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The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health

The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health
A Book

by Rodney A. Samaan,Christopher Samaan

  • Publisher : Academic Press
  • Release : 2021-08-16
  • Pages : 308
  • ISBN : 9780128174326
  • Language : En, Es, Fr & De
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The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health is a comprehensive investigation into the cardiovascular health effects of marijuana use. As the prevalence of cannabis use increases both recreationally and clinically, a shroud of misinformation exists in academia, the public, and clinical realms. Further, since different studies show contradictory results it is hard to determine the exact benefits for cannabis use. This book will focus on a specific set of cardiovascular diseases plaguing the current population and the effects of cannabis will be addressed from numerous viewpoints including human physiological and clinical disease outcomes to issues in public health. By gathering this information in a way that addresses numerous viewpoints the book serves as a comprehensive reference and clinical guide Compiles the numerous contradictory reports about the effects of marijuana and cardiovascular disease for ease in comparison Examines the mechanisms that have shown how marijuana use might contribute to the development of chronic cardiovascular conditions and/or acutely trigger cardiovascular events Includes coverage of the drug's role in pharmacotherapy

The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
The Current State of Evidence and Recommendations for Research

by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda

  • Publisher : National Academies Press
  • Release : 2017-05-01
  • Pages : 486
  • ISBN : 0309453046
  • Language : En, Es, Fr & De
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Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Principles of Addiction Medicine

Principles of Addiction Medicine
A Book

by Richard K. Ries,Shannon C. Miller,David A. Fiellin

  • Publisher : Lippincott Williams & Wilkins
  • Release : 2009
  • Pages : 1570
  • ISBN : 9780781774772
  • Language : En, Es, Fr & De
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This respected text from the American Society of Addiction Medicine is valuable for all physicians and mental-health personnel who specialize in addiction medicine and who treat patients with addiction disorders. The chapters blend scientific principles underlying addiction with the practical essentials of clinical addiction medicine. Many of the contributors are affiliated with leading government agencies that study addiction and its science, such as the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse. The book will appeal to a wide and interdisciplinary range of professionals, especially those with interest or duties relating to addiction-related disorders, and in particular physicians seeking certification status via either the American Board of Addiction Medicine or the American Board of Psychiatry and Neurology. A companion Website will offer the fully searchable text.

CBD Oil for Psychosis & Schizophrenia

CBD Oil for Psychosis & Schizophrenia
The Ultimate Guide On Everything About Psychosis & Schizophrenia. How It Can Be Treated with CBD Oil

by Eric Hilton

  • Publisher : Unknown Publisher
  • Release : 2019-06-19
  • Pages : 86
  • ISBN : 9781075005800
  • Language : En, Es, Fr & De
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We mentioned that psychosis and schizophrenia are mental disorders that represent a total detachment from reality, but what is it that actually causes this to happen? What takes place in the brain that drives an individual to become separated from the real world?In short, scientists are not sure what exactly causes the onset of psychosis or schizophrenia. Regardless of what you may have heard in the past, they are unsure of why some people develop psychotic symptoms over the course of their life, and others do not. Unlike medical conditions like diabetes or heart disease, no one has been unable to pinpoint an exact physiological condition which accounts for the disorder.The endocannabinoid system (ECS) in the brain plays an important role in maintaining normal mental health. ECS modulates emotion, reward processing, sleep regulation, aversive memory extinction and HPA axis regulation.. The cannabis plant synthesises a large number of pharmacologically active compounds unique to it known as phytocannabinoids. In contrast to the euphoric and pro-psychotic effects of delta-9-tetrahydrocannabinol (THC), certain non-intoxicating phytocannabinoids have emerged in pre-clinical and clinical models as potential APs. Since the likely mechanism of action does not rely upon dopamine D2 receptor antagonism, synergistic combinations with existing APs are plausible. The anti-inflammatory and immunomodulatory effects of the non-intoxicating phytocannabinoid cannabidiol (CBD) are well established. Preliminary data reviewed in a paper suggest that CBD in combination with a CB1 receptor neutral antagonist could not only augment the effects of standard APs but also target the metabolic, inflammatory and stress-related components of the schizophrenia phenotype.The medical properties of cannabis have been known for many centuries; its first documented use dates back to 2800 BC when it was described for its hallucinogenic and pain-relieving properties. In the first half of the twentieth century, a number of pharmaceutical companies marked cannabis for indications such as asthma and pain, but since then its use has sharply declined, mainly due to its unpredictable effects, but also for socio-political issues. Recently, great attention has been directed to the medical properties of phytocannabinoids present in the cannabis plant alongside the main constituent Δ⁹-Tetrahydrocannabinol (THC); these include cannabinoids such as cannabidiol (CBD), cannabigerol (CBG), and tetrahydrocannabivarin (THCV). Evidence suggests an association between cannabis and schizophrenia: schizophrenics show a higher use of marijuana as compared to the healthy population. Additionally, the use of marijuana can trigger psychotic episodes in schizophrenic patients, and this has been ascribed to THC. Given the need to reduce the side effects of marketed antipsychotics, and their weak efficacy on some schizophrenic symptoms, cannabinoids have been suggested as a possible alternative treatment for schizophrenia. CBD (cannabidiol), a non-psychoactive constituent of Cannabis.Cannabis sativa plant, has been receiving growing attention for its anti-psychotic-like properties. Evidence suggests that its non-psychoactive component, i.e CBD can ameliorate positive and negative symptoms of schizophrenia. Behavioural and neurochemical models suggest that CBD has a pharmacological profile similar to that of atypical anti-psychotic drugs and a clinical trial reported that this cannabinoid is a well-tolerated alternative treatment for schizophrenia. This book gives an account on everything about CBD Oil, psychosis & schizophrenia, and how CBD can help to cure it.

Cannabis, Health Risks

Cannabis, Health Risks
A Comprehensive Annotated Bibliography, (1844-1982)

by Oriana Josseau Kalant,Addiction Research Foundation of Ontario

  • Publisher : Unknown Publisher
  • Release : 1983
  • Pages : 1100
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cannabinoids in Health and Disease

Cannabinoids in Health and Disease
A Book

by Rosaria Meccariello,Rosanna Chianese

  • Publisher : BoD – Books on Demand
  • Release : 2016-06-15
  • Pages : 258
  • ISBN : 9535124293
  • Language : En, Es, Fr & De
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This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.

Oxford Textbook of Pediatric Pain

Oxford Textbook of Pediatric Pain
A Book

by Bonnie J. Stevens,Gareth Hathway,William T. Zempsky

  • Publisher : Oxford University Press
  • Release : 2021-06-25
  • Pages : 704
  • ISBN : 0192550799
  • Language : En, Es, Fr & De
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Our understanding of how pain in early life differs to that in maturity is continuing to increase and develop, using a combination of approaches from basic science, clinical science, and implementation science. The new edition of the Oxford Textbook of Pediatric Pain brings together an international team of experts to provide an authoritative and comprehensive textbook on all aspects of pain in infants, children, and youth. Divided into nine sections, the textbook analyses pain as a multifactorial problem to give the reader a comprehensive understanding of this challenging subject. Evidence-based chapters look in depth at topics ranging from the long-term effects of pain in children, to complementary therapy in paediatric pain. The text addresses the knowledge-to-practice gap through individual and organizational implementation, and facilitation strategies. Case examples and perspective boxes are provided to aid learning and illustrate the application of knowledge. Written by clinicians, educators, trainees, and researchers, hand selected by the Editors for their practical approach and expertise in specific subject areas, the new edition of the Oxford Textbook of Pediatric Pain is an essential reference text in the assessment and treatment of patients and families in the field of paediatric pain. Purchasers of the print version of the second edition will have free access on Oxford Medicine Online to all the content for the life of the edition.

CBD Oil for Psychosis & Schizophrenia

CBD Oil for Psychosis & Schizophrenia
The Ultimate Guide On Everything About Psychosis & Schizophrenia. How It Can Be Treated with CBD Oil

by Gregg Hansen

  • Publisher : Independently Published
  • Release : 2019-08-26
  • Pages : 82
  • ISBN : 9781688762008
  • Language : En, Es, Fr & De
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We mentioned that psychosis and schizophrenia are mental disorders that represent a total detachment from reality, but what is it that actually causes this to happen? What takes place in the brain that drives an individual to become separated from the real world? In short, scientists are not sure what exactly causes the onset of psychosis or schizophrenia. Regardless of what you may have heard in the past, they are unsure of why some people develop psychotic symptoms over the course of their life, and others do not. Unlike medical conditions like diabetes or heart disease, no one has been unable to pinpoint an exact physiological condition which accounts for the disorder. The endocannabinoid system (ECS) in the brain plays an important role in maintaining normal mental health. ECS modulates emotion, reward processing, sleep regulation, aversive memory extinction and HPA axis regulation.. The cannabis plant synthesises a large number of pharmacologically active compounds unique to it known as phytocannabinoids. In contrast to the euphoric and pro-psychotic effects of delta-9-tetrahydrocannabinol (THC), certain non-intoxicating phytocannabinoids have emerged in pre-clinical and clinical models as potential APs. Since the likely mechanism of action does not rely upon dopamine D2 receptor antagonism, synergistic combinations with existing APs are plausible. The anti-inflammatory and immunomodulatory effects of the non-intoxicating phytocannabinoid cannabidiol (CBD) are well established. Preliminary data reviewed in a paper suggest that CBD in combination with a CB1 receptor neutral antagonist could not only augment the effects of standard APs but also target the metabolic, inflammatory and stress-related components of the schizophrenia phenotype.The medical properties of cannabis have been known for many centuries; its first documented use dates back to 2800 BC when it was described for its hallucinogenic and pain-relieving properties. In the first half of the twentieth century, a number of pharmaceutical companies marked cannabis for indications such as asthma and pain, but since then its use has sharply declined, mainly due to its unpredictable effects, but also for socio-political issues. Recently, great attention has been directed to the medical properties of phytocannabinoids present in the cannabis plant alongside the main constituent Δ⁹-Tetrahydrocannabinol (THC); these include cannabinoids such as cannabidiol (CBD), cannabigerol (CBG), and tetrahydrocannabivarin (THCV). Evidence suggests an association between cannabis and schizophrenia: schizophrenics show a higher use of marijuana as compared to the healthy population. Additionally, the use of marijuana can trigger psychotic episodes in schizophrenic patients, and this has been ascribed to THC. Given the need to reduce the side effects of marketed antipsychotics, and their weak efficacy on some schizophrenic symptoms, cannabinoids have been suggested as a possible alternative treatment for schizophrenia. CBD (cannabidiol), a non-psychoactive constituent of Cannabis.Cannabis sativa plant, has been receiving growing attention for its anti-psychotic-like properties. Evidence suggests that its non-psychoactive component, i.e CBD can ameliorate positive and negative symptoms of schizophrenia. Behavioural and neurochemical models suggest that CBD has a pharmacological profile similar to that of atypical anti-psychotic drugs and a clinical trial reported that this cannabinoid is a well-tolerated alternative treatment for schizophrenia. This book gives an account on everything about CBD Oil, psychosis & schizophrenia, and how CBD can help to cure it.

Health and Educational Effects of Marijuana on Youth

Health and Educational Effects of Marijuana on Youth
Hearing Before the Subcommittee on Alcoholism and Drug Abuse of the Committee on Labor and Human Resources, United States Senate, Ninety-seventh Congress, First Session on Examination of the Health and Educational Effects of Marijuana Or Youth, October 21, 1981

by United States. Congress. Senate. Committee on Labor and Human Resources. Subcommittee on Alcoholism and Drug Abuse

  • Publisher : Unknown Publisher
  • Release : 1982
  • Pages : 132
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cannabis in Medical Practice

Cannabis in Medical Practice
A Legal, Historical and Pharmacological Overview of the Therapeutic Use of Marijuana

by Mary Lynn Mathre, R.N.

  • Publisher : McFarland
  • Release : 2012-11-12
  • Pages : 247
  • ISBN : 0786483903
  • Language : En, Es, Fr & De
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Because marijuana is a Schedule I drug under the Controlled Substances Act, the therapeutic benefits of cannabis are no longer mentioned in the formal education of health care professionals. Doctors who do learn of the drug’s therapeutic value are often intimidated by its illegal status. Thus millions of patients afflicted with such illnesses as glaucoma, AIDS, cancer, multiple sclerosis, spinal cord injuries, seizure disorders and chronic pain are denied access to information about the drug’s benefits and, in many cases, suffer needlessly. Straightforward and nonpoliticized information on the therapeutic uses of cannabis is provided here by medical, legal and scientific professionals. Legal issues, a worldwide history of therapeutic cannabis and a discussion of its pharmacology are covered. Specific medical uses are then examined, including its application for sufferers of cancer, AIDS, glaucoma, and seizure disorders, and its potential use in psychiatry. Dosages and administration of cannabis are explored, along with considerations on the use of the drug during pregnancy and the risks of addiction and dependency.

Marijuana and the Cannabinoids

Marijuana and the Cannabinoids
A Book

by Mahmoud A. ElSohly

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-15
  • Pages : 322
  • ISBN : 1592599478
  • Language : En, Es, Fr & De
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Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC in 1964. The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.

Cannabis Extracts in Medicine

Cannabis Extracts in Medicine
The Promise of Benefits in Seizure Disorders, Cancer and Other Conditions

by Jeffrey Dach, M.D.,,Elaine A. Moore,Justin Kander

  • Publisher : McFarland
  • Release : 2015-10-16
  • Pages : 220
  • ISBN : 0786496630
  • Language : En, Es, Fr & De
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“Policy makers in states considering legalizing marijuana for medical purposes should read this well-researched book...recommended“—Choice “For students, academics, researchers, medical professionals and general interest readers...presents an examination of the potential medicinal uses of cannabis extracts.“—Reference & Research Book News As of December 2014, medicinal cannabis is legal in 23 states where news and medical journals report success stories of people recovering from diverse medical conditions such as epilepsy, cancer and chronic pain. In states where cannabis remains illegal, users and providers risk arrest and imprisonment. While the United States government has restricted cannabis medical research, advances have been made in Israel, Spain and Italy. One such breakthrough was the discovery of the endocannabinoid system in the brain and immune system. Endogenous cannabinoids are mimicked by THC and cannabidiol (CBD), cannabinoids found in the cannabis plant, thus accounting for its medicinal effects. Focusing on the biochemical properties, medical benefits and psychological effects of cannabinoids, this book provides an overview of anecdotal case reports, animal studies and clinical trials proposing cannabis for seizure disorder, cancer, chronic pain and other medical conditions.

Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health

Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health
A Book

by George E. Barreto

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030648729
  • Language : En, Es, Fr & De
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A Psychiatrist's View of Marijuana

A Psychiatrist's View of Marijuana
A Book

by Timmen Cermak

  • Publisher : Cambridge University Press
  • Release : 2020-02-29
  • Pages : 150
  • ISBN : 1108735738
  • Language : En, Es, Fr & De
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An essential guide covering the scientific knowledge and communication skills required to deliver objective patient advice about marijuana use.

New Trends of Substance Abuse: Looking for New Psychotropic Effects of Chem Sex Drugs, Cognitive Enhancers, and New Psychoactive Substances

New Trends of Substance Abuse: Looking for New Psychotropic Effects of Chem Sex Drugs, Cognitive Enhancers, and New Psychoactive Substances
A Book

by Simona Zaami,Simona Pichini,Marta Torrens,Norbert Leo Scherbaum

  • Publisher : Frontiers Media SA
  • Release : 2021-01-08
  • Pages : 329
  • ISBN : 2889663663
  • Language : En, Es, Fr & De
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Cannabinoid Pharmacology

Cannabinoid Pharmacology
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2017-08-18
  • Pages : 492
  • ISBN : 0128112336
  • Language : En, Es, Fr & De
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Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered. Presents reviews of recent breakthroughs in the cannabinoid system Features chapters from the best authors in the field Provides an essential resource for scientists, advanced undergraduate students through to established faculty members

Cannabinoid Therapeutics: What's Hot

Cannabinoid Therapeutics: What's Hot
A Book

by Fabricio A. Pamplona,Carsten T. Wotjak,Mark Ware

  • Publisher : Frontiers Media SA
  • Release : 2020-02-07
  • Pages : 277
  • ISBN : 2889634191
  • Language : En, Es, Fr & De
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Every year, 10 outstanding Research Topics are selected as finalists of the Frontiers Spotlight Award. These shortlisted article collections each address a globally important field of research with the potential to drastically impact our future. They bring together the latest, cutting-edge research to advance their fields, present new solutions and foster essential, large-scale collaborations across multiple disciplines and research groups worldwide. This international research prize recognizes the most innovative and impactful topics and the winning team of editors receives $100,000 to organize an international scientific conference on the theme of their successful collection.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog
Cumulative listing

by National Library of Medicine (U.S.)

  • Publisher : Unknown Publisher
  • Release : 2021
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Biological Research on Addiction

Biological Research on Addiction
Comprehensive Addictive Behaviors and Disorders

by Anonim

  • Publisher : Academic Press
  • Release : 2013-05-17
  • Pages : 758
  • ISBN : 0123983606
  • Language : En, Es, Fr & De
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Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual’s susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. Each article provides glossary, full references, suggested readings, and a list of web resources Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available Discusses the genetic basis of addiction Covers basic science research from a variety of animal studies

Cumulated Index Medicus

Cumulated Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1999
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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