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History of the Synapse

History of the Synapse
A Book

by Max R. Bennett

  • Publisher : CRC Press
  • Release : 2003-09-02
  • Pages : 350
  • ISBN : 0203302540
  • Language : En, Es, Fr & De
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The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.

Nerve Endings

Nerve Endings
The Discovery of the Synapse

by Richard Rapport

  • Publisher : W. W. Norton
  • Release : 2005-05-01
  • Pages : 240
  • ISBN : 9780393337525
  • Language : En, Es, Fr & De
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Two Doctors, the Spaniard Cajal and the Italian Golgi, were racing against each other to find out what brain cells looked like and how they managed to communicate with one another. Both did their most important research in labs set up on their kitchen tables, for lack of better facilities; and both made landmark findings that led to their jointly receiving the 1906 Nobel Prize. Yet one man would find that neurons communicated over a gap, later named the "synapse," while the other would die convinced that every brain cell connected to the next. From Parkinson's to neurosurgery, from the mechanics of memory to clinical depression, modern medicine is ever indebted to the one who interpreted the elusive--and rather extraordinary--anatomy of the nerve cell. This is the story not only of one of the nineteenth century's greatest discoveries but also of the frailty, perseverance, and creativity of human beings.

The Synapse Sequence

The Synapse Sequence
A Book

by Daniel Godfrey

  • Publisher : Titan Books
  • Release : 2018-06-19
  • Pages : 384
  • ISBN : 1785653180
  • Language : En, Es, Fr & De
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The new thrilling sci-fi novel from the author of New Pompeii and Empire of Time. In a future London, humans are watched over by AIs and served by bots. But now that justice and jobs are meted out by algorithm, inequality blooms, and protest is brutally silenced. Anna Glover may be the most hated woman in the troubled city – the media’s scapegoat for an unpopular war. Now she hides from the public eye, investigating neglected cases by using the mind-invading technology of the synapse sequencer to enter witnesses’ memories. When a PI brings her a new high-stakes case, Anna sees a chance for atonement. But soon she is drawn into a plot that threatens to upend her hard-won anonymity and put everyone in danger – even those she hopes to save.

Simulations of Molecules and Processes in the Synapse

Simulations of Molecules and Processes in the Synapse
A Book

by Kaihsu Tai

  • Publisher : Kaihsu Tai
  • Release : 2002
  • Pages : 192
  • ISBN : 049390932X
  • Language : En, Es, Fr & De
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Symposium on the Synapse

Symposium on the Synapse
A Book

by Herbert Spencer Gasser

  • Publisher : Unknown Publisher
  • Release : 1939
  • Pages : 474
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Synapse

The Synapse
Structure and Function

by Virginia M. Pickel,Menahem Segal

  • Publisher : Elsevier
  • Release : 2013-11-16
  • Pages : 512
  • ISBN : 0124186823
  • Language : En, Es, Fr & De
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The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

The Synapse

The Synapse
A Subject Collection from Cold Spring Harbor Perspectives in Biology

by Morgan Sheng,Bernardo Sabatini,Thomas C. Südhof

  • Publisher : Unknown Publisher
  • Release : 2012
  • Pages : 397
  • ISBN : 9781936113026
  • Language : En, Es, Fr & De
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"A subject collection from Cold Spring Harbor perspectives in biology"--T.p. verso.

Structural and Functional Organization of the Synapse

Structural and Functional Organization of the Synapse
A Book

by Johannes W. Hell,Michael D. Ehlers

  • Publisher : Springer Science & Business Media
  • Release : 2008-06-25
  • Pages : 801
  • ISBN : 0387772324
  • Language : En, Es, Fr & De
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This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.

The Synapse

The Synapse
A Book

by Edward George Gray

  • Publisher : Unknown Publisher
  • Release : 1973
  • Pages : 16
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Signaling at the Synapse

Signaling at the Synapse
A Book

by Neuron,Cell

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 149
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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History of the Synapse

History of the Synapse
A Book

by Max R. Bennett

  • Publisher : CRC Press
  • Release : 2001-10-11
  • Pages : 350
  • ISBN : 9789058231321
  • Language : En, Es, Fr & De
GET BOOK

The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.

Beyond the Synapse

Beyond the Synapse
Cell-Cell Signaling in Synaptic Plasticity

by R. Douglas Fields

  • Publisher : Cambridge University Press
  • Release : 2012-11-29
  • Pages : 322
  • ISBN : 9781107411562
  • Language : En, Es, Fr & De
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Formation of synapses and the changes in their connections during life are the basis for learning and memory and recovery from brain disease or injury. Much interest has been focused on how synapses function at the molecular level, while the cell-cell interactions controlling the formation receive far less attention. This book expands the scope of inquiry beyond the synaptic cleft to provide a comprehensive insight into how intercellular signalling enables neurons to communicate beyond the synapse, and to interact with other cells in the brain to alter synaptic connections appropriately. There are chapters devoted to consideration of glia, brain cells which have thus far been ignored in the majority of studies of learning and memory. Writing for academic researchers and professionals, contributors to this book reveal that there is much to learning and memory that lies beyond the synapse.

Folding for the Synapse

Folding for the Synapse
A Book

by Andreas Wyttenbach,Vincent O'Connor

  • Publisher : Springer Science & Business Media
  • Release : 2010-10-22
  • Pages : 318
  • ISBN : 1441970614
  • Language : En, Es, Fr & De
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Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Emotional Modulation of the Synapse

Emotional Modulation of the Synapse

by Christa McIntyre,Jonathan Eric Ploski

  • Publisher : Frontiers Media SA
  • Release : 2015-08-21
  • Pages : 129
  • ISBN : 2889196062
  • Language : En, Es, Fr & De
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Highly emotional events tend to be well remembered. The adaptive value in this is clear – those events that have a bearing on survival should be stored for future use as long-term memories whereas memories of inconsequential events would not as likely contribute to future survival. Enduring changes in the structure and function of synapses, neural circuitry, and ultimately behavior, can be modulated by highly aversive or rewarding experiences. In the last decade, the convergence of cellular, molecular, and systems neuroscience has produced new insights into the biological mechanisms that determine whether a memory will be stored for the long-term or lost forever. This Research Topic brings together leading experts, who work at multiple levels of analysis, to reveal recent discoveries and concepts regarding the synaptic mechanisms of consolidation and extinction of emotionally arousing memories.

Folding for the Synapse

Folding for the Synapse
A Book

by Andreas Wyttenbach,Vincent O'Connor

  • Publisher : Springer
  • Release : 2010-10-25
  • Pages : 318
  • ISBN : 9781441970602
  • Language : En, Es, Fr & De
GET BOOK

Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Chemical Pharmacology of the Synapse

Chemical Pharmacology of the Synapse
A Book

by D. J. Triggle,C. R. Triggle

  • Publisher : Unknown Publisher
  • Release : 1976
  • Pages : 654
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Structural and Functional Organization of the Synapse

Structural and Functional Organization of the Synapse
A Book

by Johannes W. Hell,Michael D. Ehlers

  • Publisher : Springer
  • Release : 2010-11-16
  • Pages : 801
  • ISBN : 9780387568690
  • Language : En, Es, Fr & De
GET BOOK

This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.

The Synapse

The Synapse
Function, Plasticity, and Neurotrophism

by Motoy Kuno,Professor of Physiology Motoy Kuno

  • Publisher : Oxford University Press, USA
  • Release : 1995
  • Pages : 249
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The synapse not only provides a bridge from one nerve cell to the next, its function can also be modified by experience, making it important for learning and memory. This volume provides a review of current concepts in neurobiology with specific reference to neurotransmission and neurotrophism.

The Synapse

The Synapse
A Book

by John Carew Eccles

  • Publisher : Unknown Publisher
  • Release : 1965
  • Pages : 11
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Adhesion, Synaptogenesis, and Maintenance at the Synapse

Adhesion, Synaptogenesis, and Maintenance at the Synapse
A Study on the Function of the Neuroligin Protein

by Gregory Patrick Naughton

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 138
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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