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Separation Science and Proteomics

Separation Science and Proteomics
Current Trends and New Approaches

by Alexandre Stoyanov

  • Publisher : Academic Press
  • Release : 2017-06-01
  • Pages : 250
  • ISBN : 9780128032619
  • Language : En, Es, Fr & De
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Separation Science and Proteomics: Current Trends and New Approaches provides readers with the most advanced theories and methodologies on the most important separation methods contributing to current proteomics. Intended to be a practical reference that meets the needs of everyday practitioners, it also serves as a go-to guide for scientists focused on the theory of separation science, new methods development, and new equipment design. Future progress in proteomics is connected to the introduction of new and more powerful techniques and the perfection of techniques proposed over the past several decades, and an in-depth understanding of physical mechanisms for a particular separation method or methods combination is crucial for scientists who need to bridge the gap between traditional and contemporary methods. Authored by a chemist who has more than 20 years of experience in separation science and proteomics, this book offers readers insights and solutions to the separation mechanism of a full range of related techniques and complex problems, including the concentration distribution of analyzed protein during IEF separation in natural or IPG gradients or detailed mechanisms of electrophoresis in thermal gradients. Covers theoretical aspects, such as resolving power limitations as flow rate and electric current density reach technical limits Provides a critical review of newly proposed separation methods and approaches, including a range of equilibrium gradient methods Addresses the physical aspects important for optimization of the separation process, including acid–base equilibria, dissociation schemes, and chemistry of non-aqueous solutions Analyzes biophysical methods of protein structure analysis and discusses scaling to micro-separations and possible applications of nanotechnologies

Monolithic Silicas in Separation Science

Monolithic Silicas in Separation Science
Concepts, Syntheses, Characterization, Modeling and Applications

by Klaus K. Unger,Nobuo Tanaka,Egidijus Machtejevas

  • Publisher : John Wiley & Sons
  • Release : 2010-11-29
  • Pages : 362
  • ISBN : 352763326X
  • Language : En, Es, Fr & De
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Edited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals. Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.

Design and Synthesis of Advanced Materials for Separation Science

Design and Synthesis of Advanced Materials for Separation Science
A Book

by Michael Douglas Slater

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 380
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Separation Methods In Proteomics

Separation Methods In Proteomics
A Book

by Gary B. Smejkal,Alexander Lazarev

  • Publisher : CRC Press
  • Release : 2005-12-12
  • Pages : 536
  • ISBN : 1420028057
  • Language : En, Es, Fr & De
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Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems. Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis. Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated “subproteomes" for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, Separation Methods in Proteomics contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Introducing Proteomics

Introducing Proteomics
From Concepts to Sample Separation, Mass Spectrometry and Data Analysis

by Josip Lovric

  • Publisher : John Wiley & Sons
  • Release : 2011-06-17
  • Pages : 296
  • ISBN : 1119957192
  • Language : En, Es, Fr & De
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Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following: Separation Technologies Analysis of Peptides/Proteins by Mass Spectrometry Strategies in Proteomics This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student. This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems. "I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues." —Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin Companion Website www.wiley.com/go/lovric

Handbook of Pharmaceutical Biotechnology

Handbook of Pharmaceutical Biotechnology
A Book

by Shayne Cox Gad

  • Publisher : John Wiley & Sons
  • Release : 2007-05-25
  • Pages : 1680
  • ISBN : 9780470117101
  • Language : En, Es, Fr & De
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A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.

American Laboratory

American Laboratory
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Proteome Characterization and Proteomics

Proteome Characterization and Proteomics
A Book

by Timothy D. Veenstra,Richard D. Smith

  • Publisher : Academic Press
  • Release : 2003-10-01
  • Pages : 413
  • ISBN : 9780080569154
  • Language : En, Es, Fr & De
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The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics

Handbook of Isoelectric Focusing and Proteomics

Handbook of Isoelectric Focusing and Proteomics
A Book

by David Garfin,Satinder Ahuja

  • Publisher : Academic Press
  • Release : 2005-05-23
  • Pages : 334
  • ISBN : 9780120887521
  • Language : En, Es, Fr & De
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Isoelectric focusing (IEF) is a high-resolution, stand-alone technique that can be used as an analytical method or tool for protein purification. The only current book on the market, the Handbook of Isoelectric Focusing and Proteomics is the ideal 'one-stop' source for germane information in this discipline. This highly practical book also contains chapters on alternative methods that may pave the way in the search for efficient techniques for fractionating and purifying proteins. Complete with the history of IEF focusing to authors' insights and practical tips, this book is a must for anyone working in proteomics. * Is the only current book available on the subject * Includes author insights and practical tips * Is an ideal single source for students and researchers working in proteomics

Characterization and Improvement of Two-dimensional Gel Electrophoresis

Characterization and Improvement of Two-dimensional Gel Electrophoresis
A Book

by Christina M. Bondy

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 261
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Protein Protocols Handbook

The Protein Protocols Handbook
A Book

by John M. Walker

  • Publisher : Springer Protocols Handbooks
  • Release : 2009-10-07
  • Pages : 1991
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The third edition of The Protein Protocols Handbook introduces 57 critically important new chapters, and significantly updates the previous edition's tried-and-trusted methods. The book offers over 200 key, readily reproducible protocols that ensure results.

American Biotechnology Laboratory

American Biotechnology Laboratory
Buyer's guide edition

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A Century of Separation Science

A Century of Separation Science
A Book

by Haleem J. Issaq

  • Publisher : CRC Press
  • Release : 2001-12-19
  • Pages : 776
  • ISBN : 1482270927
  • Language : En, Es, Fr & De
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A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.

Proteomics: Biomedical and Pharmaceutical Applications

Proteomics: Biomedical and Pharmaceutical Applications
A Book

by Hubert Hondermarck

  • Publisher : Springer Science & Business Media
  • Release : 2007-05-08
  • Pages : 396
  • ISBN : 1402023235
  • Language : En, Es, Fr & De
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Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics. Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered.

Endocrinology

Endocrinology
A Book

by Leslie J. DeGroot

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 3633
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Revised throughout, the 5th Edition presents a complete and up-to-date review and analysis of all aspects of endocrinology, diabetes, and bone metabolism. Readers will also find state-of-the-art information on genetics, proteinomics, and hormone signaling, and coverage of the field{19}s hottest topics in nearly 20 new chapters. Joined by an international team of leading experts (many new to this edition) Drs. Jameson and DeGroot provide guidance that integrates the basic science of endocrinology with clinical medicine and the practical management of endocrine disorders with a clinical focus emphasizes diagnosis and therapy. It organizes information into basic and clinical sections that makes reference quick and easy, and provides tables designed to summarize and organize information, presenting over 1,400 illustrations that clarify complex concepts.

Genetic Engineering News

Genetic Engineering News
GEN.

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Proteomic Studies of Human Breast Cancer Cell Lines Using Multidimensional Separation Techniques and Time-of-flight Mass Spectrometry

Proteomic Studies of Human Breast Cancer Cell Lines Using Multidimensional Separation Techniques and Time-of-flight Mass Spectrometry
A Book

by Rick L. Hamler

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Understanding Stress Response in Desulfovibrio Vulgaris Hildenborough

Understanding Stress Response in Desulfovibrio Vulgaris Hildenborough
A Proteomics Approach

by Alyssa Marie Redding

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 582
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Liquid Chromatography

Liquid Chromatography
Applications

by Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola

  • Publisher : Elsevier
  • Release : 2017-06-23
  • Pages : 838
  • ISBN : 0128093447
  • Language : En, Es, Fr & De
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Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Wiley Encyclopedia of Chemical Biology, Volume 2

Wiley Encyclopedia of Chemical Biology, Volume 2
A Book

by Tadhg P. Begley

  • Publisher : Wiley-Blackwell
  • Release : 2009-02-03
  • Pages : 812
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.