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Translational Endocrinology of Bone

Translational Endocrinology of Bone
Reproduction, Metabolism, and the Central Nervous System

by Gerard Karsenty

  • Publisher : Academic Press
  • Release : 2012-12-31
  • Pages : 236
  • ISBN : 0124158595
  • Language : En, Es, Fr & De
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The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology. Summarizes the latest research and translational applications of how the varied growth and development of bone affects appetite, metabolism, reproduction, and a wide range of endocrine functions Provides a common language for bone biologists, endocrinologists, osteologists, and other researchers, such as neuroscientists, who study appetite, fuel metabolism and diabetes, to discuss the development of translational research and new therapeutic strategies for bone, metabolic, and neuro-endocrine diseases. Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone research and therapeutics, as opposed to searching through thousands of journal articles

Diabetic Bone Disease

Diabetic Bone Disease
Basic and Translational Research and Clinical Applications

by Beata Lecka-Czernik,John L. Fowlkes

  • Publisher : Springer
  • Release : 2015-10-12
  • Pages : 241
  • ISBN : 3319164023
  • Language : En, Es, Fr & De
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Providing the most up-to-date research and current clinical knowledge of diabetic bone disease and the challenges still facing the research and clinical care communities, this book unites insights from endocrinology and orthopedics to create a truly unique text. The first part covers clinical and pre-clinical applications and research. The first two chapters present the clinical and epidemiological data about diabetic bone disease, evaluated and reviewed for type 1 and type 2, respectively. This is followed by discussions of how the propensity to fracture in diabetic bone disease can impact fracture risk assessments and how it can be adjusted for using current clinically relevant fracture risk models. A comprehensive overview of orthopedic complications observed in diabetes is next, as well as a focus on the consequences of diabetes on periodontal disease. Other topics include the utility of skeletal biomarkers in assessing diabetic bone disease, how drugs used to treat diabetes may also have skeletal consequences, and the possibility that diabetes may fundamentally impact early progenitor cells of various bone lineages and thus globally impact bone. The second part covers biomechanics and bone quality in diabetes: how diabetes ultimately may impact the architecture, integrity, and quality of bone. Utilizing the expertise of top researcher and clinicians in diabetic bone disease in one comprehensive text, this volume will be a useful and thought-provoking resource for endocrinologists and orthopedic surgeons alike.

Bone Regulators and Osteoporosis Therapy

Bone Regulators and Osteoporosis Therapy
A Book

by Paula H. Stern

  • Publisher : Springer Nature
  • Release : 2020-11-28
  • Pages : 518
  • ISBN : 3030573788
  • Language : En, Es, Fr & De
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This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.

Advances in Diabetes

Advances in Diabetes
Novel Insights

by Sridhar R Gumpeny

  • Publisher : JP Medical Ltd
  • Release : 2016-02-12
  • Pages : 200
  • ISBN : 9351526453
  • Language : En, Es, Fr & De
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Advances in Diabetes: Novel Insights is an up-to-date collection of important advances in diabetology, covering the most recent developments in the field and providing insight into future progress in patient management. Illustrated with tables for quick reference, Advances in Diabetes: Novel Insights is an essential book for diabetologists and endocrinologists who wish to keep up to date with developments in their field.

Osteogenesis Imperfecta

Osteogenesis Imperfecta
A Translational Approach to Brittle Bone Disease

by Peter H. Byers,Paul Sponseller

  • Publisher : Academic Press
  • Release : 2013-08-06
  • Pages : 578
  • ISBN : 0123977894
  • Language : En, Es, Fr & De
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Osteogenesis Imperfecta is the first translational reference professionals can turn to for a source of comprehensive information on this disorder. Although several reviews of the field have been published in various journals, there is no other single source for a compendium of current information. Separate chapters discuss each of the several clinical features of OI. Ethical issues related to OI are discussed, as is the importance of nutrition in managing the OI child and the OI adult. The role of physical medicine and rehabilitation for OI patients is also presented, along with the current status of OI medical treatment and the prospects for genetic engineering in the future. The text also provides the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI. Incorporates chapters and information on the ethical issues related to osteogenesis imperfecta (OI) as will the importance of nutrition in managing the OI child and the OI adult Offers new insights into the underlying mechanisms of collagen biochemistry as related to OI as well as a presentation of intracellular collagen processing and the expanded role of protein chaperones in OI Discusses the role of physical medicine and rehabilitation for OI patients and the current status of OI medical treatment as well as prospects for genetic engineering in the future Provides a unique overview for the orthopedic surgeon with an advanced discussion of surgical techniques applicable to OI

Vitamin D, Chemical, Biochemical, and Clinical Endocrinology of Calcium Metabolism

Vitamin D, Chemical, Biochemical, and Clinical Endocrinology of Calcium Metabolism
Proceedings of the Fifth Workshop on Vitamin D, Williamsburg, VA, USA, February 1982

by Anthony W. Norman

  • Publisher : Unknown Publisher
  • Release : 1982
  • Pages : 1288
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Endocrinology

Endocrinology
A Book

by Leslie J. DeGroot

  • Publisher : W.B. Saunders Company
  • Release : 1989
  • Pages : 2776
  • ISBN : 9780721622217
  • Language : En, Es, Fr & De
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Revised throughout, the 5th Edition of this leading reference presents a complete and up-to-date review and analysis of all aspects of endocrinology, diabetes, and bone metabolism. Readers will also find state-of-the-art information on genetics, proteinomics, and hormone signaling, and coverage of the field's hottest topics in nearly 20 new chapters. Joined by an international team of leading expertsmany new to this editionDrs. Jameson and DeGroot provide guidance that integrates the basic science of endocrinology with clinical medicine and the practical management of endocrine disorders. A clinical focus emphasizes diagnosis and therapy.

Yen & Jaffe's Reproductive Endocrinology E-Book

Yen & Jaffe's Reproductive Endocrinology E-Book
Physiology, Pathophysiology, and Clinical Management

by Jerome F. Strauss,Robert L. Barbieri

  • Publisher : Elsevier Health Sciences
  • Release : 2013-08-28
  • Pages : 960
  • ISBN : 1455759724
  • Language : En, Es, Fr & De
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Yen & Jaffe’s Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for studying or as a quick reference when making daily diagnostic and therapeutic decisions, ensuring it's just the resource you need to offer your patients the best possible care. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout. Confidently perform procedures through expanded coverage of reproductive and infertility surgery. Apply the latest reproductive endocrinology advances in basic and clinical science, including molecular, cellular, and genetic concepts, and grasp their relevance to pathophysiology, diagnosis, and therapy. Maximize fertility in women and men undergoing chemotherapy and other cancer treatments, and counsel patients on environmental factors affecting reproduction. Stay on top of recent developments including the impact of obesity on fertility; ovarian tissue banking; cryopreservation; pre-implantation genetic diagnosis; ovulation induction; and risks and treatments for steroid hormone-responsive cancers. View basic anatomic structures, endocrine processes, and cell function and dysfunction with absolute clarity through full-color illustrations and new images throughout.

Pediatric Endocrinology

Pediatric Endocrinology
A Book

by M. Sperling

  • Publisher : W B Saunders Company
  • Release : 2002
  • Pages : 796
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This comprehensive, definitive reference in the field, incorporates all of today's explosive discoveries in basic and clinical endocrinology. Its reliable, cutting-edge guidance for a full range of problems is combined with a wealth of information on the physiological, biochemical, and genetic basis at the molecular biological level. Dr. Mark A. Sperling and 33 contributing experts bring readers the benefits of discovery at the bench and its application at the bedside. New chapters, extensive revisions, and compelling updates will keep readers at the forefront of the diagnosis and management of endocrine disease in children. Incorporates the explosive growth in molecular biology as it relates to developmental and pediatric endocrinology. Extensively revised and updated chapters throughout reflect the latest information. Coverage of up-to-the-minute topics in the field, including molecular, biochemical, and clinical basis of hyperinsulinemic hypoglycemia of infancy and childhood diabetes mellitus energy balance/obesity growth hormone paradigms of mechanisms of hormone action, and others Contributions from new authors from distinguished institutions Numerous brand-new illustrations depict the most current information, particularly the basic science/genetic basis of certain entities

Clinical Endocrinology of Calcium Metabolism

Clinical Endocrinology of Calcium Metabolism
A Book

by T. John Martin,Lawrence Gideon Raisz

  • Publisher : Marcel Dekker Incorporated
  • Release : 1987
  • Pages : 410
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Progress in Endocrinology

Progress in Endocrinology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1980
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Harrison's Endocrinology, 3E

Harrison's Endocrinology, 3E
A Book

by J. Larry Jameson

  • Publisher : McGraw Hill Professional
  • Release : 2013-03-22
  • Pages : 560
  • ISBN : 0071814876
  • Language : En, Es, Fr & De
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Endocrinology – as only HARRISON’S can cover it Featuring a superb compilation of chapters on endocrinology that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features An organization that reflects the physiologic roots of endocrinology: Pituitary, Thyroid, and Adrenal Disorders; Reproductive Endocrinology; Diabetes Mellitus, Obesity, Lipoprotein Metabolism; Disorders Affecting Multiple Endocrine Systems; and Disorders of Bone and Calcium Metabolism An important introduction that uses numerous examples of translational research to link genetics, cell biology, and physiology with pathophysiology and treatment Integration of pathophysiology with clinical management 108 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e Updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e 29 chapters written by physicians who are recognized experts in the field of endocrinology Helpful appendix of laboratory values of clinical importance

Maternal-Fetal and Neonatal Endocrinology

Maternal-Fetal and Neonatal Endocrinology
Physiology, Pathophysiology, and Clinical Management

by Christopher S. Kovacs,Cheri L. Deal

  • Publisher : Academic Press
  • Release : 2019-10-12
  • Pages : 1038
  • ISBN : 0128148241
  • Language : En, Es, Fr & De
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Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management systematically examines the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This reference volume expands coverage of specific disorders and diseases beyond the current endocrinology content on the market, which in most cases has a paragraph or no mention at all about pregnancy or aspects of fetal/neonatal development. Formalized source of maternal/fetal endocrine physiology and pathophysiology Key reference for fellows and residents for rarer endocrine pathologies Integrated presentation of new molecular and genetic causes of endocrine disorders Bridges the experience/knowledge gap of endocrinopathies rarely encountered in pregnancy

Stem Cells in Endocrinology

Stem Cells in Endocrinology
A Book

by Linda B. Lester

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-06
  • Pages : 274
  • ISBN : 1592599001
  • Language : En, Es, Fr & De
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A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

Endocrinology: Adult and Pediatric E-Book

Endocrinology: Adult and Pediatric E-Book
A Book

by J. Larry Jameson,Leslie J. De Groot

  • Publisher : Elsevier Health Sciences
  • Release : 2015-02-25
  • Pages : 2700
  • ISBN : 032332195X
  • Language : En, Es, Fr & De
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Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Consult this title on your favorite e-reader.

Endocrinology

Endocrinology
Proceedings of the Fourth International Congress of Endocrinology, Washington, D.C., June 18-24, 1972

by Robert O. Scow,Francis John Govier Ebling,I. W. Henderson

  • Publisher : Unknown Publisher
  • Release : 1973
  • Pages : 1280
  • ISBN : 9789021901664
  • Language : En, Es, Fr & De
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HIV and Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America,

HIV and Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America,
A Book

by Paul Hruz

  • Publisher : Elsevier Health Sciences
  • Release : 2014-08-17
  • Pages : 633
  • ISBN : 0323323227
  • Language : En, Es, Fr & De
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This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Paul Hruz, is devoted to HIV and Endocrine Disorders. Articles in this issue include: Dyslipidemia and cardiovascular risk in HIV infection; Changes in nutritional concerns in HIV/AIDS; HIV Lipodystrophy: Lessons learned about adipose tissue and metabolic disorders; Hypogonadism in the HIV infected male; Gonadal function and reproductive health in women with HIV; Osteopenia, osteoporosis, and fracture risk with HIV infection and treatment; HIV-associated calcium and vitamin D abnormalities; Alterations in pancreatic islet function in HIV; Insulin resistance, glucose intolerance, and diabetes in HIV; Thyroid abnormalities in HIV; HPA axis/adrenal pathology in HIV; and Endocrinopathies in HIV-infected children.

Endocrinology Index

Endocrinology Index
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1976
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Comparative Endocrinology of Calcium Regulation

The Comparative Endocrinology of Calcium Regulation
A Book

by Christopher G. Dacke

  • Publisher : Society for Endocrinology
  • Release : 1996
  • Pages : 220
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This text provides an overview of contemporary research in the area of comparative endocrinology of calcium and bone metabolism. It contains a collection of papers reviewing each main area of research: invertebrates, fish/amphibia, birds, and mammals. The papers were presented at a satellite workshop to the International Conference on Calcium Regulating Hormones held in Melbourne, Australia in February 1995. The book gives a comprehensive coverage of calcium regulation and includes topics as diverse as molluscan and dinosaur calcium metabolism. It includes the latest research on calcitonin gene-related and parathyroid hormone-related peptide function and the evolution of these hormones in lower vertebrates and invertebrates. The molecular biology of receptors to these peptides and to active metabolites of vitamin D also feature strongly.

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
A Book

by Murray J. Favus,Sylvia Christakos

  • Publisher : Unknown Publisher
  • Release : 1999
  • Pages : 502
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Anatomy and biology of bone matrix and cellular elements; Skeletal physiology; Mineral homeostasis; Clinical evaluation of bone and mineral disorders; Disorders of serum minerals; Metabolic bone diseases; Genetic, developmenal, and dysplastic skeletal disorders; Acquired disorders of cartilage and bone; Paget's disease; Extraskeletal (ectopic) calcification and ossification; Nephrolithiasis; Dentistry.