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The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research
Biology, Husbandry, Diseases, and Research Applications

by Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders

  • Publisher : Academic Press
  • Release : 2019-11-22
  • Pages : 718
  • ISBN : 0128124326
  • Language : En, Es, Fr & De
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The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Zebrafish in Biomedical Research

Zebrafish in Biomedical Research
A Book

by Yusuf Bozkurt

  • Publisher : Unknown Publisher
  • Release : 2020-03
  • Pages : 329
  • ISBN : 9781789859850
  • Language : En, Es, Fr & De
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Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
A Book

by P. Michael Conn

  • Publisher : Springer Science & Business Media
  • Release : 2008
  • Pages : 778
  • ISBN : 1588299333
  • Language : En, Es, Fr & De
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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Laboratory Fish in Biomedical Research

Laboratory Fish in Biomedical Research
Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida

by Livia d'Angelo,Paolo de Girolamo

  • Publisher : Academic Press
  • Release : 2021-09-04
  • Pages : 366
  • ISBN : 0128212454
  • Language : En, Es, Fr & De
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Fish, and particularly zebrafish, have become the fastest-growing segment of the research population. They offer several advantages, in terms of biology and technologies to apply, and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida addresses the relevant and increasing need to collect cutting-edge knowledge on husbandry, maintenance, welfare and experimental protocols of the most common freshwater species under standard laboratory conditions. Provides husbandry and management protocols, devices and water systems; Shows strength and weakness of breeding; Explores potential scientific applications and experimental protocols. with regards to the most used freshwater fish used for scientific purposes.

Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing

Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing
An Annotated Bibliography

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1994
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Zebrafish

Zebrafish
A Book

by Christiane Nusslein-Volhard,Ralf Dahm

  • Publisher : Oxford University Press
  • Release : 2002-09-19
  • Pages : 303
  • ISBN : 9780199638086
  • Language : En, Es, Fr & De
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The zebrafish has become one of the most important model organisms to study biologial processes in vivo. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. The next few years will see the completion of large scale initiatives that exploit the zebrafish as a model system for the understanding of gene function in vertebrates, including the sequencing of the genome. The zebrafish will therefore play an increasingly important role in the future of biomedical research. Whole genome sequencing projects, such as the human genome project, have led to the isolation of tens of thousands of genes for which the in vivo function is unknown. It is therefore likely that an increasing number of researchers will turn to organisms such as the zebrafish to understand the in vivo requirement for the proteins these genes encode. Recent technical advances now allow the rapid testing of in vivo function of as yet uncharacterised genes in zebrafish in large numbers and at a speed that is impossible in other systems. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

Advances in Biomedical Sciences and Engineering

Advances in Biomedical Sciences and Engineering
A Book

by S. C. Tjong

  • Publisher : Bentham Science Publishers
  • Release : 2010-06-10
  • Pages : 327
  • ISBN : 1608050408
  • Language : En, Es, Fr & De
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"This authoritative reference provides updated information on the fundamental aspects and applications of biomaterials and biomedical sciences. It includes nickel-titanium alloys with superelasticity and shape memory effect, bioactive bone cement for ortho"

Advancements of Mass Spectrometry in Biomedical Research

Advancements of Mass Spectrometry in Biomedical Research
A Book

by Alisa G. Woods,Costel C. Darie

  • Publisher : Springer
  • Release : 2014-06-20
  • Pages : 600
  • ISBN : 3319060686
  • Language : En, Es, Fr & De
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This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Biomedical Sciences Instrumentation

Biomedical Sciences Instrumentation
Proceedings of the ... Annual Rocky Mountain Bioengineering Symposium and the ... International ISA Biomedical Sciences Instrumentation Symposium Held ...

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1979
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Fish Physiology: Zebrafish

Fish Physiology: Zebrafish
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2010-06-23
  • Pages : 468
  • ISBN : 9780080961378
  • Language : En, Es, Fr & De
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This cutting-edge resource includes up-to-date information on zebrafish physiology and the tools used to study it, not only as a model species for studies of other vertebrates but with application for studies of human disease and aquatic toxicology. The utility of zebrafish for physiological research is based on several key features including i) a "fully" sequenced genome, ii) rapid (~3 month) generation times), iii) their capacity to produce large numbers of externally fertilized eggs, iv) optical transparency of embryos and larvae, and v) the applicability of reverse and forward genetics to assess gene function. Gene knockdown in embryos and the production of transgenic strains are now standard techniques being used to assess physiology. This book will be of keen interest not only to the typical readers of Fish Physiology but also to biomedical researchers, toxicologists and developmental biologists. Integrates and synthesizes the biology of the zebrafish under one cover Features contributions from the leading researchers in their fields Reaches a wider audience of researchers and biologists with its broad inclusion of subjects relating to zebrafish physiology

Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008-05
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Model Organisms in Drug Discovery

Model Organisms in Drug Discovery
A Book

by Pamela M. Carroll,Kevin Fitzgerald

  • Publisher : John Wiley & Sons
  • Release : 2003-11-21
  • Pages : 288
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signalling pathways which "define" humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer’s disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems. Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future. Leading experts in the field provide detailed accounts of model organism research that have impacted on specific therapeutic areas and they examine state-of-the-art applications of model systems, describing real life applications and their possible impact in the future. This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.

Zebrafish Protocols for Neurobehavioral Research

Zebrafish Protocols for Neurobehavioral Research
A Book

by Allan V. Kalueff,Adam Michael Stewart

  • Publisher : Humana Press
  • Release : 2012-06-06
  • Pages : 357
  • ISBN : 9781617795961
  • Language : En, Es, Fr & De
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Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

DNA and Cell Biology

DNA and Cell Biology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Research resources reporter

Research resources reporter
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1999
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Science

Science
A Book

by John Michels (Journalist)

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Aquaculture Magazine

Aquaculture Magazine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Genome Research

Genome Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Biomedical Models and Resources

Biomedical Models and Resources
Current Needs and Future Opportunities

by National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on New and Emerging Models in Biomedical and Behavioral Research

  • Publisher : National Academies Press
  • Release : 1998-02-16
  • Pages : 84
  • ISBN : 0309060354
  • Language : En, Es, Fr & De
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Printbegrænsninger: Der kan printes 10 sider ad gangen og max. 40 sider pr. session.

Experimental Biology and Medicine

Experimental Biology and Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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