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Translational Biotechnology

Translational Biotechnology
A Journey from Laboratory to Clinics

by Yasha Hasija

  • Publisher : Academic Press
  • Release : 2021-01-29
  • Pages : 452
  • ISBN : 0128219734
  • Language : En, Es, Fr & De
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Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Pharmaceutical Biotechnology

Pharmaceutical Biotechnology
A Book

by Carlos A. Guzmán,Giora Z. Feuerstein

  • Publisher : Springer Science & Business Media
  • Release : 2010-01-01
  • Pages : 276
  • ISBN : 9781441911322
  • Language : En, Es, Fr & De
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Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.

Basic Biotechnology

Basic Biotechnology
A Book

by Colin Ratledge,Bjorn Kristiansen

  • Publisher : Cambridge University Press
  • Release : 2006-05-25
  • Pages : 666
  • ISBN : 0521840317
  • Language : En, Es, Fr & De
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Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. A distinctive feature of this text are the discussions of the public perception of biotechnology and the business of biotechnology, which set the science in a broader context. This comprehensive textbook is essential reading for all students of biotechnology and applied microbiology, and for researchers in biotechnology industries.

Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges

Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges
A Book

by Stefania Mondello,Anwarul Hasan,Deborah Shear

  • Publisher : Frontiers Media SA
  • Release : 2020-02-03
  • Pages : 329
  • ISBN : 2889634493
  • Language : En, Es, Fr & De
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Biotechnology

Biotechnology
Applying the Genetic Revolution

by David P. Clark,Nanette Jean Pazdernik

  • Publisher : Elsevier
  • Release : 2009
  • Pages : 750
  • ISBN : 0121755525
  • Language : En, Es, Fr & De
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Finally, the text includes a very thought-provoking chapter on the bioethics of these new advances and applications of today's world of biotechnology, which stimulates the student to think rather than memorize."--BOOK JACKET.

Molecular Biology and Biotechnology of Plant Organelles

Molecular Biology and Biotechnology of Plant Organelles
Chloroplasts and Mitochondria

by Henry Daniell, Ph.D.,Christine D. Chase

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-04
  • Pages : 659
  • ISBN : 1402031661
  • Language : En, Es, Fr & De
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We have taught plant molecular biology and biotechnology at the undergraduate and graduate level for over 20 years. In the past few decades, the field of plant organelle molecular biology and biotechnology has made immense strides. From the green revolution to golden rice, plant organelles have revolutionized agriculture. Given the exponential growth in research, the problem of finding appropriate textbooks for courses in plant biotechnology and molecular biology has become a major challenge. After years of handing out photocopies of various journal articles and reviews scattered through out the print and electronic media, a serendipitous meeting occurred at the 2002 IATPC World Congress held in Orlando, Florida. After my talk and evaluating several posters presented by investigators from my laboratory, Dr. Jacco Flipsen, Publishing Manager of Kluwer Publishers asked me whether I would consider editing a book on Plant Organelles. I accepted this challenge, after months of deliberations, primarily because I was unsuccessful in finding a text book in this area for many years. I signed the contract with Kluwer in March 2003 with a promise to deliver a camera-ready textbook on July 1, 2004. Given the short deadline and the complexity of the task, I quickly realized this task would need a co-editor. Dr. Christine Chase was the first scientist who came to my mind because of her expertise in plant mitochondria, and she readily agreed to work with me on this book.

Career Development in Bioengineering and Biotechnology

Career Development in Bioengineering and Biotechnology
A Book

by Guruprasad Madhavan,Barbara Oakley,Luis Kun

  • Publisher : Springer Science & Business Media
  • Release : 2009-01-07
  • Pages : 536
  • ISBN : 9780387764955
  • Language : En, Es, Fr & De
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This indispensable guide provides a roadmap to the broad and varied career development opportunities in bioengineering, biotechnology, and related fields. Eminent practitioners lay out career paths related to academia, industry, government and regulatory affairs, healthcare, law, marketing, entrepreneurship, and more. Lifetimes of experience and wisdom are shared, including "war stories," strategies for success, and discussions of the authors’ personal views and motivations.

Biotechnology and Biopharmaceuticals

Biotechnology and Biopharmaceuticals
Transforming Proteins and Genes into Drugs

by Anonim

  • Publisher : John Wiley & Sons
  • Release : 2013-09-19
  • Pages : 744
  • ISBN : 1118659988
  • Language : En, Es, Fr & De
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Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.

Biotechnology Annual Review

Biotechnology Annual Review
A Book

by M. Raafat El-Gewely

  • Publisher : Elsevier
  • Release : 2007-11-14
  • Pages : 378
  • ISBN : 9780080553689
  • Language : En, Es, Fr & De
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Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, recent advances in all-protein chromophore technology- to topics that are focused on sequencing and recombinant vaccines. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training. * Includes over 200 figures with more than 60 tables * Discusses valuable information on pharming & transgenic plants * Provides detailed information on the production of plasmid DNA for pharmaceutical use

Mammalian Cell Biotechnology in Protein Production

Mammalian Cell Biotechnology in Protein Production
A Book

by Hansjörg Hauser,Roland Wagner

  • Publisher : Walter de Gruyter
  • Release : 1997-01-01
  • Pages : 510
  • ISBN : 3110809281
  • Language : En, Es, Fr & De
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„Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt.“ Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München

Advances in Biotechnology Research and Application: 2013 Edition

Advances in Biotechnology Research and Application: 2013 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2013-06-21
  • Pages : 427
  • ISBN : 1481694030
  • Language : En, Es, Fr & De
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Advances in Biotechnology Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bioelectronics. The editors have built Advances in Biotechnology Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioelectronics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biotechnology & Genetic Engineering Reviews

Biotechnology & Genetic Engineering Reviews
Volume 25

by Stephen Harding

  • Publisher : Nottingham University Press
  • Release : 2009-04-01
  • Pages : 464
  • ISBN : 1904761666
  • Language : En, Es, Fr & De
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Containing more than a dozen original, major review articles from authors published in leading journals and covering important developments in industrial, agricultural, and medical applications of biotechnology, this newest edition from the well-established hardcover review series focuses primarily on the genetic manipulation of organisms. Covering issues ranging from gene expression and genetic regulations to plant bioreactors and enzymatic processing, this reference will benefit students in the fields of biochemistry, genetics, molecular biology, and pharmaceutical sciences.

Plant Biotechnology

Plant Biotechnology
Biotechnology

by Shain-dow Kung,Charles J. Arntzen

  • Publisher : Elsevier
  • Release : 2014-05-12
  • Pages : 448
  • ISBN : 1483192601
  • Language : En, Es, Fr & De
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Plant Biotechnology provides an introduction to the fundamental life processes and reviews topics relevant to plant biotechnology. This book discusses the manipulation of biological systems to solve practical problems in industry or agriculture. Organized into four parts encompassing 18 chapters, this book begins with an overview of the fundamental techniques essential to plant biotechnology. This text then describes the various aspects of the regulation of gene expression in plants and reviews the molecular architecture of plant genes. Other chapters consider chloroplast genome from various organisms and present the practical examples of the significance and uses of biotechnology in crop improvement. This book discusses as well the methods for inducing plant gene expression in heterologous prokaryotic and eukaryotic systems. The final chapter deals with the potential for using gene transfer technology for crop improvement. This book is a valuable resource for plant physiologists, biochemists, plant scientists, genetic engineers, and evolutionary biologists.

Translational Medicine

Translational Medicine
The Future of Therapy?

by James Mittra,Christopher-Paul Milne

  • Publisher : CRC Press
  • Release : 2016-04-19
  • Pages : 294
  • ISBN : 9814364843
  • Language : En, Es, Fr & De
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This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field. The contributors explore the dynamic interactions and key challenges in translating new science into viable therapies for the clinic, which includes recognizing the importance of social, commercial, and regulatory environments in addition to good science.

Pharmaceutical Biotechnology

Pharmaceutical Biotechnology
Concepts and Applications

by Gary Walsh

  • Publisher : John Wiley & Sons
  • Release : 2013-04-25
  • Pages : 504
  • ISBN : 111868575X
  • Language : En, Es, Fr & De
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Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Biotechnology in Agriculture

Biotechnology in Agriculture
Proceedings of the First Asia-Pacific Conference on Agricultural Biotechnology, Beijing, China, 20–24 August 1992

by Chongbiao You,Zhangliang Chen,Yong Ding

  • Publisher : Springer Science & Business Media
  • Release : 1993-03-31
  • Pages : 522
  • ISBN : 9780792321682
  • Language : En, Es, Fr & De
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The First Asia --- Pacific Conference on Agricultural Biotechnology was held in Beijing, China on 20-24, August, 1992. Over half the population in the world is in the Asian and Pacific Region. With an increasing population and decreasing farming lands, it is important to develop agricultural biotechnology for improvement of the productivity, profitability and stability of the farming system. The Conference's main objectives were to bring together scientists working in different fields of agricultural biotechnology to stimulate discussion on this important process and to have an appraisal of the most recent studies concerning genetic manipulation of plants, plant cell and tissue culture, plant gene regulation, plant-microbe interaction, animal biotechnology etc. The Conference was attended by 391 scientists from different countries and regions. This volume presents the contributions of the lectures and a selected number of posters, which are an up-to-date account of the state of knowledge on agricultural biotechnology. The book provides a valuable reference source not only for specialists in agricultural biotechnology, but also for researchers working on related aspects of agronomy, biochemistry, genetics, molecular biology, microbiology and animal sciences. It is with great pleasure to acknowledge the contributions of the authors in assuring the prompt publication of this volume. We would also extend our sincere thank to Kluwer Academic Publishers for the publication of these proceedings.

Rabbit Biotechnology

Rabbit Biotechnology
Rabbit genomics, transgenesis, cloning and models

by Louis-Marie Houdebine,Jianglin Fan

  • Publisher : Springer Science & Business Media
  • Release : 2009-04-24
  • Pages : 136
  • ISBN : 9048122279
  • Language : En, Es, Fr & De
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Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.

Aquaculture and Fisheries Biotechnology

Aquaculture and Fisheries Biotechnology
Genetic Approaches

by Rex A. Dunham

  • Publisher : CABI
  • Release : 2011
  • Pages : 495
  • ISBN : 1845936515
  • Language : En, Es, Fr & De
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This second edition covers topics essential to the study of fish genetics, including qualitative and quantitative traits, crossbreeding, inbreeding, genetic drift, hybridization, selection programs, polyploidy, genomics and cloning. Fully updated and tailored for students with a new layout and format, "Aquaculture and Fisheries Biotechnology and Genetics" also addresses environmental risk, food safety and government regulation of transgenic aquatic organisms, commercial applications of fish biotechnology and future issues in fish genetics. It is essential reading for students of fish genetics and fish molecular genetics.

Fundamentals of Food Biotechnology

Fundamentals of Food Biotechnology
A Book

by Byong H. Lee

  • Publisher : John Wiley & Sons
  • Release : 2014-12-01
  • Pages : 544
  • ISBN : 1118384911
  • Language : En, Es, Fr & De
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Food biotechnology is the application of modern biotechnologicaltechniques to the manufacture and processing of food, for examplethrough fermentation of food (which is the oldest biotechnologicalprocess) and food additives, as well as plant and animal cellcultures. New developments in fermentation and enzyme technologicalprocesses, molecular thermodynamics, genetic engineering, proteinengineering, metabolic engineering, bioengineering, and processesinvolving monoclonal antibodies, nanobiotechnology and quorumsensing have introduced exciting new dimensions to foodbiotechnology, a burgeoning field that transcends many scientificdisciplines. Fundamentals of Food Biotechnology, 2nd edition is basedon the author’s 25 years of experience teaching on a foodbiotechnology course at McGill University in Canada. The book willappeal to professional food scientists as well as graduate andadvanced undergraduate students by addressing the latest excitingfood biotechnology research in areas such as genetically modifiedfoods (GMOs), bioenergy, bioplastics, functionalfoods/nutraceuticals, nanobiotechnology, quorum sensing andquenching. In addition, cloning techniques for bacterial and yeastenzymes are included in a “New Trends and Tools”section and selected references, questions and answers appear atthe end of each chapter. This new edition has been comprehensively rewritten andrestructured to reflect the new technologies, products and trendsthat have emerged since the original book. Many new aspectshighlight the short and longer term commercial potential of foodbiotechnology.

Expenditure Budget

Expenditure Budget
A Book

by India

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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