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Human Vaccines

Human Vaccines
Emerging Technologies in Design and Development

by Kayvon Modjarrad,Wayne C. Koff

  • Publisher : Academic Press
  • Release : 2016-10-15
  • Pages : 186
  • ISBN : 0128025425
  • Language : En, Es, Fr & De
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Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology. Introduces new topics in vaccine immunology in the context vaccine design and production Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 – 3 decades Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety Provides a broad overview of innovative vaccine technologies, including immunological aspects

Vaccines

Vaccines
A Book

by Stanley A. Plotkin,Walter Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2008-02-11
  • Pages : 1748
  • ISBN : 1437721583
  • Language : En, Es, Fr & De
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Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.

Vaccines For Dummies

Vaccines For Dummies
A Book

by Megan Coffee,Sharon Perkins

  • Publisher : John Wiley & Sons
  • Release : 2021-08-03
  • Pages : 256
  • ISBN : 1119787815
  • Language : En, Es, Fr & De
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Inoculate yourself against the confusion and misinformation surrounding vaccines Measles, mumps, and rubella—oh my! Why are we vaccinating our children—and ourselves—against these diseases, and what goes on in our bodies after the needle comes out? Vaccines For Dummies will inform and entertain you about all things vax, including how the first vaccines were discovered, what’s in modern vaccines, how they are tested and approved for use, and why the CDC’s vaccine schedule is what it is. Inside, you’ll also find a complete guide to vaccine benefits, potential side effects, and contraindications, so you’ll be ready when shot time comes. From the very first inoculations hundreds of years ago to the brand new COVID-19 shot, creating immunity to diseases has become a human specialty. If you’re wondering how safe and how necessary it all is, you aren’t alone. In Vaccines For Dummies, we’ll explore the issue from every angle, empowering you to take charge of your wellbeing. With this book, you will: Discover the ABCs of vaccines, including what they’re made of and how they work Learn about each recommended childhood and adult immunization, plus the seasonal flu shot, all with this evidence-based guide Take a journey through vaccine history, meeting the major players of yesterday and today Decide what’s right for your family, with the help of the most recent vaccine science Parents, parents-to-be, adults of any age, and anyone who wants to delve into the microscopic world of pathogens and their arch nemeses (antigens and antibodies) will get a double dose of knowledge from Vaccines For Dummies.

Vaccines for Biodefense and Emerging and Neglected Diseases

Vaccines for Biodefense and Emerging and Neglected Diseases
A Book

by Alan D.T. Barrett,Lawrence R. Stanberry

  • Publisher : Academic Press
  • Release : 2009-03-05
  • Pages : 1488
  • ISBN : 9780080919027
  • Language : En, Es, Fr & De
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The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. * Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats * Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace * Each chapter will include a map of the world showing where that particular disease is naturally found

Veterinary Vaccines

Veterinary Vaccines
A Book

by R. Pandey,S. Höglund,G. Prasad

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 342
  • ISBN : 1461392268
  • Language : En, Es, Fr & De
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Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine that enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out. A new breed of vaccines is on the horizon that seeks to control fertility. Originally conceived to intercept a step in the reproductive process, they are conceptual models for developing approaches to regulate the body's internal processes.

Vaccines E-Book

Vaccines E-Book
A Book

by Stanley A. Plotkin,Walter Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2012-09-22
  • Pages : 1570
  • ISBN : 1455737984
  • Language : En, Es, Fr & De
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Apply the latest vaccination knowledge with a reference that Bill Gates calls "an indispensable guide to the enhancement of the well-being of our world." Inside Vaccines, you’ll find comprehensive and current coverage of every aspect of vaccination, from the development of each vaccine to its use in reducing disease. This medical reference book offers the expert information you need to apply the very latest techniques and information in your practice! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Gain a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Update your knowledge of both existing vaccines and vaccines currently in the research and development stage. Get complete answers on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyze the cost-benefit and cost-effectiveness of different vaccine options. Clearly visualize concepts and objective data through an abundance of tables and figures. Make optimal use of the latest vaccines for pneumococcal disease, rotavirus, human papillomavirus, herpes zoster, meningococcal disease, and much more. Stay at the forefront of new developments with completely updated chapters on malaria and HIV vaccines, a new chapter on vaccine regulations across the world, and many other revisions throughout.

Pediatric Vaccines and Vaccinations

Pediatric Vaccines and Vaccinations
A European Textbook

by Timo Vesikari,Pierre Van Damme

  • Publisher : Springer
  • Release : 2017-11-01
  • Pages : 264
  • ISBN : 3319599526
  • Language : En, Es, Fr & De
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This graduate textbook serves as a highly readable guide on vaccines and vaccination in infants, children and adolescents from an European perspective. The first part of the book is dedicated to childhood and adolescent vaccine schedules, maternal and neonatal immunization and safety of vaccines. In a second part we focus on viral and bacterial vaccines. Further chapters discuss pediatric travel vaccines, vaccines in the pipeline and the European registration process. This book is intended to be a reference textbook and will help to standardize the information on vaccines and immunization program in the WHO European Region.

Travelers' Vaccines

Travelers' Vaccines
A Book

by Jane N. Zuckerman,Elaine C. Jong

  • Publisher : PMPH-USA
  • Release : 2010
  • Pages : 573
  • ISBN : 1607950456
  • Language : En, Es, Fr & De
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Rev. ed. of: Travelers' vaccines / Elaine C. Jong, Jane N. Zuckerman. 2004.

Vaccines

Vaccines
A Book

by Peter Perlman,Hans Wigzell

  • Publisher : Springer
  • Release : 2011-12-21
  • Pages : 534
  • ISBN : 9783642641961
  • Language : En, Es, Fr & De
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The immune system is the only organ system in the body besides the central nervous systems endowed with memory. Both types of memories are specific and long-lasting, sometimes life long. This memory capacity of the immune system provides the basis for the most cost-efficient of all medical interventions, successful vaccinations against many common infectious diseases. Such a success requires the isolation of the infectious agent or toxic substance, methods to grow and/or purify the relevant antigen and change it into something innocuous whilst maintaining its immunogenicity. Whereas the early vaccines could only use the enhanced resistance against infectious disease as a measure of vaccine efficacy, most modern vaccines rely upon standardized laboratory tests accepted to parallel the in vivo protective capacity to confirm the quality and potency of the respective vaccine. We are presently experiencing an explosion in the development of new and/or improved vaccines. This is largely due to a parallel rapid expansion in our knowledge of the immune system and of the detailed molecular structure and function of microorganisms. Using this knowledge it is now possible to compose vaccines of new types where only certain molecules (or parts of molecules) derived from a pathogen are included, excluding other potentially harmful ones. Whereas earlier attenuated live vaccines were created by em pirical means such vaccines can now be created by molecularly defined inter ventions in the genome of the microorganism.

Vaccines

Vaccines
What Everyone Needs to Know®

by Kristen A. Feemster

  • Publisher : Oxford University Press
  • Release : 2017
  • Pages : 256
  • ISBN : 0190277912
  • Language : En, Es, Fr & De
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"Vaccines are one of the most important public health achievements of our time. But now as many vaccine preventable diseases are no longer perceived an imminent threat, vaccines are both lauded and feared, amplified by rapid-fire dissemination of conflicting messages. This book will follow the story of vaccines in the past, present and future to disentangle fact from fiction and underscore their important role in our society"--

Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness

Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness
A Book

by Thomas Cowan

  • Publisher : Chelsea Green Publishing
  • Release : 2018-05-24
  • Pages : 192
  • ISBN : 1603587772
  • Language : En, Es, Fr & De
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Over the past 50 years, rates of chronic illness, learning disabilities, and allergies in children have exploded--1 in 6 children has a diagnosed learning disorder, 1 in 50 has autism, and 1 in 13 has severe food allergies. Instead of blaming genetics or increased awareness and diagnosis, author Thomas Cowan, MD, attributes these rising numbers to our current vaccination policy. In Vaccines, Auto-Immunity, and the Assault on Childhood, Cowan combines his years of experience as a medical practitioner with his research into the history and science of vaccines to show how childhood illnesses, which help children to develop a robust immune system, are now eschewed by conventional medicine in favor of an increasing array of vaccinations that do more harm than good. Invoking philosopher Rudolph Steiner's vision of vaccines as inspired by "spirits of darkness," Cowan brings to light the various ways in which scientists and government officials work to promote a vaccine program that only increases suffering. Along the way he questions commonly held views of cell biology, the role of water in the body, and the spatial and spiritual components of autism. Additionally, he provides hope of recovery in the form of a nontoxic course of treatment for those suffering chronic inflammation and other averse immune responses to vaccines. Cowan's thoughtfully bold writing takes us on a journey into the history of illness, questioning the true origins of diseases such as polio, and asking important questions, such as: why did paralytic polio make a sudden appearance in the US in the years between 1916-1918? The answers lie far beyond what conventional medicine would have us believe. Vaccines, Auto-Immunity, and the Assault on Childhood asks that we re-examine not only our modern health system but our relationship with the spiritual world. Only then will we find true health.

Vaccines: History, Science, and Issues

Vaccines: History, Science, and Issues
A Book

by Tish Davidson

  • Publisher : ABC-CLIO
  • Release : 2017-06-15
  • Pages : 259
  • ISBN : 1440844445
  • Language : En, Es, Fr & De
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Providing scientifically accurate, detailed, and accessible information to students and general readers, this book presents the history of vaccination; describes the administration, manufacturing, and regulation of vaccines in the United States; and explains the most recent scientific findings about vaccination while addressing concerns of those who oppose immunization. • Explains in depth the uses, dosage, adverse events, contraindications, and limitations of every vaccine • Provides a detailed, scientific explanation of the mechanism by which vaccines create immunity • Examines current controversies in vaccine usage and their scientific and social basis • Offers an international perspective on vaccine development and use • Documents the anti-vaccination movement that has existed from the 18th century through today

Vaccines and Autoimmunity

Vaccines and Autoimmunity
A Book

by Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic

  • Publisher : John Wiley & Sons
  • Release : 2015-07-07
  • Pages : 384
  • ISBN : 1118663438
  • Language : En, Es, Fr & De
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In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

The Vaccine Book

The Vaccine Book
A Book

by Barry R. Bloom,Paul Henri Lambert

  • Publisher : Academic Press
  • Release : 2003
  • Pages : 436
  • ISBN : 0121072584
  • Language : En, Es, Fr & De
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The Vaccine Book provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. The Vaccine Book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. Topics unique to this book: * Ethics * Economics * Diseases that could be prevented * Clinical trial designs * Ideas about the future of vaccines * Challenges facing research scientists in the vaccine area * Burden of vaccine-preventable illness and the impact of vaccines * Scientific obstacles to be overcome by existing and new vaccines * Basic mechanisms of host immunity and pathogen interaction with host tissues * New approaches to future vaccines against challenging diseases * Real and perceived safety issues which dominate vaccine development and vaccination policies * Microbial pathogenesis as a basis for vaccine design * Planning vaccine trials * Introducing new vaccines into the healthcare system * Future challenges for vaccines and immunizations

Vaccines

Vaccines
A Book

by Stanley A. Plotkin,Walter A. Orenstein,Paul A. Offit

  • Publisher : Elsevier Health Sciences
  • Release : 2008
  • Pages : 1725
  • ISBN : 1416036113
  • Language : En, Es, Fr & De
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Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination--from development to use in reducing disease. It also includes access to a companion Web site for more coverage.

Fish Vaccines

Fish Vaccines
A Book

by Alexandra Adams

  • Publisher : Springer
  • Release : 2016-10-31
  • Pages : 180
  • ISBN : 9783034809788
  • Language : En, Es, Fr & De
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This book provides a useful text for research students and scientists on the latest knowledge about the immune system of fish, cutting edge technologies and the step required to develop, test and commercialise fish vaccines. It brings together information that is currently difficult to obtain in one book, and highlights problem areas and research topics that still need to be addressed to improve future vaccines.

Vaccines

Vaccines
A Book

by Carol Hand

  • Publisher : ABDO Publishing Company
  • Release : 2013-09-01
  • Pages : 112
  • ISBN : 1624013767
  • Language : En, Es, Fr & De
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Amazing medical breakthroughs are made every day. In the past decades, medical researchers have cured diseases that were once deadly and devised new methods to heal that were once unimaginable. This title follows the development of vaccines, including the race to stop polio, groundbreaking discoveries and the doctors who made them, and where the science is heading in the future. Learn how immunization and vaccines work and how scientists are making them safer. Sidebars, full-color photos, a glossary, and well-placed graphs, charts, and maps, enhance this engaging title. Aligned to Common Core Standards and correlated to state standards. Essential Library is an imprint of ABDO Publishing Company.

Vaccines E-Book

Vaccines E-Book
A Book

by Stanley A. Plotkin,Walter Orenstein,Paul A. Offit,Kathryn M. Edwards

  • Publisher : Elsevier Health Sciences
  • Release : 2017-04-07
  • Pages : 1376
  • ISBN : 0323393012
  • Language : En, Es, Fr & De
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From the development of each vaccine to its use in reducing disease, Plotkin’s Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin’s Vaccines is a must-have reference for current, authoritative information in this fast-moving field. Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyzes the cost-benefit and cost-effectiveness of different vaccine options. Helps you clearly visualize concepts and objective data through an abundance of tables and figures. Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. Features a new chapter on maternal immunization.

No Vaccines for Me!

No Vaccines for Me!
A Book

by Kathleen Dunkelberger Rn Bc Clnc

  • Publisher : AuthorHouse
  • Release : 2010-10
  • Pages : 44
  • ISBN : 145209179X
  • Language : En, Es, Fr & De
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Although I am considered an advocate for people with autism and their families, this is not an autism book. Autism probably has different causes, and I don't believe all people with autism are vaccine-injured. I do believe that vaccines cause autism and perhaps affect the level of severity of the medical and neurological symptoms one with autism might experience. This prompted me to do my own research into what I found to be the horrors of vaccines, which far surpass one medical diagnosis or condition. I decided to write No Vaccines for Me! because, although many books and Web sites about vaccine dangers and side effects are available for parents, I could not find any resources for a younger audience. There were no family books available for parents to use to educate their children. Thus, I wrote No Vaccines for Me! as a family book and not as a children's book. It is intended as a resource for like-minded parents who choose not to vaccinate and who wish to make informed decisions about vaccinations, nutrition, and overall health. It is not intended to be controversial, although it may be viewed as such. This book is an interactive reading tool intended to facilitate dialogue between parents and children and to inspire them to develop a health and wellness plan. It is written to educate families about informed consent, to explain their right to refuse vaccines, and to assist them with becoming more confident in discussing and making their own health care decisions. My hope and expectation are that parents will read this book to their children and explain the content in more detail.

Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity
A Book

by Rimas Orentas,James W. Hodge,Bryon D. Johnson

  • Publisher : John Wiley & Sons
  • Release : 2007-10-26
  • Pages : 352
  • ISBN : 9780470170106
  • Language : En, Es, Fr & De
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Cancer Vaccines and Tumor Immunity offers a review of the basic scientific discoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation, T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.