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Information Resources in Toxicology

Information Resources in Toxicology
Volume 2: The Global Arena

by Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes

  • Publisher : Academic Press
  • Release : 2020-05-15
  • Pages : 808
  • ISBN : 0128216123
  • Language : En, Es, Fr & De
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This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Opens with an overview of the international toxicology scene, organizations and activities involved with both the science and regulatory framework, and a specific look at the European Union’s efforts. Offers an extensive collection of chapters covering over 40 countries and their toxicological infrastructure which includes listings of major books and journals, organizations, professional societies, universities, poison control centers, legislation, and online databases. Provides the Second Edition of the International Union of Pure and Applied Chemistry’s Glossary of Terms Used in Toxicology, a carefully constructed and peer reviewed collation of critical terms in the science. Concludes with a potpourri of quotes concerning toxicology and their use in the arts and popular culture. Paired with Volume One, which offers chapters on a host of toxicology sub-disciplines, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over120 chapters contributions by experts and leaders in the field.

Food Toxicology

Food Toxicology
A Book

by Debasis Bagchi,Anand Swaroop

  • Publisher : CRC Press
  • Release : 2016-11-25
  • Pages : 562
  • ISBN : 1315354241
  • Language : En, Es, Fr & De
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Food toxicology studies how natural or synthetic poisons and toxicants in diverse food products cause harmful, detrimental, or adverse side effects in living organisms. Food toxicology is an important consideration as food supply chain is becoming more multinational in origin, and any contamination or toxic manifestation may cause serious, wide-spread adverse health effects. Food Toxicology covers various aspects of food safety and toxicology, including the study of the nature, properties, effects, and detection of toxic substances in food and their disease manifestations in humans. It will also include other aspects of consumer product safety. The first two chapters discuss the measurement of toxicants and toxicity and the importance of dose-response in food toxicology. Additional chapters discuss the aspects of food associated carcinogenesis and food-derived chemical carcinogenesis, food allergy, pathogens associated with fruits and vegetables, and the detrimental effects of radionuclides exposure. The chapters also cover the most important heavy metal contaminants, namely mercury, lead and vanadium, and Fluoride toxicity, which is extensively discussed in its own chapter. Toxicologists, scientists, researchers in food toxicology, nutritionists, and public health care professionals will find valuable information in this book on all possible intricate areas of food toxicology.

Ovarian Toxicology

Ovarian Toxicology
A Book

by Patricia B. Hoyer

  • Publisher : CRC Press
  • Release : 2013-04-08
  • Pages : 248
  • ISBN : 0203509234
  • Language : En, Es, Fr & De
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In recent years, there has been an alarming increase in environmental by-products that may be harmful to ovarian function. Along with this dangerous situation, the modern trend toward delaying motherhood poses immediate concerns regarding the long-term impact of environmental risks on human fertility. The uncertainty of our reproductive future intensifies the need for a single reference that investigates the chemicals with the potential to jeopardize fertility. The only known text that deals specifically with toxicity in the ovary, Ovarian Toxicology updates our current understanding of the effects of environmental chemicals on ovarian function. This new title in the Target Organ Toxicology Series presents an overview of ovarian physiology, examines the key ovarian target sites, assesses the effects of specific chemicals demonstrated in animal studies, and evaluates related human epidemiological data. Featuring the most complete review available of ovarian metabolism of xenobiotics, chapters also discuss ovarian cancer and modeling and testing for ovarian effects. With its clear handling of data and issues that are crucial to fertility studies, this comprehensive exploration of ovarian toxicology identifies the realistic risks for damage that our environment has the potential to inflict. It will be welcomed by toxicologists and ovarian physiologists, those in the pharmaceutical industries and regulatory agencies, and postgraduate researchers striving to safeguard women's fertility and ensure our reproductive future.

Occupational Toxicology

Occupational Toxicology
A Book

by Chris Winder,Neill H. Stacey

  • Publisher : CRC Press
  • Release : 2004-02-11
  • Pages : 624
  • ISBN : 1482289288
  • Language : En, Es, Fr & De
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Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment.

Fundamentals of Toxicology

Fundamentals of Toxicology
Essential Concepts and Applications

by PK Gupta

  • Publisher : Academic Press
  • Release : 2016-08-26
  • Pages : 422
  • ISBN : 0128054034
  • Language : En, Es, Fr & De
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Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

In Vitro Toxicology

In Vitro Toxicology
A Book

by Alok Dhawan,Seok (Soga) Kwon

  • Publisher : Academic Press
  • Release : 2017-11-13
  • Pages : 248
  • ISBN : 0128047712
  • Language : En, Es, Fr & De
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In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing

Toxicology

Toxicology
A Book

by Hans Marquardt,Siegfried G. Schäfer,Roger O. McClellan,Frank Welsch

  • Publisher : Academic Press
  • Release : 1999-10-05
  • Pages : 1330
  • ISBN : 0080543111
  • Language : En, Es, Fr & De
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Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments. Key Features * Comprehensive text, covering all aspects of the field of toxicology * Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects * Identifies the various classes of chemical compounds responsible for the toxic effects * Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention * Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables

Introduction to Toxicology, Third Edition

Introduction to Toxicology, Third Edition
A Book

by John Timbrell

  • Publisher : CRC Press
  • Release : 2001-11-15
  • Pages : 215
  • ISBN : 9780415247634
  • Language : En, Es, Fr & De
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Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Handbook of Arsenic Toxicology

Handbook of Arsenic Toxicology
A Book

by Swaran Jeet Singh Flora

  • Publisher : Academic Press
  • Release : 2014-12-26
  • Pages : 752
  • ISBN : 0124199550
  • Language : En, Es, Fr & De
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Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health. The book takes readings systematically through the target organs, before detailing current preventative and counter measures. This reference enables readers to effectively assess the risks related to arsenic, and provide a comprehensive look at arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasure

Review of Current DHHS, DOE, and EPA Research Related to Toxicology

Review of Current DHHS, DOE, and EPA Research Related to Toxicology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Medical jurisprudence, forensic medicine and toxicology,. v. 2, 1894

Medical jurisprudence, forensic medicine and toxicology,. v. 2, 1894
A Book

by Rudolph August Witthaus

  • Publisher : Unknown Publisher
  • Release : 1894
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A Treatise on materia medica (including therapeutics and toxicology) v. 1, 1883

A Treatise on materia medica (including therapeutics and toxicology) v. 1, 1883
A Book

by Hermann Nothnagel

  • Publisher : Unknown Publisher
  • Release : 1883
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Plant Toxicology, Fourth Edition

Plant Toxicology, Fourth Edition
A Book

by Bertold Hock,Erich F. Elstner

  • Publisher : CRC Press
  • Release : 2004-09-28
  • Pages : 664
  • ISBN : 9780203023884
  • Language : En, Es, Fr & De
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In order to keep track of all the compounds and pathogens affecting plant metabolism and development, you would need to spend all your waking hours combing periodicals and the Internet in dozens of languages, as new toxins via pollutants and migratory or mutant pathogens are being discovered every day. Plant Toxicology, Fourth Edition starts with a basic overview of the plant as a complex living organism. The first chapters introduce plant structure and organization. Starting with the cell as the smallest elementary unit, the emphasis is on plant-specific features with respect to their susceptibility to environmental contaminants. Hock and Elstner, who between them have published over 500 original papers on plants and plant disease, called upon experts from across the world to contribute to this essential text. The book analyzes processes central to plant metabolism, including uptake, distribution, and secretion of toxic material, and focuses on the recognition and prevention of damage associated with environmental pollutants. It studies diseases caused by viruses, subviral organisms, phytoplasmas, fungal and bacterial pathogens. Learn about Pathology in Plants as an Integral Interconnected Facet of their Environment The text is designed to enable you to classify and target specific forms of plant damage. Equally important, it never loses sight of the princple that plants are not isolated organisms, but rather exist as participants in complex environments, which must be taken into account when studying the delivery and impact of toxins. Supplying more than 1500 current references, Plant Toxicology, Fourth Edition is required reading for all plant, crop, soil, and environmental scientists; botanists; agronomists; agriculturists; horticulturists; biochemists; foresters; plant growers; and upper level undergraduate and graduate students in these disciplines. Features

A Manual of Toxicology

A Manual of Toxicology
Including the Consideration of the Nature, Properties, Effects, and Means of Detection of Poisons, More Especially in Their Medico-legal Relations

by John James Reese

  • Publisher : Unknown Publisher
  • Release : 1874
  • Pages : 495
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Notes on Toxicology, etc

Notes on Toxicology, etc
A Book

by John James EBERLE

  • Publisher : Unknown Publisher
  • Release : 1876
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Text-book of Medical Jurisprudence and Toxicology

Text-book of Medical Jurisprudence and Toxicology
A Book

by John James Reese

  • Publisher : Unknown Publisher
  • Release : 1894
  • Pages : 624
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The History of Alternative Test Methods in Toxicology

The History of Alternative Test Methods in Toxicology
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2018-10-20
  • Pages : 352
  • ISBN : 0128136987
  • Language : En, Es, Fr & De
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The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.

Essentials of Chemistry and Toxicology, for the Use of Students in Medicine

Essentials of Chemistry and Toxicology, for the Use of Students in Medicine
A Book

by Rudolph August Witthaus

  • Publisher : Unknown Publisher
  • Release : 1888
  • Pages : 294
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Genetically Modified Model Report on Toxicology and Carcinogenesis Study of Glycidol (CAS No. 556-52-5) in Genetically Modified Haploinsufficient P16Ink4a/p19Arf Mice (Gavage Study)

Genetically Modified Model Report on Toxicology and Carcinogenesis Study of Glycidol (CAS No. 556-52-5) in Genetically Modified Haploinsufficient P16Ink4a/p19Arf Mice (Gavage Study)
A Book

by J. K. Dunnick

  • Publisher : DIANE Publishing
  • Release : 2008-06
  • Pages : 81
  • ISBN : 1437902243
  • Language : En, Es, Fr & De
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Glycidol is used as a chemical intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, Glycidol ethers, and amines. Glycidol was nominated for carcinogenecity study by the Environmental Protection Agency (EPA). Glycidol was selected for study in the haploinsufficient p16Ink4a/p19Arf mouse because it was found to be carcinogenic in rats and mice in conventional 2-year rodent studies (NTP, 1990), but was negative in a study in p53+/- mice (Tennant et al., 1999). In this study, male and female mice received Glycidol (greater than 95% pure) by gavage for 40 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.

Lectures on Medical Jurisprudence and Toxicology

Lectures on Medical Jurisprudence and Toxicology
As Delivered at the London Hospital

by Frederick John Smith

  • Publisher : Unknown Publisher
  • Release : 1900
  • Pages : 396
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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