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Translational Research in Coronary Artery Disease

Translational Research in Coronary Artery Disease
Pathophysiology to Treatment

by Wilbert S. Aronow,John Arthur McClung

  • Publisher : Academic Press
  • Release : 2015-10-29
  • Pages : 244
  • ISBN : 0128026057
  • Language : En, Es, Fr & De
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Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Pathophysiology and Pharmacotherapy of Cardiovascular Disease

Pathophysiology and Pharmacotherapy of Cardiovascular Disease
A Book

by Gowraganahalli Jagadeesh,Pitchai Balakumar,Khin Maung-U

  • Publisher : Springer
  • Release : 2015-05-06
  • Pages : 1342
  • ISBN : 3319159615
  • Language : En, Es, Fr & De
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The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Myocardial Ischemia: New Insights for the Healthcare Professional: 2011 Edition

Myocardial Ischemia: New Insights for the Healthcare Professional: 2011 Edition
ScholarlyBrief

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 62
  • ISBN : 1464904561
  • Language : En, Es, Fr & De
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Myocardial Ischemia: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Myocardial Ischemia in a concise format. The editors have built Myocardial Ischemia: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Myocardial Ischemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Myocardial Ischemia: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Oxidative Stress in Heart Diseases

Oxidative Stress in Heart Diseases
A Book

by Sajal Chakraborti,Naranjan S Dhalla,Nirmal K Ganguly,Madhu Dikshit

  • Publisher : Springer Nature
  • Release : 2019-11-06
  • Pages : 596
  • ISBN : 9811382735
  • Language : En, Es, Fr & De
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This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Introduction to Translational Cardiovascular Research

Introduction to Translational Cardiovascular Research
A Book

by Dennis V. Cokkinos

  • Publisher : Springer
  • Release : 2014-11-06
  • Pages : 610
  • ISBN : 3319087983
  • Language : En, Es, Fr & De
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The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.

Myocardial Preservation

Myocardial Preservation
Translational Research and Clinical Application

by Dennis V. Cokkinos

  • Publisher : Springer
  • Release : 2019-01-28
  • Pages : 405
  • ISBN : 3319981862
  • Language : En, Es, Fr & De
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This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.

Braunwald's Heart Disease

Braunwald's Heart Disease
A Textbook of Cardiovascular Medicine. ...

by Douglas P. Zipes,Peter Libby,Robert O. Bonow,Douglas L. Mann,Gordon F. Tomaselli,Eugene Braunwald

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 1057
  • ISBN : 9789996118616
  • Language : En, Es, Fr & De
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Translational Vascular Medicine

Translational Vascular Medicine
Pathogenesis, Diagnosis, and Treatment

by David Abraham,Clive Handler,Michael Dashwood,Gerry Coghlan

  • Publisher : Springer Science & Business Media
  • Release : 2011-11-19
  • Pages : 266
  • ISBN : 9780857299208
  • Language : En, Es, Fr & De
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Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based. This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Coronary Calcium

Coronary Calcium
A Comprehensive Understanding of Its Biology, Use in Screening, and Interventional Management

by Aloke Virmani Finn

  • Publisher : Academic Press
  • Release : 2019-08-20
  • Pages : 270
  • ISBN : 0128165820
  • Language : En, Es, Fr & De
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Coronary Calcium: A Comprehensive Understanding of Its Biology, Use in Screening, and Interventional Management provides a comprehensive update on the current understanding of the significance of coronary artery calcification, showing the connection to the development of advanced atherosclerosis that will lead to better risk evaluations. Coverage includes information on the basic science behind the development of coronary calcium in atherosclerotic lesions, the pathology of calcified coronary lesions in humans, its differential development by race, and its relationship to plaque progression. Computed tomography is also covered to show the significance of coronary calcium for risk prediction and the potential role of various pharmacologic interventions. Each chapter contains summaries with salient and important points, making this book perfect for researchers and physicians interested in the field of vascular calcification. Provides an easy-to-read update on the current understanding of coronary calcium from a pathologic perspective Offers cutting-edge knowledge on the future of coronary calcium screening and authoritative opinions from experts Delivers relevant information for the evaluation of patients who may have coronary artery disease using coronary calcium as evaluated by CT in risk stratification and treatment

Braunwald's Heart Disease E-Book

Braunwald's Heart Disease E-Book
A Textbook of Cardiovascular Medicine

by Douglas P. Zipes,Peter Libby,Robert O. Bonow,Douglas L. Mann,Gordon F. Tomaselli

  • Publisher : Elsevier Health Sciences
  • Release : 2018-01-09
  • Pages : 2040
  • ISBN : 0323555934
  • Language : En, Es, Fr & De
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Trusted by generations of cardiologists for the latest, most reliable guidance in the field, Braunwald’s Heart Disease, 11th Edition, remains your #1 source of information on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. This award-winning text has been completely updated, providing a superior multimedia reference for every aspect of this fast-changing field, including new material about almost every topic in cardiology.

Braunwald's Heart Disease

Braunwald's Heart Disease
A Textbook of Cardiovascular Medicine

by Douglas P. Zipes

  • Publisher : Mosby
  • Release : 2018-02-19
  • Pages : 1944
  • ISBN : 9780323463423
  • Language : En, Es, Fr & De
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1 PL Global Burden of Cardiovascular Disease 2 DZ Ethical Decisions in Cardiovascular Medicine 3 DZ Clinical Decision Making in Cardiology 4 RB Measurement and Improvement of Quality of Care: Relevance to Cardiovascular Clinical Practice 5 DM Critical Evaluation of Clinical Trials 6 PL Personalized and Precision Cardiovascular Medicine 7 PL Principles of Cardiovascular Genetics 8 DZ Drug Therapeutics and Personalized Medicine 9 PL Biomarkers and Their Use in Precision Medicine 10 PL The History and Physical Examination: An Evidence-Based Approach 11 PL Evaluation and Management of the Noncardiac Surgical Patient- 12 DZ Electrocardiography 13 RB Exercise Testing 14 RB Echocardiography Appropriate Use Criteria: Echocardiography 15 RB The Chest Radiograph in Cardiovascular Disease 16 RB Nuclear Cardiology 17 Cardiovascular Magnetic Resonance 18 Cardiac Computed Tomography Appopriate Use Criteria: Multimodality Imaging in Stable Ischemic Heart Disease and Heart Failure 19 RB Cardiac Catheterization 20 Coronary Angiography and Intracoronary Imaging 21 DM Approach to the Patient With Heart Failure 22 DM Mechanisms of Cardiac Contraction and Relaxation 23 DM Pathophysiology of Heart Failure 24 DM Diagnosis and Management of Acute Heart Failure Guidelines: The Hospitalized Patient With Heart Failure 25 DM Management of Patients With Heart Failure With Reduced Ejection Fraction Guidelines: Management of Heart Failure with a Reduced Ejection Fraction 26 DM Heart Failure with a Preserved Ejection Fraction Guidelines: Heart Failure with a Preserved Ejection Fraction 27 DM Devices for Monitoring and Managing Heart Failure Guidelines: Cardiac Resynchronization Therapy and Implantable Cardioverter- Defibrillators for Heart Failure with a Reduced Ejection Fraction 28 DM Surgical Management of Heart Failure 29 DM Mechanical Circulatory Support 30 DM Cardiovascular Regeneration and Repair 31 DM Management of Patients with Advanced Heart Failure 32 DZ Approach to the Patient with Cardiac Arrhythmias 33 DZ Genetics of Cardiac Arrhythmias 34 DZ Mechanisms of Cardiac Arrhythmias 35 DZ Diagnosis of Cardiac Arrhythmias Guidelines: Ambulatory Electrocardiographic and Electrophysiological Testing 36 DZ General Therapy for Cardiac Arrhythmias 37 DZ Supraventricular Arrhythmias 38 DZ Atrial Fibrillation: Clinical Features, Mechanisms, and Management Guidelines: Atrial Fibrillation 39 DZ Ventricular Arrhythmias 40 DZ Bradycardia Arrhythmias 41 DZ Pacemakers and Implantable Cardioverter-Defibrillators Guidelines: Cardiac Pacemakers and Cardioverter-Defibrillators 42 DZ Cardiac Arrest and Sudden Cardiac Death 43 DZ Hypotension and Syncope Guidelines 44 PL The Vascular Biology of Atherosclerosis 45 PL Risk Markers and the Primary Prevention of Cardiovascular Disease 46 PL Systemic Hypertension: Mechanisms and Diagnosis 47 PL Systemic Hypertension: Management Guidelines: Treatment of Hypertension 48 PL Lipid Disorders and Cardiovascular Disease Guidelines: Management of Lipids 49 PL Nutrition and Cardiometabolic Diseases 50 Obesity and Cardiometabolic Disease 51 Diabetes and the Cardiovascular System Guidelines: Diabetes and Heart Disease 52 RB Environmental Exposures and CVD 53 PL Exercise and Sports Cardiology 54 PL Comprehensive Cardiac Rehabilitation 55 DZ Complementary Approaches to Heart Disease Management 56 PL Approach to the Patient with Chest Pain 57 RB Coronary Blood Flow and Myocardial Ischemia 58 PL ST-Elevation Myocardial Infarction: Pathology, Pathophysiology, and Clinical Features 59 PL ST-Elevation Myocardial Infarction: Management Guidelines: Management of Patients with ST-Elevation Myocardial Infarction 60 PL Non-ST Elevation Acute Coronary Syndromes Guidelines: Unstable Angina and Non-ST Elevation Myocardial Infarction

Coronary Heart Disease: New Insights for the Healthcare Professional: 2013 Edition

Coronary Heart Disease: New Insights for the Healthcare Professional: 2013 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2013-07-22
  • Pages : 504
  • ISBN : 1481651773
  • Language : En, Es, Fr & De
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Coronary Heart Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Coronary Heart Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Coronary Heart Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair
From Basic Research to Clinical Applications

by Nabil Dib,Doris A. Taylor,Edward B. Diethrich

  • Publisher : Springer Science & Business Media
  • Release : 2006-04-09
  • Pages : 335
  • ISBN : 038730939X
  • Language : En, Es, Fr & De
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In excess of 7 million people worldwide die of coronary heart disease each year. Only one-third of these heart attack victims recover completely. The remainder suffer the consequences of myocardial infarction and its ill fated remodeling process, resulting in chronic congestive heart failure. This malady alone is the leading cause of hospital admissions in the United States. New breakthroughs in stem cell therapy and tissue engineering have promised to reverse this dismal outcome by cardiovascular repair. World authorities, including scientists and regulatory authorities, have joined in a collaborative effort to present for the reader the first collective review of stem cell therapy for the treatment of cardiovascular disease. These contributions in basic science, pre-clinical and clinical experience guided by the regulatory pathways, assure a rapid course of translational research and clinical trials. The contents of this publication will become a prerequisite for those preparing to meet the challenges of this exciting and potentially rewarding field of stem cell research.

Topics in Arrhythmias and Ischemic Heart Disease

Topics in Arrhythmias and Ischemic Heart Disease
A Book

by Dr. Craig T. Basson, MD, PhD,Dr. Bruce B. Lerman, MD

  • Publisher : Demos Medical Publishing
  • Release : 2009-12-15
  • Pages : 400
  • ISBN : 9781935281740
  • Language : En, Es, Fr & De
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In order to provide the latest and most sophisticated treatment the cardiology clinician must have current knowledge of a vast amount of translational research in the pathophysiology of these disorders as well as be aware of recent advances and issues in pharmacogenic and interventional therapies. Topics in Arrhythmias and Ischemic Heart Disease provides expert reviews and assessment of the most recent clinical research and on current trends in evaluation, diagnosis, and clinical management. Reviews include assessment of emerging data and indications of likely key advances with signifiacnt impact on clinical research in the near future. This volume is a must-have for every cardiologist needing to be fully current on recent advances in ischemic heart disease and arrhythmic disorders. About the Series Developed by expert faculty at the Cornell Division of Cardiology, the Emerging Concepts in Cardiology series edited by Craig T. Basson and Bruce B. Lerman, provides "state of the art reviews" of each topic from a clinical perspective, with expert perspectives in current clinical research and emerging basic and traditional research issues all in a concise, attractive and well-illustrated texts.

Topics in Arrhythmias and Ischemic Heart Disease

Topics in Arrhythmias and Ischemic Heart Disease
A Book

by Dr. Bruce B. Lerman, MD,Dr. Craig T. Basson, MD, PhD

  • Publisher : Demos Medical
  • Release : 2009-12-15
  • Pages : 186
  • ISBN : 9781933864587
  • Language : En, Es, Fr & De
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"In order to provide the latest and most sophisticated treatment the cardiology clinician must have current knowledge of a vast amount of translational research in the pathophysiology of these disorders as well as be aware of recent advances and issues in pharmacogenic and interventional therapies. Topics in Arrhythmias and Ischemic Heart Disease provides expert reviews and assessment of the most recent clinical research and on current trends in evaluation, diagnosis, and clinical management. Reviews include assessment of emerging data and indications of likely key advances with signifiacnt impact on clinical research in the near future. This volume is a must-have for every cardiologist needing to be fully current on recent advances in ischemic heart disease and arrhythmic disorders. About the Series Developed by expert faculty at the Cornell Division of Cardiology, the Emerging Concepts in Cardiology series edited by Craig T. Basson and Bruce B. Lerman, provides "state of the art reviews" of each topic from a clinical perspective, with expert perspectives in current clinical research and emerging basic and traditional research issues all in a concise, attractive and well-illustrated texts. "

Heart Catheterization: New Insights for the Healthcare Professional: 2012 Edition

Heart Catheterization: New Insights for the Healthcare Professional: 2012 Edition
ScholarlyPaper

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-12-10
  • Pages : 22
  • ISBN : 146498400X
  • Language : En, Es, Fr & De
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Heart Catheterization: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Heart Catheterization in a compact format. The editors have built Heart Catheterization: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heart Catheterization in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Heart Catheterization: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Topics in Structural Heart Disease

Topics in Structural Heart Disease
A Book

by Dr. Craig T. Basson, MD, PhD,Dr. Bruce B. Lerman, MD

  • Publisher : Demos Medical Publishing
  • Release : 2009-12-11
  • Pages : 192
  • ISBN : 9781935281757
  • Language : En, Es, Fr & De
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In order to provide the latest and most sophisticated treatment, cardiology physicians must possess current knowledge of a vast amount of translational research in the pathophysiology of structural heart disease and its associated disorders as well as recent advances in diagnostic techniques and pharacogenic and interventional therapies. Topics in Structural Heart Disease provides expert reviews and assessment of the most recent clinical research and on current trends in evaluation, diagnosis, and clinical management. Reviews include assessment of emerging data and indications of likely key advances with significant impact on clinical practice in the near future. This volume is a must-have for every cardiologist needing to be fully current on recent advances in structural heart disease and its associated disorders. About the Series Developed by expert faculty at the Cornell Division of Cardiology, the Emerging Concepts in Cardiology series edited by Craig T. Basson and Bruce B. Lerman, provides "state of the art" reviews of each topic from a clinical perspective, with expert analysis of current clinical research and emerging basic and traditional research issues all in concise, attractive and well-illustrated texts.

Cardiac Extracellular Matrix

Cardiac Extracellular Matrix
Fundamental Science to Clinical Applications

by Eric G. Schmuck,Peiman Hematti,Amish N. Raval

  • Publisher : Springer
  • Release : 2018-09-20
  • Pages : 246
  • ISBN : 3319974211
  • Language : En, Es, Fr & De
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This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

Coronary Heart Disease: New Insights for the Healthcare Professional: 2011 Edition

Coronary Heart Disease: New Insights for the Healthcare Professional: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 305
  • ISBN : 146490054X
  • Language : En, Es, Fr & De
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Coronary Heart Disease: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Coronary Heart Disease. The editors have built Coronary Heart Disease: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Coronary Heart Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Coronary Heart Disease: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Clinical Handbook of Coronary Artery Disease

Clinical Handbook of Coronary Artery Disease
A Book

by Gundu HR Rao

  • Publisher : Jaypee Brothers Medical Publishers
  • Release : 2020-08-31
  • Pages : 520
  • ISBN : 938918830X
  • Language : En, Es, Fr & De
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