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Stem Cell Therapy

Stem Cell Therapy
A Book

by Erik V. Greer

  • Publisher : Nova Publishers
  • Release : 2006
  • Pages : 234
  • ISBN : 9781594548482
  • Language : En, Es, Fr & De
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Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book brings together leading research from throughout the world in this frontier field.

Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
A Book

by Mohamed Al-Rubeai,Mariam Naciri

  • Publisher : Springer Science & Business Media
  • Release : 2013-10-01
  • Pages : 189
  • ISBN : 9400771967
  • Language : En, Es, Fr & De
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With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cell Therapy for Diabetes

Stem Cell Therapy for Diabetes
A Book

by Shimon Efrat

  • Publisher : Springer Science & Business Media
  • Release : 2009-12-01
  • Pages : 291
  • ISBN : 9781607613664
  • Language : En, Es, Fr & De
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Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Biomaterials for Stem Cell Therapy

Biomaterials for Stem Cell Therapy
State of Art and Vision for the Future

by Loredana De Bartolo,Augustinus Bader

  • Publisher : CRC Press
  • Release : 2013-01-28
  • Pages : 662
  • ISBN : 1466576405
  • Language : En, Es, Fr & De
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Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view. The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
A Book

by Lucas G. Chase,Mohan C Vemuri

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-12
  • Pages : 456
  • ISBN : 1627032002
  • Language : En, Es, Fr & De
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Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Handbook of Cardiac Stem Cell Therapy

Handbook of Cardiac Stem Cell Therapy
A Book

by Ioannis Dimarakis

  • Publisher : World Scientific
  • Release : 2009
  • Pages : 285
  • ISBN : 1848162561
  • Language : En, Es, Fr & De
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This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. So, beyond being excellent as an overall update for scientists in the field of cardiac stem cell therapy, this book will likely prove an indispensable tool for every budding scientist considering a research project within this field.

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair
From Basic Research to Clinical Applications

by Nabil Dib,Doris A. Taylor

  • Publisher : Springer Science & Business Media
  • Release : 2006
  • Pages : 335
  • ISBN : 9780387257884
  • Language : En, Es, Fr & De
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With insights from world authorities, including scientists and regulatory authorities, this book presents a review of stem cell therapy for the treatment of cardiovascular disease. The contributions in basic science, pre-clinical and clinical experience, assure a rapid course of translational research and clinical trials.

Stem Cell Therapy for Vascular Diseases

Stem Cell Therapy for Vascular Diseases
State of the Evidence and Clinical Applications

by Tulio Pinho Navarro,Lara Lellis Navarro Minchillo Lopes,Alan Dardik

  • Publisher : Springer Nature
  • Release : 2020-11-05
  • Pages : 425
  • ISBN : 3030569543
  • Language : En, Es, Fr & De
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Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.

Stem Cells

Stem Cells
Therapeutic Applications

by Mariusz Z. Ratajczak

  • Publisher : Springer Nature
  • Release : 2020-01-02
  • Pages : 406
  • ISBN : 3030312062
  • Language : En, Es, Fr & De
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Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.

Stem Cell Therapy for Autoimmune Disease

Stem Cell Therapy for Autoimmune Disease
A Book

by Richard K. Burt

  • Publisher : CRC Press
  • Release : 2019-11-11
  • Pages : 512
  • ISBN : 1000724670
  • Language : En, Es, Fr & De
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Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.

Regenerative Medicine and Cell Therapy

Regenerative Medicine and Cell Therapy
A Book

by Hossein Baharvand,Nasser Aghdami

  • Publisher : Springer Science & Business Media
  • Release : 2012-08-09
  • Pages : 318
  • ISBN : 1627030980
  • Language : En, Es, Fr & De
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Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Umbilical Cord Stem Cell Therapy

Umbilical Cord Stem Cell Therapy
The Gift of Healing from Healthy Newborns

by David A. Steenblock,Anthony G. Payne

  • Publisher : Basic Health Publications, Inc.
  • Release : 2006
  • Pages : 178
  • ISBN : 9781591201250
  • Language : En, Es, Fr & De
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Examines the potential for stem cells gleaned from umbilical cords to generate a wealth of new therapy and healing medicines for neurological conditions and blood problems.

The Stem Cell Cure

The Stem Cell Cure
Remake Your Body and Mind

by Gaurav K. Goswami, MD,Kerry Johnson MBA PhD

  • Publisher : Humanix Books
  • Release : 2020-03-31
  • Pages : 329
  • ISBN : 1630061190
  • Language : En, Es, Fr & De
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The 150+ year lifespan of our ancient ancestors can be achieved once again by harnessing the power of our own cells with The Stem Cell Cure! Renowned regenerative and restorative sports medicine doctor Gaurav Goswami, M.D. provides advanced minimally invasive, non-surgical treatments to help his patients get back to peak performance levels – no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of Stem Cell Therapy – the biggest revolution in medicine since the discovery of penicillin, and a wave of the future. Co-authored by bestselling author and popular keynote speaker Kerry Johnson MBA PhD, The Stem Cell Cure provides specific ways for readers to boost their health and vitality for a lifetime by recovering, regenerating, and repairing injuries and disease.

Advances in Stem Cell Research

Advances in Stem Cell Research
A Book

by Hossein Baharvand,Nasser Aghdami

  • Publisher : Springer Science & Business Media
  • Release : 2012-05-26
  • Pages : 398
  • ISBN : 1617799408
  • Language : En, Es, Fr & De
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Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Cardiovascular Regeneration and Stem Cell Therapy

Cardiovascular Regeneration and Stem Cell Therapy
A Book

by Annarosa Leri,Piero Anversa,William H. Frishman

  • Publisher : John Wiley & Sons
  • Release : 2008-04-15
  • Pages : 248
  • ISBN : 0470994304
  • Language : En, Es, Fr & De
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This book is the definitive reference on two of the most exciting areas of cardiovascular research – myocardial regeneration and stem cell therapy – for the treatment of disease. Edited by pioneers in the area, with contributions from every major investigator worldwide, it covers: The biology of stem cells The actions of stem cells from the bone marrow, the heart, and embryos on the normal restorative and repair functions of the heart and blood vessels How stem cells could contribute to myocardial recovery in the face of injury and aging How adjuvant therapy with growth factors might enhance stem cell activity in regeneration and repair Clinical applications and clinical experiences This fully referenced publication presents the current state of knowledge in both basic science and clinical practice, and is an essential reference for scientists, students, and clinicians.

How Adult Stem Cell Therapies Saved My Life

How Adult Stem Cell Therapies Saved My Life
Medicine's Best-kept Secret Can Save Your Life, Too

by Bernard Van Zyl

  • Publisher : AuthorHouse
  • Release : 2007
  • Pages : 154
  • ISBN : 1600080375
  • Language : En, Es, Fr & De
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In 2000, after receiving bypass surgery, an angioplasty, and entering a cardiac rehabilitation program, van Zyls heart was deteriorating. Turned down by two heart transplant centers, van Zyls only hope was in a new FDA-approved clinical trial for adult stem cell therapies. In this work, van Zyl offers information on the latest adult stem cell treatments for more than a dozen diseases and conditions.

Stem Cell-based Therapy for Neurodegenerative Diseases

Stem Cell-based Therapy for Neurodegenerative Diseases
A Book

by Fabin Han,Pengzhe (Paul) Lu

  • Publisher : Springer Nature
  • Release : 2020-10-26
  • Pages : 145
  • ISBN : 9811543704
  • Language : En, Es, Fr & De
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This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives

Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives
A Book

by Neil H. Riordan

  • Publisher : Neil H Riordan
  • Release : 2017-06-20
  • Pages : 302
  • ISBN : 9780999045305
  • Language : En, Es, Fr & De
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Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future.

Stem Cell Transplantation

Stem Cell Transplantation
A Book

by Carlos López-Larrea,Antonio López Vázquez,Beatriz Suárez Álvarez

  • Publisher : Springer Science & Business Media
  • Release : 2012-03-28
  • Pages : 342
  • ISBN : 1461420989
  • Language : En, Es, Fr & De
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Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

In Vitro Models for Stem Cell Therapy

In Vitro Models for Stem Cell Therapy
Methods and Protocols

by Peggy Stock,Bruno Christ

  • Publisher : Unknown Publisher
  • Release : 2021
  • Pages : 284
  • ISBN : 9781071612255
  • Language : En, Es, Fr & De
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This volume looks at in vitro disease models representing the respiratory, hepatobiliary, osteochondral, nervous, dermal, ocular, immune system, and pathological biological processes like tumorigenesis for stem cell research. The chapters in this book cover a range of diseases and application of various stem cells such as adult stem cells and iPS. Chapters also discuss new methods to characterize and manipulate stem cells with the aim to better understand and improve their biological performance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, In Vitro Models for Stem Cell Therapy: Methods and Protocols is a valuable resource for researchers and scientists interested in learning more about this exciting field.