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The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity
A Book

by Denise Faustman

  • Publisher : Academic Press
  • Release : 2018-08-01
  • Pages : 200
  • ISBN : 0081025904
  • Language : En, Es, Fr & De
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The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs. Brings a different perspective on treatment approaches for certain autoimmune conditions Gives insight into the how the BCG vaccine impacts gene expression and the durability of the BCG vaccines in long lasting clinic effects Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment Covers new topics, such as the Epigenetics of tuberculosis, BCG in neurological disease, BCG in early childhood and allergy, BCG in large prevention trials, Gene expression of BCG and re-methylation of genes, and more

The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity
A Book

by Denise Faustman

  • Publisher : Academic Press
  • Release : 2014
  • Pages : 164
  • ISBN : 9780127999647
  • Language : En, Es, Fr & De
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The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity. Editor awarded 2005: Oprah Achievement Award," Top Health Breakthrough by a Female Scientist" Brings into one resource the international scientific literature on a unique way to treat autoimmunity Provides a different perspective on treatment approaches for certain autoimmune conditions Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment

Nutrition and Cardiovascular Health

Nutrition and Cardiovascular Health
A Book

by Paramjit S. Tappia,Heather Blewett

  • Publisher : MDPI
  • Release : 2020-06-17
  • Pages : 278
  • ISBN : 3039288873
  • Language : En, Es, Fr & De
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There is unequivocal experimental, epidemiological, and clinical evidence demonstrating a correlation between diet and increased risk of cardiovascular disease (CVD). While nutritionally-poor diets can have a significant negative impact on cardiovascular health, dietary interventions with specific nutrients and/or functional foods are considered cost-effective and efficient components of prevention strategies. It has been estimated that nutritional factors may be responsible for approximately 40% of all CVD. Indeed, in one of the seminal studies conducted on modifiable risk factors and heart health (the INTERHEART study), >90% of all myocardial infarctions were attributed to preventable environmental factors with nutrition identified as one of the important determinants of CVD. There is an increasing public interest in and scientific investigation into establishing dietary approaches that can be undertaken for the prevention and treatment of CVD. This Special Issue provides an insight into the influential role of nutrition and dietary habits on cardiovascular health and disease, as well as their mechanisms of therapeutic and preventive action.

Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies

Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
A Book

by Babita Agrawal,Stephanie Yanow,Shakti Singh

  • Publisher : Frontiers Media SA
  • Release : 2020-08-27
  • Pages : 129
  • ISBN : 2889639657
  • Language : En, Es, Fr & De
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Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis
Drug Discovery, Drug Delivery, and Disease Prevention

by Rupinder K. Sodhi,Jitender Madan

  • Publisher : Academic Press
  • Release : 2020-10-15
  • Pages : 432
  • ISBN : 0128157631
  • Language : En, Es, Fr & De
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Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments

Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments
A Book

by Anne C. La Flamme,Jacqueline Monique Orian

  • Publisher : Springer
  • Release : 2015-10-07
  • Pages : 235
  • ISBN : 3319255436
  • Language : En, Es, Fr & De
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Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Primary Immunodeficiencies Worldwide

Primary Immunodeficiencies Worldwide
A Book

by Menno C. van Zelm,Antonio Condino-Neto,Mohamed-Ridha Barbouche

  • Publisher : Frontiers Media SA
  • Release : 2020-02-19
  • Pages : 129
  • ISBN : 2889635201
  • Language : En, Es, Fr & De
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Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Periodicum Biologorum

Periodicum Biologorum
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1994
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cumulated Index Medicus

Cumulated Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Infectious Diseases E-Book

Infectious Diseases E-Book
A Book

by Jonathan Cohen,William G Powderly,Steven M. Opal

  • Publisher : Elsevier Health Sciences
  • Release : 2016-06-10
  • Pages : 2016
  • ISBN : 070206338X
  • Language : En, Es, Fr & De
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Drs. Cohen, Powderly and Opal, three of the most-respected names in infectious disease medicine, lead a diverse team of international contributors to bring you the latest knowledge and best practices. Extensively updated, the fourth edition includes brand-new information on advances in diagnosis of infection; Hepatitis C; managing resistant bacterial infections; and many other timely topics. An abundance of photographs and illustrations; a practical, clinically-focused style; highly-templated organization; and robust interactive content combine to make this clinician-friendly resource the fastest and best place to find all of the authoritative, current information you need. Hundreds of full-color photographs and figures provide unparalleled visual guidance. Consistent chapter organization and colorful layouts make for quick searches. Clinically-focused guidance from "Practice Points" demonstrates how to diagnose and treat complicated problems encountered in practice. The "Syndromes by Body System", "HIV and AIDS", and "International Medicine" sections are designed to reflect how practicing specialists think when faced with a patient. Sweeping updates include new or revised chapters on: Hepatitis C and antivirals Fungal infection and newer antifungals Microbiome and infectious diseases as well as advances in diagnosis of infection; Clostridium difficile epidemiology; infection control in the ICU setting; Chlamydia trachomatis infection; acquired syndromes associated with autoantibodies to cytokines;; management of multidrug resistant pathogens; probiotics, polymyxins, and the pathway to developing new antibiotics HIV including HIV and aging, antiretroviral therapy in developing countries, and cure for HIV

Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
A Book

by Changjun Yin,Andreas J.R. Habenicht,Sarajo Mohanta,Pasquale Maffia

  • Publisher : Frontiers Media SA
  • Release : 2017-05-22
  • Pages : 129
  • ISBN : 2889451801
  • Language : En, Es, Fr & De
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The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.

Immunology at a Glance

Immunology at a Glance
A Book

by J. H. L. Playfair,B.M. Chain

  • Publisher : John Wiley & Sons
  • Release : 2009-03-17
  • Pages : 109
  • ISBN : 1405180528
  • Language : En, Es, Fr & De
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This text presents a broad look at immunology with the aid of a series of sketches which show the mechanisms involved in the immunology process. This ninth edition has been completely updated, with new chapters on recognition and receptors and immunity in health and disease.

Immunology

Immunology
A Book

by Ivan Maurice Roitt,Jonathan Brostoff,David K. Male

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 480
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The sixth edition of Roitt's IMMUNOLOGY brings this classic textbook up to date. 250 top quality photographs and over 400 color illustrations bring immunology to life. Case studies have been added, placing immunology in a clinical context. Expanded Critical Thinking sections with detailed feedback test understanding and provide a useful revision tool. Part of an unsurpassed coordinated learning package.

Williams Hematology, 9E

Williams Hematology, 9E
A Book

by Kenneth Kaushansky,Marshall A. Lichtman,Josef Prchal,Marcel M. Levi,Oliver W Press,Linda J Burns,Michael Caligiuri

  • Publisher : McGraw Hill Professional
  • Release : 2015-12-23
  • Pages : 2528
  • ISBN : 0071833013
  • Language : En, Es, Fr & De
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Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2019! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.

Cytokines

Cytokines
A Book

by Anthony Meager

  • Publisher : Unknown Publisher
  • Release : 1990
  • Pages : 291
  • ISBN : 9780335094011
  • Language : En, Es, Fr & De
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In the last few years molecular biologists have discovered a great deal of information about cytokine structures and genes, along with a clarification of the roles of individual cytokines. The possibility that cytokines are involved in the immunopathology of a number of diseases and could therefore be used in new therapeutic techniques has provided the incentive for extensive investigation of these molecules. This book provides an introduction to the cell and molecular biology of cytokines. The text is designed for students, research workers and clinicians who are entering this field for the first time or for those wishing to update their knowledge.

Conference Papers Index

Conference Papers Index
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Monthly. Papers presented at recent meeting held all over the world by scientific, technical, engineering and medical groups. Sources are meeting programs and abstract publications, as well as questionnaires. Arranged under 17 subject sections, 7 of direct interest to the life scientist. Full programs of meetings listed under sections. Entry gives citation number, paper title, name, mailing address, and any ordering number assigned. Quarterly and annual indexes to subjects, authors, and programs (not available in monthly issues).