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The Paracellular Channel

The Paracellular Channel
Biology, Physiology, and Disease

by Jianghui Hou

  • Publisher : Academic Press
  • Release : 2018-06-08
  • Pages : 248
  • ISBN : 0128146362
  • Language : En, Es, Fr & De
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The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization. Offers integrated coverage of all key aspects of the paracellular channel, an understudied field that may hold key insights into some of the most mysterious aspects of physiology Targets different levels of expertise, spanning from graduate students, interns and clinical fellows, to seasoned researchers that study functions, regulation and dysfunctions of different tissue barriers Provides a cohesive and unifying picture that describes the critical functions of paracellular channels (tight junctions) in different tissues

Barriers and Channels Formed by Tight Junction Proteins I, Volume 1257

Barriers and Channels Formed by Tight Junction Proteins I, Volume 1257
A Book

by Michael Fromm,Jörg-Dieter Schulzke

  • Publisher : Wiley-Blackwell
  • Release : 2012-06-19
  • Pages : 252
  • ISBN : 9781573318730
  • Language : En, Es, Fr & De
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Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous system NOTE: Annals volumes are available for sale as individual books or as a journal. For informatio.n on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Barriers and Channels Formed by Tight Junction Proteins I

Barriers and Channels Formed by Tight Junction Proteins I
A Book

by Michael Fromm,Jörg-Dieter Schulzke

  • Publisher : Wiley-Blackwell
  • Release : 2012-06-19
  • Pages : 252
  • ISBN : 9781573318730
  • Language : En, Es, Fr & De
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Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous system NOTE: Annals volumes are available for sale as individual books or as a journal. For informatio.n on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Barriers and Channels Formed by Tight Junction Proteins

Barriers and Channels Formed by Tight Junction Proteins
I

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2012
  • Pages : 206
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous system"--Publisher description.

A Laboratory Guide to the Tight Junction

A Laboratory Guide to the Tight Junction
A Book

by Jianghui Hou

  • Publisher : Academic Press
  • Release : 2020-04-24
  • Pages : 420
  • ISBN : 0128226439
  • Language : En, Es, Fr & De
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A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases. Provides consistent and detailed research methods Covers various cell, tissue and animal models Includes step-by-step guidance from beginner to sophisticated levels

The Tight Junction and Its Proteins: More Than Just a Barrier

The Tight Junction and Its Proteins: More Than Just a Barrier
Volume 2

by Michael Fromm,Susanne M. Krug

  • Publisher : MDPI
  • Release : 2020-11-20
  • Pages : 432
  • ISBN : 3039433008
  • Language : En, Es, Fr & De
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For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ—mainly the two families of claudins and TAMPs—several other functions have been discovered, a striking one being the surprising finding that some claudins form paracellular channels for small ions and/or water. This Special Issue includes 43 articles covering numerous dedicated topics including pathogens affecting the TJ barrier, TJ regulation via immune cells, the TJ as a therapeutic target, TJ and cell polarity, function and regulation by proteins of the tricellular TJ, TJ as a regulator of cellular processes, organ- and tissue-specific functions, TJ as sensors and reacting to environmental conditions, and last but not least, TJ proteins and cancer.

Model for the Architecture of Claudin-Based Paracellular Ion Channels Through Tight Junctions

Model for the Architecture of Claudin-Based Paracellular Ion Channels Through Tight Junctions
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Tight Junction and Its Proteins: More Than Just a Barrier

The Tight Junction and Its Proteins: More Than Just a Barrier
A Book

by Michael Fromm,Susanne M. Krug

  • Publisher : MDPI
  • Release : 2020-11-20
  • Pages : 412
  • ISBN : 3039432249
  • Language : En, Es, Fr & De
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For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ—mainly the two families of claudins and TAMPs—several other functions have been discovered, a striking one being the surprising finding that some claudins form paracellular channels for small ions and/or water. This Special Issue includes 43 articles covering numerous dedicated topics including pathogens affecting the TJ barrier, TJ regulation via immune cells, the TJ as a therapeutic target, TJ and cell polarity, function and regulation by proteins of the tricellular TJ, TJ as a regulator of cellular processes, organ- and tissue-specific functions, TJ as sensors and reacting to environmental conditions, and last but not least, TJ proteins and cancer.

NC-1059, a Channel Forming Peptide, Induces a Reversible Change in Barrier Function of Epithelial Monolayers

NC-1059, a Channel Forming Peptide, Induces a Reversible Change in Barrier Function of Epithelial Monolayers
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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NC-1059 is a synthetic channel-forming peptide that provides for ion transport across, and transiently reduces barrier integrity of, cultured epithelial monolayers derived from canine kidney (MDCK cells; Broughman, J.R. et al; Am J Physiol Cell Physiol 286: C1312-23). In this first study experiments were conducted to determine whether epithelial cells derived from other sources were similarly affected. Human (T84, Calu-3) and non-human (IPEC-J2, PVD9902) epithelial cells derived from intestinal (T84, IPEC-J2), airway (Calu-3), and genitourinary (PVD9902) tissues were grown on permeable supports. Ion transport and barrier function were assessed electrically in a modified Ussing chamber. Basal short circuit current (I[subscript sc]) was typically less than 3 [Mu]A cm[superscript-2]. Apical NC-1059 exposure caused, in all cell types, an increase in I[subscript sc] to>15 [Mu]A cm[superscript-2], indicative of net anion secretion or cation absorption that was followed by an increase in transepithelial conductance (g[subscript te] in mS cm[superscript-2]; T-84, 1.6 to 62; PVD9902, 0.2 to 51; IPEC-J2, 0.3 to 26; Calu-3, 2.2 to 13). NC-1059 induces a concentration dependent change in the I[subscript sc] and g[subscript te] across these epithelia. The results in all cases were consistent with both a transcellular and a paracellular effect of the peptide. NC-1059 enhanced permeation of dextrans ranging from 10 kDa to 70 kDa across all epithelia tested. These results document an effect of NC-1059 on the paracellular route of epithelial barriers. Immunolabeling, confocal microscopy and immunoblotting methods were used in a second study to assess the molecular changes associated with increased paracellular permeability. NC-1059 induced a substantial reorganization of actin within 60 minutes of exposure. Confocal microscopy revealed that the changes in actin organization were accompanied by a pronounced change in the abundance and distribution of tight junction proteins occludin and ZO-1. Immunoblotting results suggest a time and concentration dependent effect on cellular abundance of these tight junction proteins. The effects on g[subscript te] and junctional proteins are transient with> 85% of recovery in 24 hours post exposure and full recovery within 48 hours. The reversible modulation of the epithelial tight junctions has therapeutic potential to increase the efficiency of drug delivery across barrier membranes.

The Tight Junction and Its Proteins

The Tight Junction and Its Proteins
More Than Just a Barrier

by Michael Fromm,Susanne M. Krug

  • Publisher : Unknown Publisher
  • Release : 2020
  • Pages : 432
  • ISBN : 9783039433018
  • Language : En, Es, Fr & De
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For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ--mainly the two families of claudins and TAMPs--several other functions have been discovered, a striking one being the surprising finding that some claudins form paracellular channels for small ions and/or water. This Special Issue includes 43 articles covering numerous dedicated topics including pathogens affecting the TJ barrier, TJ regulation via immune cells, the TJ as a therapeutic target, TJ and cell polarity, function and regulation by proteins of the tricellular TJ, TJ as a regulator of cellular processes, organ- and tissue-specific functions, TJ as sensors and reacting to environmental conditions, and last but not least, TJ proteins and cancer.

Introduction to Cellular Biophysics, Volume 2

Introduction to Cellular Biophysics, Volume 2
From Membrane Transport to Neural Signalling

by Armin Kargol

  • Publisher : Morgan & Claypool Publishers
  • Release : 2019-12-13
  • Pages : 106
  • ISBN : 1643277561
  • Language : En, Es, Fr & De
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All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Current Frontiers and Perspectives in Cell Biology

Current Frontiers and Perspectives in Cell Biology
A Book

by Stevo Najman

  • Publisher : BoD – Books on Demand
  • Release : 2012-04-25
  • Pages : 576
  • ISBN : 9535105442
  • Language : En, Es, Fr & De
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A numerous internationally renowned authors in the pages of this book present the views of the fields of cell biology and their own research results or review of current knowledge. Chapters are divided into five sections that are dedicated to cell structures and functions, genetic material, regulatory mechanisms, cellular biomedicine and new methods in cell biology. Multidisciplinary and often quite versatile approach by many authors have imposed restrictions of this classification, so it is certain that many chapters could belong to the other sections of this book. The current frontiers, on the manner in which they described in the book, can be a good inspiration to many readers for further improving, and perspectives which are highlighted can be seen in many areas of fundamental biology, biomedicine, biotechnology and other applications of knowledge of cell biology. The book will be very useful for beginners to gain insight into new area, as well as experts to find new facts and expanding horizons.

International Review of Cytology

International Review of Cytology
A Survey of Cell Biology

by Kwang W. Jeon

  • Publisher : Elsevier
  • Release : 2006-02-20
  • Pages : 320
  • ISBN : 9780080478623
  • Language : En, Es, Fr & De
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International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address new insights into fatty acid modulation of pancreatic beta cell function; drosophila RNA binding proteins; plasticity of pelvic autonomic ganglia and urogenital innervation; vomeronasal vs. olifactory epithelium: cellular basis for human vomeronasal perception; and tight junctions.

Cell-Cell Channels

Cell-Cell Channels
A Book

by František Baluška,Dieter Volkmann,Peter W. Barlow

  • Publisher : Springer Science & Business Media
  • Release : 2007-08-10
  • Pages : 321
  • ISBN : 0387469575
  • Language : En, Es, Fr & De
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he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.

Kidney Stones

Kidney Stones
Medical and Surgical Management

by Fredric Coe,Elaine M Worcester,James E Lingeman,Andrew P Evan

  • Publisher : Jaypee Brothers Medical Publishers
  • Release : 2019-09-30
  • Pages : 900
  • ISBN : 9351529428
  • Language : En, Es, Fr & De
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This book is the new edition of this comprehensive guide to the medical and surgical management of kidney stones. Divided into three main sections, the text begins with discussion on the basic formation of kidney stones, followed by mineral metabolism and diseases that lead to the formation of stones, with the final section describing surgical management techniques. The second edition has been thoroughly revised and expanded with new topics including imaging methods, non invasive surgical techniques, and management in special cases such as pregnancy. This new edition also includes discussion on stones in children. With an internationally recognised author team led by US-based specialists, this 900-page text is highly illustrated with clinical photographs and diagrams. Previous edition published in 1995. Key Points Comprehensive guide to medical and surgical management of kidney stones Fully revised second edition, with many new topics Highly illustrated with clinical photographs and diagrams over 900 pages Internationally recognised, US-based author team

Drug Delivery Systems

Drug Delivery Systems
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2019-10-23
  • Pages : 792
  • ISBN : 0128145080
  • Language : En, Es, Fr & De
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Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery systems within the pharmaceutical sciences industry and research, as well as in chemical engineering. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists. This book provides a comprehensive examination that is suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnologies, and related industries. Provides up-to-date information on how to translate the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as oral, parenteral, transdermal and inhalational Contains extensive references and further reading for course and self-study

Principles of Mucosal Immunology

Principles of Mucosal Immunology
A Book

by Phillip D. Smith,Richard S. Blumberg,Thomas T. MacDonald,Society for Mucosal Immunology

  • Publisher : Garland Science
  • Release : 2020-04-21
  • Pages : 596
  • ISBN : 1000754499
  • Language : En, Es, Fr & De
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This respected graduate-level textbook provides comprehensive and accessible coverage of the basic and clinical aspects of the mucosal immune system, addressing the major components of the mucosal barrier ̶ gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems ̶ in a highly user-friendly style. The editors of and contributors to the book, all internationally-recognized leaders, present the current principles, concepts, and basic processes involved in mucosal immunology, mucosal diseases, and host defense at mucosal surfaces. Topics discussed include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. The second edition has been carefully updated throughout to reflect the latest developments from clinical research and key literature has been fully updated.

Brenner and Rector's The Kidney E-Book

Brenner and Rector's The Kidney E-Book
A Book

by Alan S. L. Yu,Glenn M. Chertow,Valerie Luyckx,Philip A. Marsden,Karl Skorecki,Maarten W. Taal

  • Publisher : Elsevier Health Sciences
  • Release : 2015-10-25
  • Pages : 2784
  • ISBN : 0323262597
  • Language : En, Es, Fr & De
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Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification. Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations. Uniform terminology and nomenclature in line with emerging consensus in world kidney community. More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information. Internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors . An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields. The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.

The Pulmonary Epithelium in Health and Disease

The Pulmonary Epithelium in Health and Disease
A Book

by David Proud

  • Publisher : John Wiley & Sons
  • Release : 2008-04-30
  • Pages : 460
  • ISBN : 9780470727003
  • Language : En, Es, Fr & De
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"This is essential reading for everyone who would like to update their knowledge of the pulmonary epithelium. It offers a comparison between laboratory animal models and human lungs, highlighting the differences and the similarities between the two, which will be particularly useful to researchers." –Doody's, April 2009 The past two decades have seen extraordinary advances in our understanding of the role of the pulmonary epithelium in airway health and disease. Our understanding of epithelial biology has expanded exponentially in the past decade. This book provides a unique comprehensive description of the structure of the epithelium, its damage by various agents and the mechanism of epithelial repair. In addition, it's detailed coverage includes not only the multiple ways in which the epithelium contributes to host defence, but also the nature and functional consequences of the interactions of inhaled pathogens, including viruses, bacteria, allergens and pollutants. the role of the epithelium in regulating airway inflammation and structure is also discussed, as is the role of the epithelium as a target for inhaled medications and as a route for novel drug delivery. Containing chapters on multiple aspects of epithelial function in health and disease, each one is written by a leader in the field. This is essential reading for pulmonary researchers and physicians requiring detailed advanced understanding of the epithelium as well as those working in allergy, biomedical and pharmaceutical research.

International Review of Cytology

International Review of Cytology
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 1988-07-01
  • Pages : 259
  • ISBN : 9780080586496
  • Language : En, Es, Fr & De
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International Review of Cytology