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Sarcopenia

Sarcopenia
Molecular, Cellular, and Nutritional Aspects

by Dominique Meynial-Denis

  • Publisher : CRC Press
  • Release : 2019-08-30
  • Pages : 352
  • ISBN : 0429531974
  • Language : En, Es, Fr & De
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Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.

Sarcopenia – Age-Related Muscle Wasting and Weakness

Sarcopenia – Age-Related Muscle Wasting and Weakness
Mechanisms and Treatments

by Gordon S. Lynch

  • Publisher : Springer Science & Business Media
  • Release : 2010-11-30
  • Pages : 479
  • ISBN : 9789048197132
  • Language : En, Es, Fr & De
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Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics. This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.

Sarcopenia

Sarcopenia
Molecular, Cellular, and Nutritional Aspects

by Dominique Meynial-Denis

  • Publisher : CRC Press
  • Release : 2019-11-20
  • Pages : 352
  • ISBN : 1498765149
  • Language : En, Es, Fr & De
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Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.

Reverse Sarcopenia

Reverse Sarcopenia
An Easy-to-Follow Program to Keep Muscles Strong and Youthful While Reducing Your Risk of Developing Dementia

by Joseph Tieri

  • Publisher : Simon and Schuster
  • Release : 2019-07-26
  • Pages : 128
  • ISBN : 1612439187
  • Language : En, Es, Fr & De
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Take control of your physical and brain health with low-level strength training We all know that we lose muscle mass as we age. But did you know that sarcopenic obesity (a.k.a. being “skinny fat”) is linked to increasing your risk of developing dementia and/or Alzheimer’s? Not only is losing muscle bad for your body, it’s also bad for your brain. Don’t let muscle deterioration negatively affect your future. It’s time to take your physical and brain health into your own hands with strength training. This book is full of tips, techniques, and easy-to-follow strength-training routines to fight sarcopenia. From beginners to those already comfortable using weights, this book has solutions for everyone. Lose fat, improve muscle tone, and strengthen bones while guarding against sarcopenia and its negative impact on your body and your brain. This book makes it easy to regain the muscle mass you need to live a healthier and longer life.

Frailty and Sarcopenia in Cirrhosis

Frailty and Sarcopenia in Cirrhosis
The Basics, the Challenges, and the Future

by Puneeta Tandon,Aldo J. Montano-Loza

  • Publisher : Springer Nature
  • Release : 2019-11-06
  • Pages : 279
  • ISBN : 303026226X
  • Language : En, Es, Fr & De
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This book provides a concise yet comprehensive overview of frailty and sarcopenia in the cirrhotic patient. The text presents a personalized approach to identifying cirrhotic patients at risk of higher morbidity and mortality due to frailty and sarcopenia. It reviews current and novel diagnostic methods, while spotlighting treatment and management strategies for frailty and sarcopenia. The book also focuses on special issues associated with these syndromes, such as the effect of gender, age, and ethnicity on frailty and sarcopenia, sarcopenic obesity, and frailty and sarcopenia after liver transplantation. Future considerations are outlined in the closing chapters, including emerging pharmacological and interventional therapies for these syndromes. Written by experts in the field, Frailty and Sarcopenia in Cirrhosis: The Basics, the Challenges, and the Future is a valuable resource for clinicians and practitioners who treat patients with cirrhosis.

Frailty and Sarcopenia

Frailty and Sarcopenia
Onset, Development and Clinical Challenges

by Yannis Dionyssiotis

  • Publisher : BoD – Books on Demand
  • Release : 2017-08-30
  • Pages : 254
  • ISBN : 9535134833
  • Language : En, Es, Fr & De
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Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

Sarcopenia

Sarcopenia
A Book

by Alfonso J. Cruz-Jentoft,John E. Morley

  • Publisher : John Wiley & Sons
  • Release : 2012-07-30
  • Pages : 364
  • ISBN : 1118338057
  • Language : En, Es, Fr & De
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Edited and written by world experts in the field, this book definesand explains the clinical relevance of an important geriatricsyndrome: Sarcopenia. The book covers all recent scientificevidence and treatment options including interventions to improvesarcopenia, nutritional approaches to treat sarcopenia and thefuture of drug treatments.

Body Composition and Aging

Body Composition and Aging
A Book

by C. V. Mobbs,Patrick R. Hof

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2010
  • Pages : 197
  • ISBN : 3805595212
  • Language : En, Es, Fr & De
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Increased adiposity and decreased muscle mass contribute substantially to age-dependent disease and disability. In particular age-related increase in adiposity is quickly becoming a major threat to public health throughout the world. Although the hypothesis that age-related changes in body composition are due to lifestyle choices alone is well accepted, it is a vast oversimplification. This volume reflects the current knowledge in this rapidly developing field of research. The first part of the book discusses the extent to which increased adiposity contributes to age-related diseases and longevity. The 'obesity paradox', describing the protective role of overweight in decreasing mortality while increasing pathology, is covered in depth. Further chapters address specific aspects of the regulation of energy balance during aging, including the effects of changes in food intake. Finally the causes and consequences of loss of muscle mass and age-related osteoporosis are examined. A valuable help for physicians treating elderly patients, this book will also be of great interest to researchers studying energy balance, muscle physiology, bone disease, and other aspects of aging.

Geriatric Nutrition

Geriatric Nutrition
A Book

by John E. Morley,David R. Thomas

  • Publisher : CRC Press
  • Release : 2007-05-30
  • Pages : 600
  • ISBN : 1420005499
  • Language : En, Es, Fr & De
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In a vicious cycle, poor nutritional health leads to acute and chronic disease, and disease states are catastrophic to nutritional health. The magnitude of nutritional depletion from any cause depends to a large extent on the nutritional reserves an individual has accumulated over time. In our increasingly older population, nutritional reserves are

Epidemiology of Sarcopenia and Frailty

Epidemiology of Sarcopenia and Frailty
A Book

by Harnish P Patel

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Sarcopenia and frailty are common in older persons and pose particular challenges for health and social care systems especially in the context of global population ageing. Sarcopenia, the loss of skeletal muscle mass, strength and function with age is associated with adverse individual physical and metabolic changes contributing to morbidity and mortality. The health and socioeconomic implications of sarcopenia are also considerable. Sarcopenia is a core component of physical frailty that together impact negatively on an individual's capability to live independently. Frailty is a biological syndrome of low reserve and resistance to stressors resulting from cumulative declines across multiple physiological systems that collectively predispose an individual to adverse outcomes. Frailty develops along a continuum from independence through to death as physiological reserves progressively diminish an individual's capacity to recover from an acute insult or illness. Managing sarcopenia and frailty involves the multidisciplinary led completion of a comprehensive care plan that is patient centred, responsive to the needs of the patient and adaptable therefore enabling an individual to maintain their independence.

Geriatric Physical Therapy - eBook

Geriatric Physical Therapy - eBook
A Book

by Andrew A. Guccione,Dale Avers,Rita Wong

  • Publisher : Elsevier Health Sciences
  • Release : 2011-03-07
  • Pages : 624
  • ISBN : 0323072410
  • Language : En, Es, Fr & De
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Geriatric Physical Therapy offers a comprehensive presentation of geriatric physical therapy science and practice. Thoroughly revised and updated, editors Andrew Guccione, Rita Wong, and Dale Avers and their contributors provide current information on aging-related changes in function, the impact of these changes on patient examination and evaluation, and intervention approaches that maximize optimal aging. Chapters emphasize evidence-based content that clinicians can use throughout the patient management process. Six new chapters include: Exercise Prescription, Older Adults and Their Families, Impaired Joint Mobility, Impaired Motor Control, Home-based Service Delivery, and Hospice and End of Life. Clinically accurate and relevant while at the same time exploring theory and rationale for evidence-based practice, it’s perfect for students and practicing clinicians. It’s also an excellent study aid for the Geriatric Physical Therapy Specialization exam. Comprehensive coverage provides all the foundational knowledge needed for effective management of geriatric disorders. Content is written and reviewed by leading experts in the field to ensure information is authoritative, comprehensive, current, and clinically accurate. A highly readable writing style and consistent organization make it easy to understand difficult concepts. Tables and boxes organize and summarize important information and highlight key points for quick reference. A well-referenced and scientific approach provides the depth to understand processes and procedures. Theory mixed with real case examples show how concepts apply to practice and help you enhance clinical decision-making skills. Standard APTA terminology familiarizes you with terms used in practice. A new chapter, Exercise Prescription, highlights evidence-based exercise prescription and the role of physical activity and exercise on the aging process. A new chapter, Older Adults and Their Families, helps physical therapists understand the role spouses/partners and adult children can play in rehabilitation, from providing emotional support to assisting with exercise programs and other daily living activities. New chapters on Impaired Joint Mobility, Impaired Motor Control, Home-based Service Delivery, and Hospice and End of Life expand coverage of established and emerging topics in physical therapy. Incorporates two conceptual models: the Guide to Physical Therapist Practice, 2nd Edition, and the International Classification of Function, Disability, and Health (ICF) of the World Health Organization (WHO) with an emphasis on enabling function and enhancing participation rather than concentrating on dysfunction and disability A companion Evolve website includes all references linked to MEDLINE as well as helpful links to other relevant websites.

Postmenopausal Osteoporosis: Basic and Clinical Concepts

Postmenopausal Osteoporosis: Basic and Clinical Concepts

by Meeta

  • Publisher : JAYPEE BROTHERS PUBLISHERS
  • Release : 2013-12-15
  • Pages : 281
  • ISBN : 9350908336
  • Language : En, Es, Fr & De
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Postmenopausal osteoporosis falls in the preview of the gynecologists, rheumatologists, endocrinologists, family physicians, orthopedicians, surgeons, pediatricians, physiotherapists, nutritionists and dentists too. Osteoporosis is the most common bone disorder affecting humans. It is a skeletal disorder characterized by compromised bone strength, predisposing a person to an increased risk of fracture. The outcomes in morbidity and mortality can be devastating. Galaxy of distinguished contributors from India and different parts of the globe contributed according to their expertise in this fiel.

Brocklehurst's Textbook of Geriatric Medicine and Gerontology E-Book

Brocklehurst's Textbook of Geriatric Medicine and Gerontology E-Book
A Book

by Howard M. Fillit,Kenneth Rockwood,Kenneth Woodhouse

  • Publisher : Elsevier Health Sciences
  • Release : 2010-05-10
  • Pages : 1152
  • ISBN : 1437720757
  • Language : En, Es, Fr & De
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Popular with generations of practitioners, Brocklehurst's Textbook of Geriatric Medicine and Gerontology has been the definitive reference of choice in the field of geriatric care. The new 7th Edition, by Howard M. Fillit, MD, Kenneth Rockwood, MD, and Kenneth Woodhouse, carries on this tradition with an increased clinical focus and updated coverage to help you meet the unique challenges posed by this growing patient population. Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy, while over 255 illustrations compliment the text to help you find what you need on a given condition. Examples of the latest imaging studies depict the effects of aging on the brain, and new algorithms further streamline decision making. Emphasizes the clinical relevance of the latest scientific findings to help you easily apply the material to everyday practice. Features consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more that make reference quick and easy. Includes over 255 illustrations—including algorithms, photographs, and tables—that compliment the text to help you find what you need on a given condition. Provides summary boxes at the end of each chapter that highlight important points. Features the work of an expert author team, now led by Dr. Howard M. Fillit who provides an American perspective to complement the book’s traditional wealth of British expertise. Includes an expanded use of algorithms to streamline decision making. Presents more color images in the section on aging skin, offering a real-life perspective of conditions for enhanced diagnostic accuracy. Includes examples of the latest imaging studies to help you detect and classify changes to the brain during aging. Offers Grade A evidence-based references keyed to the relevant text.

Sarcopenia, Obesity and Sarcopenic Obesity

Sarcopenia, Obesity and Sarcopenic Obesity
Effects on Liver Function and Volume in Patients Scheduled for Major Liver Resection

by Toine M. Lodewick,Anjali Anna Joy Röth,Steven W. M. Olde Damink,Patrick H. Alizai,Ronald M. van Dam,Nikolaus Gaßler,Mark Schneider,Simon A. W. G. Dello,Maximilian Schmeding,Cornelis H. C. Dejong,Ulf P. Neumann

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Professional Personal Trainer Certification Course

Professional Personal Trainer Certification Course
Basic Scientific Principles of Weight Resistant Training for Personal Trainers

by Joe Antouri

  • Publisher : AuthorHouse
  • Release : 2010-05
  • Pages : 328
  • ISBN : 1438987609
  • Language : En, Es, Fr & De
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Basic Scientific Principles of weight resistance training for private trainers. The Private Trainers Association course is a curriculum divided among practical application training and academic experience. Online or home course study is available when purchasing this book. The course is recognized and endorsed worldwide in 180 countries.

Clinical Nutrition and Aging

Clinical Nutrition and Aging
Sarcopenia and Muscle Metabolism

by Chad Cox

  • Publisher : CRC Press
  • Release : 2017-10-02
  • Pages : 306
  • ISBN : 1315359820
  • Language : En, Es, Fr & De
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This title includes a number of Open Access chapters. Sarcopenia—the loss of muscle mass and strength that occurs with advancing age—is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition

Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 1409
  • ISBN : 1464964580
  • Language : En, Es, Fr & De
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Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Disability, Rehabilitation, Wound Treatment, and Disease Management. The editors have built Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Disability, Rehabilitation, Wound Treatment, and Disease Management in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Muscular Atrophy Research and Treatment: 2012 Edition

Advances in Muscular Atrophy Research and Treatment: 2012 Edition
ScholarlyBrief

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-12-26
  • Pages : 43
  • ISBN : 1481616447
  • Language : En, Es, Fr & De
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Advances in Muscular Atrophy Research and Treatment / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Muscular Atrophy in a concise format. The editors have built Advances in Muscular Atrophy Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Muscular Atrophy in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Muscular Atrophy Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Rehabilitation in Sarcopenic Elderly

Rehabilitation in Sarcopenic Elderly
A Book

by Raoul Saggini

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Sarcopenia is a complex problem and an important emerging field in rehabilitation of the elderly. In 2010, the European working group on sarcopenia in older people (EWGSOP) described sarcopenia as a syndrome characterised by progressive and generalised loss of skeletal muscle mass and strength, associated with a risk of adverse outcomes such as physical disability, poor quality of life and death. This field of rehabilitation has been defined as 'evaluative, diagnostic and therapeutic interventions whose purpose is to restore functional ability or enhance residual functional capability in elderly people with disabling impairments'. With growing numbers of frail older people, there is an increasing need for appropriate geriatric rehabilitation services. Definitely, sarcopenia needs a specific rehabilitation program to improve muscular mass and strength that must be integrated with a global approach with the aim to recover postural assessment, amplify sensory-motor systems, in order to gain the necessary information for proper motor planning, to reduce risk of falls. Several physical agents in medicine permit to treat sarcopenia, like vibrations or electrical stimulation. The aim of this chapter is to give an overview about rehabilitative medicine for sarcopenia, highlighting the state of the art, presenting the most significative clinical researches and giving some inputs to set a rehabilitation protocol.

Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach

Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach

by Luciano Merlini,Paolo Bonaldo,Emanuele Marzetti

  • Publisher : Frontiers Media SA
  • Release : 2016-01-18
  • Pages : 329
  • ISBN : 2889196844
  • Language : En, Es, Fr & De
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Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.