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Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
A Book

by Mohamed Al-Rubeai,Mariam Naciri

  • Publisher : Springer Science & Business Media
  • Release : 2013-10-01
  • Pages : 189
  • ISBN : 9400771967
  • Language : En, Es, Fr & De
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With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cells: a Very Short Introduction

Stem Cells: a Very Short Introduction
A Book

by Jonathan Slack

  • Publisher : Oxford University Press
  • Release : 2021-09-23
  • Pages : 168
  • ISBN : 0198869290
  • Language : En, Es, Fr & De
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Stem cells are a rapidly developing area of research. This book explains the nature and different types of stem cells, explores their applications in medicine for treating diseases and injuries, and considers the major areas of current research.

Stem Cells in Development and Disease

Stem Cells in Development and Disease
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2014-01-15
  • Pages : 472
  • ISBN : 0123914353
  • Language : En, Es, Fr & De
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This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a comprehensive set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging Covers the area of Stem Cells in Development and Disease International board of authors Provides a comprehensive set of reviews covering such topics as Intestinal Stem Cells, Nephron Stem Cells/Progenitors, Skin epithelial Stem Cells and Lung Stem Cells

Stem Cells in Regenerative Medicine

Stem Cells in Regenerative Medicine
Science, Regulation and Business Strategies

by Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss

  • Publisher : John Wiley & Sons
  • Release : 2015-12-02
  • Pages : 776
  • ISBN : 111997139X
  • Language : En, Es, Fr & De
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This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.

Stem Cells

Stem Cells
A Short Course

by Rob Burgess

  • Publisher : John Wiley & Sons
  • Release : 2016-01-19
  • Pages : 384
  • ISBN : 1118439198
  • Language : En, Es, Fr & De
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The objective of this book is to provide a comprehensive learning tool for students in the rapidly evolving discpline of stem cell research. It thoroughly address all major facets and discplines related to stem cell biology and stem cell research, taking the reader first through its history, through a categorical description of all major cell types studied, advancements in research related to therapeutic applications, and finishing with a futuristic look at the impact of stem cells on mankind as well as worldwide government impact on stem cell research. The book is written at a level as to appeal to the student's interest in, and enthusiasm for, stem cells and their potential to significantly impact the field of medicine. By using the successful model of previously published "Short Courses", this text succeeds in conveying the key points without overburdening the reader with secondary information.

Stem Cells

Stem Cells
Therapeutic Applications

by Mariusz Z. Ratajczak

  • Publisher : Springer Nature
  • Release : 2020-01-02
  • Pages : 406
  • ISBN : 3030312062
  • Language : En, Es, Fr & De
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Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.

Advances in Application of Stem Cells: From Bench to Clinics

Advances in Application of Stem Cells: From Bench to Clinics
A Book

by Firdos Alam Khan

  • Publisher : Humana
  • Release : 2021-10-20
  • Pages : 316
  • ISBN : 9783030781002
  • Language : En, Es, Fr & De
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The field of stem cell biology is expanding with a continued surge of new information related to its applications. Over past few years, stem cells have been extensively used in cell therapy, tissue engineering, in vitro drug testing among others. At the moment there is no single book available which comprehensively describes the significance of various application of stem cells derived from embryonic and adult sources from lab to clinics. In this edited volume, we discuss basics and advanced topics of stem cells to help researchers, students and professional find the most important information in a single source of updated information about stem cells and relevant applications. This book is divided in 12 chapters and covers topics such as in vitro cell culture, 3D cell culture, cell therapy, tissue engineering, cell factory, cell functionality, in vitro drug testing, organ development, autologous transplantation, allogeneic transplantation, adult stem cells, multipotent stem cells, induced pluripotent stem cells, a pluripotent and embryonic stem cells.

Stem Cells

Stem Cells
From Biology to Therapy

by Robert A. Meyers

  • Publisher : John Wiley & Sons
  • Release : 2013-06-03
  • Pages : 778
  • ISBN : 3527668527
  • Language : En, Es, Fr & De
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This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields. This volume represents an essential guide for students and researchers seeking an overview of the field.

Stem Cells Biology and Therapeutics

Stem Cells Biology and Therapeutics
A Book

by Suchandra Chowdhury,Shyamasree Ghosh

  • Publisher : Springer
  • Release : 2021-06-17
  • Pages : 266
  • ISBN : 9789811616372
  • Language : En, Es, Fr & De
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Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences.

Stem Cells

Stem Cells
Controversy at the Frontiers of Science

by Elizabeth Finkel

  • Publisher : HarperCollins Australia
  • Release : 2012-07-01
  • Pages : 192
  • ISBN : 1743097913
  • Language : En, Es, Fr & De
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Stem Cells: Controversy at the Frontiers of Science provides a clear explanation of just what stem cells are - what the subtle differences are in the cells upon which most debate is focused - and why they are important for medical research. It explains how Australia found itself in the forefront of stem cell research, leading even the United States. But what is the story behind the headlines? Are stem cells the potential miracle cure-all that researchers would have us believe, solving problems from the search for donor organs to curing diseases such as Parkinsons and even cancer and dementia? And even if all the promises can be fulfilled, is it worth opening the potential Pandora's box of ethical problems? What is motivating the lobby groups for and against? Dr Elizabeth Finkel takes a clear-eyed look at the science, the ethics, the politics, the economics, the spin and the future.

Breast Cancer Stem Cells & Therapy Resistance

Breast Cancer Stem Cells & Therapy Resistance
A Book

by Phuc Van Pham

  • Publisher : Springer
  • Release : 2015-11-26
  • Pages : 114
  • ISBN : 3319220209
  • Language : En, Es, Fr & De
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This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters introduce and compare stem cells and cancer stem cells, describe properties and isolation techniques of BCSCs, and examine BCSC-targeting approaches. The text concludes with a discussion of controversy surrounding the BCSC hypothesis and of future research directions. Breast Cancer Stem Cells & Therapy Resistance, part of the SpringerBriefs in Stem Cells series, provides a succinct yet comprehensive overview of BCSCs for advanced students, graduate students and researchers as well as those working with breast cancer or stem cells in a clinical setting.

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside
A Book

by Kuldip S. Sidhu

  • Publisher : Bentham Science Publishers
  • Release : 2012
  • Pages : 237
  • ISBN : 1608052893
  • Language : En, Es, Fr & De
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"Pluripotent stem cells have garnered tremendous interest in recent years, which is primarily driven by the hope of finding a cure for several debilitating human diseases. Cell transplantation (regeneratve medicine) offers considerable therapeutic potentia"

Stem Cell Processing

Stem Cell Processing
A Book

by Phuc Van Pham

  • Publisher : Springer
  • Release : 2016-10-18
  • Pages : 225
  • ISBN : 3319400738
  • Language : En, Es, Fr & De
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This invaluable resource delineates procedures for development and use of stem cells in the laboratory and explores the potential for clinical applications. The text discusses mesenchymal stem cell isolation, isolation of adipose derived stem cells, new trends of induced pluripotent stem cells in disease treatment, cord blood banking, future directions of the discussed therapies and much more. The chapters are contributed by preeminent scientists in the field and present a comprehensive picture of stem cell processes, from development in the laboratory to effects and side-effects of clinical application. Stem Cell Processing and the other books in the Stem Cells in Clinical Applications series, edited by Dr. Phuc Van Pham, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Genetics of Stem Cells

Genetics of Stem Cells
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2012-12-31
  • Pages : 384
  • ISBN : 0124017460
  • Language : En, Es, Fr & De
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This special volume of Progress in Molecular Biology and Translational Science focuses on the genetics of stem cells. Contributions from leading authorities Informs and updates on all the latest developments in the field

Stem Cells

Stem Cells
Therapeutic Innovations under Control

by Nicole Arrighi

  • Publisher : Elsevier
  • Release : 2018-03-27
  • Pages : 192
  • ISBN : 0081025882
  • Language : En, Es, Fr & De
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Stem Cells: Therapeutic Innovations under Control traces the discovery of stem cells and induced pluripotent cells. It establishes the link between knowledge about cell development and tissue engineering, and presents perspectives in regenerative medicine. Cell proliferation and tissue architecture open up unexpected applications in tissue engineering, with the development of tissues or organs. In this context emerges the need to address the issue of bioethics and regulatory considerations. Because stem cells can multiply and differentiate into cells specific to a particular tissue or organ, they represent vast potential in the health field. Traces the discovery of stem cells to link knowledge of cell development with tissue engineering Presents prospects in regenerative medicine Establishes the link between knowledge about cell development and tissue engineering

Stem Cells and Tissue Engineering

Stem Cells and Tissue Engineering
A Book

by Mirjana Pavlovic,Bela Balint

  • Publisher : Springer Science & Business Media
  • Release : 2012-11-07
  • Pages : 154
  • ISBN : 1461455057
  • Language : En, Es, Fr & De
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Stem cells are the building blocks for all other cells in an organism. The human body has about 200 different types of cells and any of those cells can be produced by a stem cell. This fact emphasizes the significance of stem cells in transplantational medicine, regenerative therapy and bioengineering. Whether embryonic or adult, these cells can be used for the successful treatment of a wide range of diseases that were not treatable before, such as osteogenesis imperfecta in children, different forms of leukemias, acute myocardial infarction, some neural damages and diseases, etc. Bioengineering, e.g. successful manipulation of these cells with multipotential capacity of differentiation toward appropriate patterns and precise quantity, are the prerequisites for successful outcome and treatment. By combining in vivo and in vitro techniques, it is now possible to manage the wide spectrum of tissue damages and organ diseases. Although the stem-cell therapy is not a response to all the questions, it provides more and more answers every day. Stem Cells and Tissue Engineering is a concise review on the functional, phenotypic, regenerative, transplantational and curative aspects of a stem cell’s entity. It is critical and encouraging at the same time, providing truthful and appropriate samples from the practice and research that can lead toward optimal use of this immense source of adjuvant and curative therapy in human pathology. Written by a clinician and a researcher, who are currently teaching what they are doing, it is recommended as a teaching tool along with an original textbook.

Perinatal Stem Cells

Perinatal Stem Cells
A Book

by Anthony Atala,Sean V. Murphy

  • Publisher : Springer
  • Release : 2014-08-28
  • Pages : 373
  • ISBN : 149391118X
  • Language : En, Es, Fr & De
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This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology, and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, inflammatory disease, bone regeneration, pulmonary disease, and the treatment of spinal cord injury. Further, the book discusses current progress in the manufacturing, banking and clinical translation of perinatal stem cells. Through this book, readers will gain a thorough understanding of the current pre-clinical and clinical applications of perinatal stem cells as well as the efforts to support the transition of perinatal stem cell therapies from laboratories to clinics. Perinatal Stem Cells contains thirty-two chapters written by internationally recognized leaders in stem cell research. It is organized into four sections covering amniotic fluid stem cells, placental and placental membrane stem cells, umbilical cord stem cells, and clinical translation. This cohesive structure provides an effective framework for detailed insight into this new frontier. Edited by Dr. Anthony Atala, one of the foremost experts in the field, and his co-editor Dr. Sean V. Murphy, this volume is a definitive work for stem cell research and its future implications. It is a key resource for all stem cell researchers, clinicians, and government and industry staff working in this dynamic and exciting field.

Biology of Stem Cells and the Molecular Basis of the Stem State

Biology of Stem Cells and the Molecular Basis of the Stem State
A Book

by Dov Zipori

  • Publisher : Springer Science & Business Media
  • Release : 2009-09-01
  • Pages : 280
  • ISBN : 9781607611301
  • Language : En, Es, Fr & De
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Biology of Stem Cells and the Molecular Basis of the Stem State concentrates upon adult stem cells, particularly on mesenchymal cell populations, which is the author’s area of expertise. The text offers the reader a detailed description of the emergence of stem cell research and the dogmas that were created during the first decades of analysis of stem cell properties, particularly those of hemopoietic stem cells. Biology of Stem Cells and the Molecular Basis of the Stem State also introduces the reader to the commonly accepted notions regarding stem cell biology, with an emphasis on an alternative view of stemness, i.e. the stem state. In keeping with the popularity of this topic, Biology of Stem Cells and the Molecular Basis of the Stem State addresses the major controversies and points of dispute, among researchers in the stem cell field. Overall, Biology of Stem Cells and the Molecular Basis of the Stem State presents a well-rounded dialogue about stem cells as it not only concentrates upon the biological elements of stem cell, but also addresses the controversy and hype currently enveloping this popular subject.

Cancer Stem Cells

Cancer Stem Cells
A Book

by Lucie Laplane

  • Publisher : Harvard University Press
  • Release : 2016-06-06
  • Pages : 264
  • ISBN : 0674969561
  • Language : En, Es, Fr & De
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A new therapeutic strategy could break the stalemate in the war on cancer by targeting not all cancerous cells but the small fraction that lie at the root of cancers. Lucie Laplane offers a comprehensive analysis of cancer stem cell theory, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy.

Biomaterials as Stem Cell Niche

Biomaterials as Stem Cell Niche
A Book

by Krishnendu Roy

  • Publisher : Springer Science & Business Media
  • Release : 2010-09-30
  • Pages : 309
  • ISBN : 9783642138935
  • Language : En, Es, Fr & De
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Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.