A Book

by Joseph Ragaz,Pierre R. Band,James H. Goldie

  • Publisher : Springer
  • Release : 1986-04-01
  • Pages : 162
  • ISBN : 9783540161295
  • Language : En, Es, Fr & De
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Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Lung Cancer

Lung Cancer
Treatment and Research

by Karen L. Reckamp

  • Publisher : Springer
  • Release : 2016-08-17
  • Pages : 322
  • ISBN : 3319403893
  • Language : En, Es, Fr & De
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This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

SURGICAL ONCOLOGY CURRENT CONCEPTS

SURGICAL ONCOLOGY CURRENT CONCEPTS
A Book

by C S McCardle

  • Publisher : CRC Press
  • Release : 1990-09-28
  • Pages : 332
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A wide range of topics in surgical oncology are covered, such as carcinoma of the oesophagus, breast cancer, tumours of the head and neck, principles of cancer therapy and recent advances in cancer research.

Advances in Radiation Therapy

Advances in Radiation Therapy
A Book

by Bharat B. Mittal,James A. Purdy,K.K. Ang

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 305
  • ISBN : 1461557690
  • Language : En, Es, Fr & De
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Recent advances in radiation oncology have depended upon and are intertwined with subsequent scientific discoveries and the development of new techniques in the fields of radiation and molecular biology, physics, electrical engineering, surgery, and medical oncology. This volume describes how some of the recent discoveries in the radiological sciences have influenced the way radiation oncology is practised. As there are many advances in this field, the Editors have chosen to concentrate on selected topics in clinical radiotherapy, radiation physics and biology, and technical innovations that have had a major impact on radiation oncology in the past twenty years. It is hoped that the techniques described in this volume will increase tumor control and prolong patient survival and at the same time decrease radiation-induced side effects and complications.

New Trends in the Molecular and Biological Basis for Clinical Oncology

New Trends in the Molecular and Biological Basis for Clinical Oncology
A Book

by Tetsuhiko Tachikawa,Nose Kiyoshi,Tohru Ohmori,Mitsuru Adachi

  • Publisher : Springer Science & Business Media
  • Release : 2009-04-05
  • Pages : 192
  • ISBN : 443188663X
  • Language : En, Es, Fr & De
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Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

Cancer

Cancer
Prevention, Early Detection, Treatment and Recovery

by Gary S. Stein,Kimberly P. Luebbers

  • Publisher : John Wiley & Sons
  • Release : 2019-10-01
  • Pages : 350
  • ISBN : 1118962885
  • Language : En, Es, Fr & De
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A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.

Angiogenesis Inhibition

Angiogenesis Inhibition
A Book

by Rüdiger Liersch,Wolfgang E. Berdel,Torsten Kessler

  • Publisher : Springer Science & Business Media
  • Release : 2009-12-24
  • Pages : 231
  • ISBN : 9783540782810
  • Language : En, Es, Fr & De
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Angiogenesis is attracting increased scientific and clinical interest. The identification of novel mediators and targeting molecules has led to significant progress in our understanding of tumor angiogenesis and tumor vessel targeting. Important advances in cancer treatment have already emerged, and in the future, blood vessel targeting will play a significant role within individualized therapeutic strategies. This volume provides a general overview of the latest developments in angiogenesis inhibition in cancer. All aspects from the bench to the bedside are considered, with detailed attention both to basic research and to its translation into clinical practice. Individual chapters are devoted to the roles of angiopoietins, HIF-1a, chemokines, PDGF and VEGF, and vascular integrins. The latest results of clinical trials are presented, and various advanced targeting strategies are discussed. This book will be invaluable to all who wish to learn of the most recent advances in this exciting field.

Proceedings of the First International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer

Proceedings of the First International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer
... Held June 21 - 23, 2001 in Cambridge Massachusetts

by International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer,Aman U. Buzdar

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 4442
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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