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The Comorbidities of Epilepsy

The Comorbidities of Epilepsy
A Book

by Marco Mula

  • Publisher : Academic Press
  • Release : 2019-04-20
  • Pages : 413
  • ISBN : 0128148780
  • Language : En, Es, Fr & De
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Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

The Comorbidities of Epilepsy

The Comorbidities of Epilepsy
Concepts, Challenges, and Opportunities

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 134
  • ISBN : 9789463322799
  • Language : En, Es, Fr & De
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Cognitive and Psychiatric Comorbidities in Epilepsy: Insights from Neuroimaging Research

Cognitive and Psychiatric Comorbidities in Epilepsy: Insights from Neuroimaging Research
A Book

by Anja Haag,Clarissa Lin Yasuda,Britta Wandschneider,Silvia Bonelli

  • Publisher : Frontiers Media SA
  • Release : 2020-07-29
  • Pages : 129
  • ISBN : 2889638987
  • Language : En, Es, Fr & De
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Topic editor Dr Clarissa Lin Yasuda has received honoraria from UCB Pharma. All other topic editors declare no competing interests with regards to the Research Topic subject.

Comorbidities of Epilepsy

Comorbidities of Epilepsy
Special Topics

by Orrin Devinsky

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 48
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Improving Detection of Depression And/or Anxiety as Comorbidities of Epilepsy in Primary Health Care Settings in Zambia

Improving Detection of Depression And/or Anxiety as Comorbidities of Epilepsy in Primary Health Care Settings in Zambia
A Book

by Edward Kondwelani Mbewe

  • Publisher : Unknown Publisher
  • Release : 2013
  • Pages : 98
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Experimental & Clinical Epilepsy and Related Comorbidities

Experimental & Clinical Epilepsy and Related Comorbidities
A Book

by Mohd Farooq Shaikh,Teresa Ravizza,Jafri Malin Abdullah,Ayanabha Chakraborti,Terence John O’Brien

  • Publisher : Frontiers Media SA
  • Release : 2020-12-02
  • Pages : 129
  • ISBN : 2889661466
  • Language : En, Es, Fr & De
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Experimental Models of Epilepsy and Related Comorbidities

Experimental Models of Epilepsy and Related Comorbidities
A Book

by Mohd. Farooq Shaikh,Ayanabha Chakraborti,Annamaria Vezzani,Jafri Malin Abdullah

  • Publisher : Frontiers Media SA
  • Release : 2019-06-19
  • Pages : 129
  • ISBN : 2889458431
  • Language : En, Es, Fr & De
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Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.

Psychiatric Comorbidities and Quality of Life in Epilepsy

Psychiatric Comorbidities and Quality of Life in Epilepsy
A Book

by Ayşe Kutlu

  • Publisher : Unknown Publisher
  • Release : 2016
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Epilepsy is a chronic disorder characterized by a spontaneous tendency to recurrent seizures which affects patients' cognitive, behavioral, psychological, and social functioning. Epileptic patients face various problems that result in a lower quality of life. Seizure frequency, drug side effects, psychological comorbidity, and stigma are the major factors affecting the quality of lives of patients with epilepsy. Depression, anxiety, psychosis, and cognitive impairment are some of the comorbid psychiatric problems accompanying the clinical picture in epilepsy. Also the role of antiepileptic drugs (AEDs) in psychopathology of epilepsy should not be underestimated. One of the most important reasons why health-related quality of life (HRQOL) has become important for epileptic patients is related with well-known characteristics of this disorder. Its chronic nature, presence of unexpected, intractable and frequent seizures, and stigma are some of these characteristics among others. With the review of the current literature, it can be concluded that there is still a need for further scientific research to find out more clear relation between epilepsy, comorbidities, and HRQOL.

Epilepsy and the Interictal State

Epilepsy and the Interictal State
Co-morbidities and Quality of Life

by Erik K. St Louis,David M. Ficker,Terence J. O'Brien

  • Publisher : John Wiley & Sons
  • Release : 2015-03-16
  • Pages : 288
  • ISBN : 0470656239
  • Language : En, Es, Fr & De
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Epilepsy care traditionally focuses on seizures, yet for most epilepsy sufferers, other interictal factors such as mood, cognitive abilities, and treatment adverse effects most influence how they feel and function day to day. Epilepsy and the Interictal State is a practical and comprehensive text that covers quality of life issues, cognition and therapy, adverse effects of epilepsy treatments, mood state and psychiatric co-morbidity and general health aspects of epilepsy. Each chapter employs a standard structure providing background, epidemiology, pathophysiology, etiology, diagnosis, treatment, prognosis and further practical advice. From an international team of expert editors and contributors, Epilepsy and the Interictal State is a valuable resource for specialist epileptologists and neurologists, as well as for neurosurgeons, neurology nurses, psychiatrists, family physicians and general practitioners.

The Heart of Epilepsy

The Heart of Epilepsy
Cardiac Comorbidity and Sudden Death

by Sharon Shmuely

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 207
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The research described in this thesis aims to increase understanding of cardiac comorbidities and sudden unexpected death in epilepsy (SUDEP). People with epilepsy have a three-fold increased risk of dying prematurely compared to the general population. Common contributors to this are cardiovascular comorbidities, of which I provide an overview. Cardiovascular conditions and epilepsy can both lead to transient loss of consciousness (TLOC) with overlapping semiology. Particularly, myoclonic jerks which are commonly observed during syncope can be mistaken for signs of epilepsy. A misdiagnosis with detrimental consequences. I provide evidence that a careful analysis of motor phenomena can distinguish the two conditions. SUDEP is the commonest direct epilepsy-related premature death (UK >500 people/year). It typically occurs following convulsive seizures (CS). Most victims are found prone and some suggested people should sleep supine. I assessed video-EEG recordings of 180 CS and demonstrated peri-ictal positions often change, and most ending prone turned during CS. Sleeping supine is thus unlikely to prevent a postictal prone position and reduce risk of SUDEP. Pathomechanisms underlying SUDEP are likely a combination of interacting cardiorespiratory and autonomic factors. People with Dravet syndrome (DS) have a particular high SUDEP risk. I show that 49% of reported deaths in DS are SUDEP cases, most

The Epilepsy Book: A Companion for Patients

The Epilepsy Book: A Companion for Patients
Optimizing Diagnosis and Treatment

by Thalia Valeta

  • Publisher : Springer
  • Release : 2017-11-24
  • Pages : 208
  • ISBN : 331961679X
  • Language : En, Es, Fr & De
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This book presents scientific evidence about epilepsy along with straightforward guidance and recommendations. Responses to frequently asked questions and clarification of uncertainties are provided to empower patients to optimize their medical, psychological and social care. This book helps mediate between patients and health care professionals and can assist both sides to understand the condition of epilepsy at all levels. The information provided in the book empowers patients to share decision making with their carers and clinicians and enables them to make informed decisions, by taking into account the best scientific evidence, as well as the patients’ values and preferences. The Epilepsy Book: A Companion for Patients is ideal for patients with epilepsy and their carers, and will also be of interest to health care professionals, medical students and teachers. Thalia Valeta’s approach to epilepsy facilitates deeper understanding of the unmet needs and expectations of patients.

Headache and Comorbidities in Childhood and Adolescence

Headache and Comorbidities in Childhood and Adolescence
A Book

by Vincenzo Guidetti,Marco A. Arruda,Aynur Ozge

  • Publisher : Springer
  • Release : 2017-09-01
  • Pages : 242
  • ISBN : 3319547267
  • Language : En, Es, Fr & De
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This book aims to provide clinicians and other practitioners and professionals with up-to-date information on how to evaluate and manage headaches in children and adolescents, highlighting the most recent recommendations. Unlike in other books on the subject, detailed attention is devoted to the various comorbidities commonly associated with headache, including psychiatric comorbidities such as depression, anxiety, attention deficit hyperactivity disorder, and learning disabilities and medical conditions such as epilepsy, vascular disorders, brain tumors, atopic disease, and obesity. The intimate link between these conditions and headache is explained with a view to enabling the reader to recognize their presence and, on that basis, to institute the most effective pharmacological or non-pharmacological treatment strategy. Moreover, knowledge of the comorbidities associated with headache will help readers to understand more fully the causes of this serious disorder and also its consequences, e.g., for school performance, relationships, and daily activities. The authors are all international experts who care for children with headache or the other described disorders.

Challenges and Conundrums in Cannabinoid-Based Treatments for Epilepsy Syndromes and Associated Neurobehavioral Comorbidities

Challenges and Conundrums in Cannabinoid-Based Treatments for Epilepsy Syndromes and Associated Neurobehavioral Comorbidities
A Book

by Dolores E. López García,Ricardo Gómez-Nieto,Norberto Garcia-Cairasco

  • Publisher : Frontiers Media SA
  • Release : 2022-01-05
  • Pages : 129
  • ISBN : 2889719669
  • Language : En, Es, Fr & De
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Epilepsy Across the Spectrum

Epilepsy Across the Spectrum
Promoting Health and Understanding

by Institute of Medicine,Board on Health Sciences Policy,Committee on the Public Health Dimensions of the Epilepsies

  • Publisher : National Academies Press
  • Release : 2012-07-29
  • Pages : 568
  • ISBN : 0309259533
  • Language : En, Es, Fr & De
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Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Handbook on Epilepsy for Physicians

Handbook on Epilepsy for Physicians
A Book

by PV Rai,HV Srinivas,P Satishchandra,GT Subhas

  • Publisher : Jaypee Brothers Medical Publishers
  • Release : 2019-09-30
  • Pages : 198
  • ISBN : 9389188008
  • Language : En, Es, Fr & De
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Cognitive and Behavioral Comorbidities in Rolandic Epilepsy

Cognitive and Behavioral Comorbidities in Rolandic Epilepsy
A Book

by Chaabene mohamed

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Background and aims: Rolandic epilepsy (RE) is the most common form of benign childhood focal epilepsy This epilepsy is characterized by typical interictal-electroencephalogram (EEG) patterns mainly localized in centrotemporal and parietooccipital areas. The aims of our study were to describe of the clinical characteristics and outcomes of RE in our patients and evaluate behavioral and cognitive comorbidities. Method: We conducted a retrospective study of all cases of RE treated by our department from January 2010 to December 2017. The diagnosis was based on characteristic seizure manifestations and the typical EEG pattern of spikes or sharp waves in the centrotemporal area. The medical records of all participants were retrospectively reviewed for demographic information, past medical history, medication history, main seizure type, age of seizure onset, and number of anti-epileptic drugs (AEDs) currently prescribed. All patients were evaluated using behaviour and social abilities scale. Results: Thirty-four patients had their first seizure between the ages of 3 and 11 years. Most patients presented with simple partial seizures (66%), while 6 patients (21%) developed secondary generalized seizures. Twenty-two patients received anti-epileptic drugs to control recurrent seizures. The mean duration of follow-up was 6 years. Eight patients (28%) exhibited major behavioral problems at school and deficits in concentration. Three patients had intellectual disabilities.Conclusion: RE is a benign childhood epilepsy with generally favorable prognosis. However, a fraction of patients show learning disabilities and behavioral disturbances, particularly during the most active phase, and may require additional or continued therapy.

Epilepsy Simplified

Epilepsy Simplified
A Book

by John P Leach,,Rebecca O'Dwyer,

  • Publisher : tfm Publishing Limited
  • Release : 2011-01-01
  • Pages : 182
  • ISBN : 1908986603
  • Language : En, Es, Fr & De
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Simplicity is an underrated virtue; where information is vital, it should be possible to put it across in a way that is easy to understand and remember. Epilepsy is a common condition which has been recognised since the beginning of history, and as the opportunities for diagnosis and effective treatment have increased, it becomes more important that health professionals have a working knowledge of how epilepsy interacts with their own area of expertise. The interactions between all aspects of medicine and epilepsy should motivate all to do their best to learn about management of all stages of the disease, from first seizure through to status epilepticus. This is recognition that providing a diagnosis of epilepsy has more than medical implications, and in fact it is safe to say that there are few aspects of modern life that will remain untouched by such a diagnosis and consequent treatment. At some point, discussions will be required around the issues of fertility, job prospects, driving issues, family safety, childcare, travel, life insurance, diet, and sports participation. This book, has been produced by Dr Becky O'Dwyer and Dr John Paul Leach, recognised experts in epilepsy from opposite sides of the Atlantic. They have tried to make the key concepts of epilepsy's cause, prognosis and treatment accessible to all in this compact format, providing information for clinicians and permitting informed choice for patients and their families.

Psychiatric Comorbidity in Epilepsy

Psychiatric Comorbidity in Epilepsy
Basic Mechanisms, Diagnosis, and Treatment

by Harry McConnell

  • Publisher : American Psychiatric Pub
  • Release : 1998
  • Pages : 427
  • ISBN : 9780880488532
  • Language : En, Es, Fr & De
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Epilepsy affects 40 million people worldwide. With appropriate treatment most can become seizure free. For a minority of patients who also suffer from psychiatric comorbidity, however, diagnosis and management may be complicated by uncontrolled seizures, associated stigma or by the treatment of the epilepsy itself. Written by the world's foremost authorities on the neuropsychiatric manifestations of epilepsy, Psychiatric Comorbidity in Epilepsy is a comprehensive clinical, research, and treatment text for health care professionals -- including psychiatrists, neurologists, and neuropsychologists -- who treat patients with epilepsy and comorbid psychiatric problems. Based on a thorough knowledge of contemporary neuroscience, this book addresses the critical psychosocial and psychiatric issues that can affect patient care, including depression, psychosis, nonepileptic seizure-like events, antiepileptic drug toxicity, and family issues. This book also examines the possible links between the neurobiology of neuropsychiatric illness and the neurobiology of seizures, providing insight into brain behavior relations.

Neuroimaging of Epilepsy

Neuroimaging of Epilepsy
Disease Severity, Cognitive Comorbidities and Endophenotypes

by Lorenzo Caciagli

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
A Book

by Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé

  • Publisher : Academic Press
  • Release : 2017-06-14
  • Pages : 1178
  • ISBN : 012804067X
  • Language : En, Es, Fr & De
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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments