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Therapeutic Drug Monitoring

Therapeutic Drug Monitoring
Newer Drugs and Biomarkers

by Amitava Dasgupta

  • Publisher : Academic Press
  • Release : 2012-06-07
  • Pages : 468
  • ISBN : 0123854687
  • Language : En, Es, Fr & De
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Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques

Applied Pharmacokinetics & Pharmacodynamics

Applied Pharmacokinetics & Pharmacodynamics
Principles of Therapeutic Drug Monitoring

by Michael E. Burton

  • Publisher : Lippincott Williams & Wilkins
  • Release : 2006
  • Pages : 867
  • ISBN : 9780781744317
  • Language : En, Es, Fr & De
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The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.

Essentials of Therapeutic Drug Monitoring

Essentials of Therapeutic Drug Monitoring
A Book

by Benjamin Gerson

  • Publisher : Igaku-Shoin Medical Publishers
  • Release : 1983
  • Pages : 463
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

Advances in Chromatographic Techniques for Therapeutic Drug Monitoring
A Book

by Amitava Dasgupta

  • Publisher : CRC Press
  • Release : 2009-10-06
  • Pages : 475
  • ISBN : 1420067591
  • Language : En, Es, Fr & De
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For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp

Therapeutic Drug Monitoring

Therapeutic Drug Monitoring
A Book

by Gerald E. Schumacher

  • Publisher : McGraw-Hill/Appleton & Lange
  • Release : 1995
  • Pages : 684
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)

Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)
A Book

by Steven H.Y. Wong,Irving Sunshine

  • Publisher : CRC Press
  • Release : 2017-11-22
  • Pages : 366
  • ISBN : 1351364278
  • Language : En, Es, Fr & De
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Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.

Therapeutic Drug Monitoring

Therapeutic Drug Monitoring
A Book

by B. Widdrop

  • Publisher : Unknown Publisher
  • Release : 1985
  • Pages : 369
  • ISBN : 9780598097132
  • Language : En, Es, Fr & De
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Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics
A Book

by Georg Hempel

  • Publisher : Elsevier
  • Release : 2019-10-17
  • Pages : 380
  • ISBN : 0444640673
  • Language : En, Es, Fr & De
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Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. Presents a unique, interdisciplinary approach that appeals to a wide range of users Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments Features additional therapeutic drugs to reflect the rising number of immunocompromised patients Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories

Applied Pharmacokinetics

Applied Pharmacokinetics
Principles of Therapeutic Drug Monitoring

by William E. Evans,Jerome J. Schentag,William J. Jusko

  • Publisher : Applied Therapeutics, Incorporated
  • Release : 1992
  • Pages : 1202
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.

Clinical Challenges in Therapeutic Drug Monitoring

Clinical Challenges in Therapeutic Drug Monitoring
Special Populations, Physiological Conditions and Pharmacogenomics

by William Clarke,Amitava Dasgupta

  • Publisher : Elsevier
  • Release : 2016-07-21
  • Pages : 376
  • ISBN : 0128020520
  • Language : En, Es, Fr & De
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Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window

Therapeutic drug monitoring

Therapeutic drug monitoring
clinical guide

by Michael Hallworth,Ian Watson

  • Publisher : Unknown Publisher
  • Release : 2010
  • Pages : 134
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology

Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology
A Book

by Irving Sunshine

  • Publisher : CRC Press
  • Release : 2019-10-07
  • Pages : 806
  • ISBN : 9780367402839
  • Language : En, Es, Fr & De
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Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr

Analytical Methods for Therapeutic Drug Monitoring and Toxicology

Analytical Methods for Therapeutic Drug Monitoring and Toxicology
A Book

by Q. Alan Xu,Timothy L. Madden

  • Publisher : John Wiley & Sons
  • Release : 2011-04-12
  • Pages : 520
  • ISBN : 9780470922798
  • Language : En, Es, Fr & De
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This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.

A Textbook for the Clinical Application of Therapeutic Drug Monitoring

A Textbook for the Clinical Application of Therapeutic Drug Monitoring
A Book

by William James Taylor,Mary H. Diers Caviness

  • Publisher : Abbott Laboratories Diagnostics Division
  • Release : 1986
  • Pages : 487
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Therapeutic Drug Monitoring and Clinical Biochemistry

Therapeutic Drug Monitoring and Clinical Biochemistry
A Book

by Mike Hallworth,Nigel Capps

  • Publisher : Amer Assn for Clinical Chemistry
  • Release : 1993
  • Pages : 178
  • ISBN : 9780902429055
  • Language : En, Es, Fr & De
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This text considers the close inter-relationship of therapeutic drug monitoring and clinical biochemistry. It covers principles of TDM, looking at drug dosage and effect; clinical monitoring and pharmacokinetics; interpretation and response; and near-patient testing. It also includes information on methodology, dosage prediction, drug structure, sampling requirements and target range. The drugs covered include anti-convulsants; aminoglycosides; lithium; anti-arrythmics; xanthines; cyclosporine; methotrexate; and tricyclics. The work also contains case studies.

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography
A Book

by Steven H.Y. Wong

  • Publisher : Routledge
  • Release : 2017-09-19
  • Pages : 512
  • ISBN : 135140847X
  • Language : En, Es, Fr & De
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First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

The Basic Principles of Therapeutic Drug Monitoring

The Basic Principles of Therapeutic Drug Monitoring
A Book

by American Association for Clinical Chemistry. Education Committee,American Association for Clinical Chemistry. Southeast Section

  • Publisher : Unknown Publisher
  • Release : 1976
  • Pages : 95
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Drug Assay

Drug Assay
The Strategy of Therapeutic Drug Monitoring

by Sumner M. Kalman,Dennis R. Clark

  • Publisher : Unknown Publisher
  • Release : 1979
  • Pages : 192
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Interpretations in Therapeutic Drug Monitoring

Interpretations in Therapeutic Drug Monitoring
A Book

by Daniel M. Baer,William R. Dito

  • Publisher : Amer Society of Clinical
  • Release : 1981
  • Pages : 388
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Therapeutic Drug Monitoring

Therapeutic Drug Monitoring
A Market Overview

by Louise Olliver,Clinica (Firm)

  • Publisher : Unknown Publisher
  • Release : 1989
  • Pages : 61
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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